公开(公告)号：US20240301431A1

公开(公告)日：2024-09-12

申请号：US18020145

申请日：2021-10-05

Applicant: POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION

Inventor： Won Jong KIM ,  Jin Seong KIM ,  Hyeong Mok PARK

IPC: C12N15/115 ,  A61K9/51 ,  A61K47/69 ,  A61P27/02

CPC classification number: C12N15/115 ,  A61K9/513 ,  A61K47/6923 ,  A61K47/6929 ,  A61P27/02 ,  C12N2310/16

Abstract: The present disclosure relates to a polymer-coated gold nanoparticle-aptamer nanoconstruct having reactive oxygen species sensitivity and capable of treating inflammatory diseases through reactive oxygen species scavenge and TNF-α capture.