利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

4 条记录 (耗时 0.022 秒)

    SOLID FORMULATIONS OF LIQUID BIOLOGICALLY ACTIVE AGENTS
    1.
    发明申请
    SOLID FORMULATIONS OF LIQUID BIOLOGICALLY ACTIVE AGENTS 审中-公开
    液体生物活性剂的固体制剂

    公开(公告)号：US20160193341A1

    公开(公告)日：2016-07-07

    申请号：US14844493

    申请日：2015-09-03

    申请人： Paladin Labs Inc. ,  Paladin Labs Europe Limited ,  Paladin Labs (Barbados) Inc.

    发明人： Francois Ravenelle ,  Sandra Gori ,  David Lessard ,  Laibin Luo ,  Dorothee Le Garrec ,  Damon Smith

    IPC分类号： A61K47/34 ,  A61K9/107 ,  A61K31/05 ,  B01F3/08 ,  A61J3/02 ,  A61K31/085 ,  A61K31/47 ,  A61K9/00 ,  A61K9/19

    摘要： The instant invention relates to a solid product comprising a liquid biologically active agent which is intimately associated to a stabilizing agent; particularly a solid product that can be reconstituted to a clear, stable, stabilized nanodispersion or loaded micelles comprising a polymer as a stabilizing agent and a liquid, preferably water immiscible, biologically active agent. The instant invention is further directed toward a process for the production of the above solid product; particularly to micelles or nanodispersions produced by hydration of a cake or powder of the solid product, produced via an effective treatment of a stabilized solution comprising for example a polymer as a stabilizing agent, such as an amphiphilic block copolymer or a small molecular weight surfactant, loaded with a liquid biologically active agent, such as propofol, an optional additive, and a suitable solvent.

    摘要翻译： 本发明涉及包含与稳定剂紧密结合的液体生物活性剂的固体产品; 特别是可以重构为透明，稳定，稳定的纳米分散体或负载胶束的固体产物，其包含作为稳定剂的聚合物和液体，优选与水不混溶的生物活性剂。 本发明进一步涉及生产上述固体产品的方法; 特别是通过有效处理包含例如作为稳定剂的聚合物如两亲性嵌段共聚物或小分子量表面活性剂的稳定溶液产生的固体产物的饼或粉末的水合产生的胶束或纳米分散体， 装载有液体生物活性剂，例如丙泊酚，任选的添加剂和合适的溶剂。

    SOLID FORMULATIONS OF LIQUID BIOLOGICALLY ACTIVE AGENTS
    2.
    发明申请
    SOLID FORMULATIONS OF LIQUID BIOLOGICALLY ACTIVE AGENTS 审中-公开
    液体生物活性剂的固体制剂

    公开(公告)号：US20140323587A1

    公开(公告)日：2014-10-30

    申请号：US14134156

    申请日：2013-12-19

    申请人： Paladin Labs Inc. ,  Paladin Labs (Barbados)Inc. ,  Paladin Labs Europe Limited

    发明人： Francois Ravenelle ,  Sandra Gori ,  David Lessard ,  Laibin Luo ,  Dorothee Le Garrec ,  Damon Smith

    IPC分类号： A61K31/05

    摘要： The instant invention relates to a solid product comprising a liquid biologically active agent which is intimately associated to a stabilizing agent; particularly a solid product that can be reconstituted to a clear, stable, stabilized nanodispersion or loaded micelles comprising a polymer as a stabilizing agent and a liquid, preferably water immiscible, biologically active agent. The instant invention is further directed toward a process for the production of the above solid product; particularly to micelles or nanodispersions produced by hydration of a cake or powder of the solid product, produced via an effective treatment of a stabilized solution comprising for example a polymer as a stabilizing agent, such as an amphiphilic block copolymer or a small molecular weight surfactant, loaded with a liquid biologically active agent, such as propofol, an optional additive, and a suitable solvent.

    摘要翻译： 本发明涉及包含与稳定剂紧密结合的液体生物活性剂的固体产品; 特别是可以重构为透明，稳定，稳定的纳米分散体或负载胶束的固体产物，其包含作为稳定剂的聚合物和液体，优选与水不混溶的生物活性剂。 本发明进一步涉及生产上述固体产品的方法; 特别是通过有效处理包含例如作为稳定剂的聚合物如两亲性嵌段共聚物或小分子量表面活性剂的稳定溶液产生的固体产物的饼或粉末的水合产生的胶束或纳米分散体， 装载有液体生物活性剂，例如丙泊酚，任选的添加剂和合适的溶剂。