公开(公告)号：US10215762B2

公开(公告)日：2019-02-26

申请号：US15281829

申请日：2016-09-30

申请人： PROGENIKA BIOPHARMA, S.A.

发明人： Ainhoa Ruiz Del Agua ,  Antonio Martinez Martinez ,  Daniel Nagore Casas ,  Laureano Simon Buela

IPC分类号： A61K39/00 ,  C07K16/24 ,  G01N33/68 ,  G01N33/564 ,  G01N33/94 ,  A61K39/395 ,  A61K49/00 ,  G06F19/00

摘要： The invention relates to the field of personalized therapy and, in particular, to a method for classifying a patient suffering from rheumatoid arthritis as a responder or as a non-responder patient to a treatment based on a biological drug.

公开(公告)号：US20170102394A1

公开(公告)日：2017-04-13

申请号：US15281829

申请日：2016-09-30

申请人： PROGENIKA BIOPHARMA, S.A.

发明人： AINHOA RUIZ DEL AGUA ,  Antonio Martinez Martinez ,  Daniel Nagore Casas ,  Laureano Simon Buela

IPC分类号： G01N33/68 ,  G01N33/94 ,  G06F19/00 ,  C07K16/24

CPC分类号： G01N33/6893 ,  A61K39/3955 ,  A61K49/00 ,  C07K16/241 ,  C07K2317/21 ,  C07K2317/24 ,  G01N33/564 ,  G01N33/6854 ,  G01N33/9493 ,  G01N2333/525 ,  G01N2800/102 ,  G01N2800/24 ,  G01N2800/52 ,  G06F19/00 ,  G06F19/325 ,  G06F19/3468 ,  Y02A90/26

摘要： The invention relates to the field of personalized therapy and, in particular, to a method for classifying a patient suffering from rheumatoid arthritis as a responder or as a non-responder patient to a treatment based on a biological drug.

公开(公告)号：US10830779B2

公开(公告)日：2020-11-10

申请号：US15502733

申请日：2015-07-27

申请人： PROGENIKA BIOPHARMA, S.A.

发明人： Antonio Martinez Martinez ,  Daniel Nagore Casas ,  Alberto Monasterio Asteinza ,  Nerea Torres Antúnez

IPC分类号： G01N33/558 ,  G01N33/94 ,  G01N33/543 ,  G01N33/68

摘要： A lateral flow immunoassay for the detection of anti-drug antibodies against a biological drug includes a membrane having a capture area, a sample application area, a flow path from the sample application area to the capture area, and a conjugate area located in the flow path. The conjugate area has said biological drug detectably labeled and the capture area has said biological drug immobilized thereto.

公开(公告)号：US20160010160A1

公开(公告)日：2016-01-14

申请号：US14798101

申请日：2015-07-13

申请人： PROGENIKA BIOPHARMA, S.A.

发明人： Jokin del Amo ,  Diego Tejedor Hernandez ,  Antonio Martinez Martinez ,  Laureano Simon Buela ,  Juan Morote Robles

IPC分类号： C12Q1/68

CPC分类号： C12Q1/6886 ,  C12Q2600/106 ,  C12Q2600/118 ,  C12Q2600/156 ,  C12Q2600/158 ,  C12Q2600/16 ,  C12Q2600/172

摘要： A method for prognosing recurrence of prostate cancer (PCa) in a subject following prostatectomy using the outcomes of selected single nucleotide polymorphisms (SNPs) and clinical variables. A method for genotyping PCa associated genetic variations comprising use of a DNA microarray. A microarray for use in the described methods.

摘要翻译： 使用选择的单核苷酸多态性（SNP）和临床变量的结果预测前列腺切除术后受试者前列腺癌（PCa）复发的方法。 用于基因分型PCa相关遗传变异的方法，包括使用DNA微阵列。 用于所述方法的微阵列。