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公开(公告)号:US20170355991A1
公开(公告)日:2017-12-14
申请号:US15691243
申请日:2017-08-30
发明人: XU HU , JAMES PRESNAIL , NINA RICHTMAN , SCOTT DIEHN , MICHELLE VAN ALLEN , LISA PROCYK
IPC分类号: C12N15/113 , C12N15/82 , A01N37/46 , A01N63/02
CPC分类号: C12N15/113 , A01N37/46 , A01N63/02 , C12N15/8218 , C12N15/8286 , C12N2310/14 , C12N2310/531 , Y02A40/162
摘要: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: disclosed herein, (but not including the forward and reverse primers.) or active variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiments, the pest is D. virgifera virgifera, D. barberi, D. virgifera zeae, D. speciosa, D. speciosa, or D. undecimpunctata howardi. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
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公开(公告)号:US20200172918A1
公开(公告)日:2020-06-04
申请号:US16790095
申请日:2020-02-13
发明人: XU HU , JAMES KEVIN PRESNAIL , NINA RICHTMAN , LISA PROCYK
摘要: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
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公开(公告)号:US20200231985A1
公开(公告)日:2020-07-23
申请号:US16839691
申请日:2020-04-03
发明人: XU HU , BLISS MARIE KERNODLE , MOLLIE MARY MCMAHON , ADANE KASSA , XIPING NIU , JAMES KEVIN PRESNAIL , ALBERT L LU , NINA RICHTMAN , JONATHAN WILLIAM ROBESON
IPC分类号: C12N15/82 , A01N63/30 , A01N63/10 , A01N65/00 , A01N37/46 , C07K14/435 , C12N15/113
摘要: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号:US20180155739A1
公开(公告)日:2018-06-07
申请号:US15736369
申请日:2016-06-16
发明人: XU HU , BLISS MARIE KERNODLE , MOLLY MARY MCMAHON , ADANE KASSA , XIPING NIU , JAMES KEVIN PRESNAIL , ALBERT L. LU , NINA RICHTMAN , JONATHAN WILLIAM ROBESON
IPC分类号: C12N15/82 , C12N15/113
CPC分类号: C12N15/8286 , A01N37/46 , A01N63/02 , A01N63/04 , A01N65/00 , C07K14/43536 , C07K14/43563 , C12N15/113 , C12N15/8218 , C12N2310/14 , C12N2310/531 , Y02A40/162
摘要: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号:US20240002842A1
公开(公告)日:2024-01-04
申请号:US17821204
申请日:2022-08-22
发明人: XU HU , JAMES KEVIN PRESNAIL , NINA RICHTMAN , SCOTT DIEHN , MICHELLE VAN ALLEN , LISA PROCYK
IPC分类号: C12N15/113 , A01N37/46 , C12N15/82 , A01N63/60
CPC分类号: C12N15/113 , A01N37/46 , C12N15/8218 , C12N15/8286 , A01N63/60 , C12N2310/14 , C12N2310/531 , Y02A40/146
摘要: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides various target polynucleotides set forth in any one of SEQ ID NOS: disclosed herein, (but not including the forward and reverse primers.) or active variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiments, the pest is D. virgifera virgifera, D. barberi, D. virgifera zeae, D. speciosa, D. speciosa, or D. undecimpunctata howardi. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
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公开(公告)号:US20220267792A1
公开(公告)日:2022-08-25
申请号:US17661297
申请日:2022-04-29
发明人: XU HU , BLISS MARIE KERNODLE , MOLLIE MARY MCMAHON , ADANE KASSA , XIPING NIU , JAMES KEVIN PRESNAIL , ALBERT L. LU , NINA RICHTMAN , JONATHAN WILLIAM ROBESON
IPC分类号: C12N15/82 , C07K14/435 , A01N37/46 , A01N65/00 , A01N63/60 , C12N15/113
摘要: Methods and compositions are provided which employ a silencing element that, when ingested by a plant insect pest, such as Coleopteran, Hemiptera, or Lepidopteran plant pest, including a Diabrotica, Leptinotarsa, Phyllotreta, Acyrthosiphan, Bemisia, Halyomorpha, Nezara, or Spodoptera plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: 1-53 or 107-254 disclosed herein, or variants and fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest and pest population by insect sterilization (i.e., male and female sterility, reduction of sperm count, egg production and viability) and mating-based sterile insect technique (SIT). Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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公开(公告)号:US20170253887A1
公开(公告)日:2017-09-07
申请号:US15511196
申请日:2015-08-31
发明人: XU HU , XIPING NIU , MEGHAN ONEAL , JAMES K. PRESNAIL , NINA RICHTMAN , JOE ZHAO
IPC分类号: C12N15/82 , C12N15/113
CPC分类号: C12N15/8286 , C12N15/113 , C12N15/8218 , C12N2310/14 , C12N2310/531 , Y02A40/162
摘要: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. Disclosed are various target polynucleotides set forth in any one of SEQ ID NOS: disclosed herein, (but not including the forward and reverse primers.) or variants or fragments thereof, or complements thereof, wherein a decrease in expression of one or more of the sequences in the target pest controls the pest (i.e., has insecticidal activity). Plants, plant parts, bacteria and other host cells comprising the silencing elements, variants or fragments thereof, or complements thereof, are also provided.
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公开(公告)号:US20240084319A1
公开(公告)日:2024-03-14
申请号:US18307973
申请日:2023-04-27
发明人: XU HU , JAMES KEVIN PRESNAIL , NINA RICHTMAN , LISA PROCYK
CPC分类号: C12N15/8218 , A01N57/20 , C12N15/8286 , Y02A40/146
摘要: Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a Coleopteran plant pest or a Diabrotica plant pest, decrease the expression of a target sequence in the pest. Plants, plant parts, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
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公开(公告)号:US20190185867A1
公开(公告)日:2019-06-20
申请号:US16309171
申请日:2017-06-02
发明人: XU HU , XIPING NIU , NINA RICHTMAN
IPC分类号: C12N15/82
CPC分类号: C12N15/8218 , C07K14/43563 , C12N15/8286 , Y02A40/162
摘要: The present invention relates generally to methods of molecular biology and gene silencing to control pests.
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