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公开(公告)号：US12084670B2
公开(公告)日：2024-09-10
申请号：US18093784
申请日：2023-01-05
发明人： Takashi Hashimoto , Akira Kato
CPC分类号： C12N15/8218 , A24B13/00 , A24B15/10 , A61K31/455 , C12N9/0004 , C12N9/0012 , C12N9/0022 , C12N15/8216 , C12N15/8243 , C12N15/8279 , C12N15/8286 , C12Y104/03006 , Y02A40/146
摘要： MPO1 and MPO2 can be regulated for either decreasing or increasing alkaloid levels in plants, in particular in Nicotiana plants. In particular, suppressing or overexpressing one or more of MPO1 and MPO2 may be used to decrease or increase nicotine and nicotinic alkaloid levels in tobacco plants. Suppression or overexpression of one or more of MPO1 and MPO2 may be used in combination with modification of expression of other genes encoding enzymes on the nicotinic alkaloid biosynthetic pathway such as A622, NBB1, PMT, and QPT.
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公开(公告)号：US12065656B2
公开(公告)日：2024-08-20
申请号：US17237489
申请日：2021-04-22
发明人： Jennifer Kara Barry , Kevin Hayes , Lu Liu , Eric Schepers , Nasser Yalpani
CPC分类号： C12N15/8286 , A01N47/44 , A01N63/10 , A01N63/50 , A01N65/00 , C07K14/415 , A01N65/04 , C07K2319/00 , Y02A40/146
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
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公开(公告)号：US20240262872A1
公开(公告)日：2024-08-08
申请号：US18595330
申请日：2024-03-04
发明人： James A. Baum , Artem G. Evdokimov , Stanislaw Flasinski , Farhad Moshiri , Timothy J. Rydel , Eric J. Sturman , Moritz von Rechenberg , Halong Vu , Andrew M. Wollacott , Meiying Zheng
IPC分类号： C07K14/325 , A01N37/46 , C07K14/00 , C07K14/32 , C07K14/435 , C12N15/82
CPC分类号： C07K14/325 , A01N37/46 , C07K14/001 , C07K14/32 , C07K14/43577 , C12N15/8286 , Y02A40/146
摘要： The present invention discloses Hemipteran insect inhibitory proteins, methods of using such proteins, nucleotide sequences encoding such proteins, methods of detecting and isolating such proteins, and their use in agricultural systems.
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4.发明公开公开(公告)号：US20240167049A1
公开(公告)日：2024-05-23
申请号：US18499906
申请日：2023-11-01
申请人： CERES, INC.
IPC分类号： C12N15/82 , C07K14/415
CPC分类号： C12N15/8273 , C07K14/415 , C12N15/8242 , C12N15/8261 , C12N15/8271 , Y02A40/146
摘要： Isolated polynucleotides and polypeptides encoded thereby are described, together with the use of those products for making transgenic plants with increased tolerance to abiotic stress (e.g., high or low temperature, drought, flood).
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公开(公告)号：US11990205B2
公开(公告)日：2024-05-21
申请号：US15940695
申请日：2018-03-29
IPC分类号： G16B20/00 , A01H1/04 , C12N15/82 , C12Q1/6895 , G16B20/50 , G16B40/00 , G16B20/20 , G16B25/00
CPC分类号： G16B20/00 , A01H1/04 , C12N15/8261 , C12Q1/6895 , G16B20/50 , G16B40/00 , C12N15/8243 , Y02A40/146
摘要： Exemplary systems and methods for selecting from population of candidate edits and predicting an aggregate effect of the candidate edits are disclosed. One exemplary method includes identifying a population of candidate edits to a genomic sequence of said organism and ranking each of the candidate edits based on a predicted ability of each candidate edit to affect a trait of interest in said organism. The exemplary method further includes selecting one or more of the candidate edits based on the ranking and predicting, by the computing device, an aggregate effect of the selected one or more of the candidate edits for the trait of interest when expressed by a specimen of the organism having a genomic sequence and edited according to the selected one or more of the candidate edits, as compared to an unedited specimen of the organism.
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公开(公告)号：US20240117374A1
公开(公告)日：2024-04-11
申请号：US18497825
申请日：2023-10-30
发明人： Timothy K. Ball , Artem G. Evdokimov , Larry A. Gilbertson , Victor M. Guzov , Jeffrey A. Haas , Qing Huai , Sergey Ivashuta , Melissa M. Kemp , Yifei Kong , Thomas M. Malvar , Byron V. Olsen , Parthasarathy Ramaseshadri , Brian E. Weiner
IPC分类号： C12N15/82 , A01N37/44 , A01N37/46 , C07K14/325
CPC分类号： C12N15/8286 , A01N37/44 , A01N37/46 , C07K14/325 , Y02A40/146
摘要： Pesticidal proteins are provided that combine two or more modes of action into a single molecule. These pesticidal proteins therefor exhibit greater efficacy and/or durability of resistance, for the purposes of pest control, and can be utilized for pest control by provision in the diet of a pest organism, or by topical application to crop plants and/or pests. Methods and compositions for producing and using such proteins are also provided.
