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公开(公告)号:US20070168135A1
公开(公告)日:2007-07-19
申请号:US10562096
申请日:2004-06-22
申请人: Pankaj Agarwal , William Reisdorf Jr , Sujoy Ghosh , Vinod Kumar , Mark Hurle , Karen Kabnick , Paul McAllister , David Searls , Kay Tatsuoka , Liwen Liu , Michal Magid-Slav , Dmitri Zaykin
发明人: Pankaj Agarwal , William Reisdorf Jr , Sujoy Ghosh , Vinod Kumar , Mark Hurle , Karen Kabnick , Paul McAllister , David Searls , Kay Tatsuoka , Liwen Liu , Michal Magid-Slav , Dmitri Zaykin
IPC分类号: G06F19/00
摘要: A method of identifying a relationship between a set of one or more candidate biomolecules and a set of one or more reference biomolecules, the method including inputting to a computer a query set describing the one or more candidate biomolecules; comparing the query set with a target database describing the one or more reference biomolecules wherein the one or more reference biomolecules grouped into one or more buckets and wherein the one or more reference biomolecules of each bucket share a common property; counting a number of matches between each query set and each buckets of the target database; and statistically analyzing the number of matches to each bucket wherein the presence of a statistically significant match identifies a relationship between a the query set and a bucket of the target database.
摘要翻译: 一种识别一组一个或多个候选生物分子与一组或多个参考生物分子之间的关系的方法,所述方法包括向计算机输入描述所述一个或多个候选生物分子的查询集; 将所述查询集与描述所述一个或多个参考生物分子的目标数据库进行比较,其中所述一个或多个参考生物分子分组成一个或多个桶,并且其中每个桶的一个或多个参考生物分子共享共同性质; 计算每个查询集与目标数据库的每个桶之间的匹配数; 并且统计分析与每个桶的匹配数量,其中存在统计学显着的匹配标识了所述查询集和所述目标数据库的桶之间的关系。