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公开(公告)号:US09534258B2
公开(公告)日:2017-01-03
申请号:US14472755
申请日:2014-08-29
CPC分类号: C12Q1/6886 , C12Q2600/118 , C12Q2600/158 , C12Q2600/16 , G06F19/00 , G16H50/30
摘要: The invention relates to prognostic markers and prognostic signatures, and compositions and methods for determining the prognosis of cancer in a patient, particularly for melanoma. Specifically, the invention relates to the use of genetic and protein markers for the prediction of the risk of progression of a cancer, such as melanoma, based on markers and signatures of markers. In various aspects, the invention provides methods, compositions, kits, and devices based on prognostic cancer markers, specifically melanoma prognostic markers, to aid in the prognosis and treatment of cancer.
摘要翻译: 本发明涉及预后标志物和预后特征,以及用于确定患者中癌症预后的组合物和方法,特别是对于黑素瘤。 具体而言,本发明涉及遗传和蛋白质标记物用于基于标记物和标记物的标记来预测癌症进展风险(例如黑素瘤)的用途。 在各个方面,本发明提供了基于预后癌症标志物,特别是黑素瘤预后标志物的方法,组合物,试剂盒和装置,以帮助癌症的预后和治疗。