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公开(公告)号：US11939589B2
公开(公告)日：2024-03-26
申请号：US17729892
申请日：2022-04-26
发明人： James A. Baum , Claire A. CaJacob , Pascale Feldmann , Gregory R. Heck , Irene Maria Antonia Nooren , Geert Plaetinck , Wendy T. Maddelein , Ty T. Vaughn
IPC分类号： C12N15/82 , C07H21/04 , C07K14/435 , C12N15/113
CPC分类号： C12N15/8286 , C07H21/04 , C07K14/43536 , C07K14/43563 , C12N15/113 , C12N15/8218 , C12N15/8282 , C12N15/8285 , Y02A40/146
摘要： The present invention relates to control of pest infestation by inhibiting one or more biological functions. The invention provides methods and compositions for such control, By feeding one or more recombinant double stranded RNA molecules provided by the invention to the pest, a reduction in pest infestation is obtained through suppression of gene expression. The invention is also directed to methods for making transgenic plants that express the double stranded RNA molecules, and to particular combinations of transgenic pesticidal agents for use in protecting plants from pest infestation.
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公开(公告)号：US20240076688A1
公开(公告)日：2024-03-07
申请号：US18488274
申请日：2023-10-17
发明人： JENNIFER KARA BARRY , CATHERINE J CLARK , RYAN MICHAEL GERBER , AMY LUM , JOHN P MATHIS , AZALEA S ONG , BROOKE PETERSON-BURCH , THOMAS CHAD WOLFE , WEIPING XIE , NASSER YALPANI , XIAOHONG ZHONG
IPC分类号： C12N15/82 , A01N37/46 , A01N63/50 , C07K14/415
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/50 , C07K14/415 , Y02A40/146
摘要： Compositions and methods for controlling pests are provided. The methods involve transforming organisms with a nucleic acid sequence encoding an insecticidal protein. In particular, the nucleic acid sequences are useful for preparing plants and microorganisms that possess insecticidal activity. Thus, transformed bacteria, plants, plant cells, plant tissues and seeds are provided. Compositions are insecticidal nucleic acids and proteins of bacterial species. The sequences find use in the construction of expression vectors for subsequent transformation into organisms of interest including plants, as probes for the isolation of other homologous (or partially homologous) genes. The pesticidal proteins find use in controlling, inhibiting growth or killing Lepidopteran, Coleopteran, Dipteran, fungal, Hemipteran and nematode pest populations and for producing compositions with insecticidal activity.
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公开(公告)号：US11905520B2
公开(公告)日：2024-02-20
申请号：US18052819
申请日：2022-11-04
IPC分类号： C12N15/82 , C12Q1/6895 , A01N37/46 , A01N63/50 , G01N33/53
CPC分类号： C12N15/8286 , A01N37/46 , A01N63/50 , C12Q1/6895 , C12Q2600/13 , G01N33/5308 , Y02A40/146 , A01N63/50 , A01N63/25
摘要： Pesticidal proteins exhibiting toxic activity against Lepidopteran pest species are disclosed, and include, but are not limited to, TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL. DNA constructs are provided which contain a recombinant nucleic acid sequence encoding one or more of the disclosed pesticidal proteins. Transgenic plants, plant cells, seed, and plant parts resistant to Lepidopteran infestation are provided which contain recombinant nucleic acid sequences encoding the pesticidal proteins of the present invention. Methods for detecting the presence of the recombinant nucleic acid sequences or the proteins of the present invention in a biological sample, and methods of controlling Lepidopteran species pests using any of the TIC6757, TIC6757PL, TIC7472, TIC7472PL, TIC7473, and TIC7473PL pesticidal proteins are also provided.
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公开(公告)号：US11884986B2
公开(公告)日：2024-01-30
申请号：US17819853
申请日：2022-08-15
IPC分类号： C12N15/82 , C12Q1/6895 , C07K14/415 , A23L7/10
CPC分类号： C12Q1/6895 , A23L7/10 , C07K14/415 , C12N15/8261 , C12Q2600/13 , C12Q2600/156 , C12Q2600/158 , Y02A40/146
摘要： The present disclosure provides a transgenic corn comprising event MON87403 that exhibits increased grain yield. The disclosure also provides cells, plant parts, seeds, plants, commodity products related to the event, and DNA molecules that are unique to the event and were created by the insertion of transgenic DNA into the genome of a corn plant. The disclosure further provides methods for detecting the presence of said corn event nucleotide sequences in a sample, probes and primers for use in detecting nucleotide sequences that are diagnostic for the presence of said corn event.
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