专利检索 ap:("Pardes Biosciences, Inc.") AND inv:"Dange Vijay Kumar" 第 1 页

1.

发明公开
INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF 审中-公开

公开(公告)号：US20240277795A1

公开(公告)日：2024-08-22

申请号：US18444009

申请日：2024-02-16

申请人： Pardes Biosciences, Inc.

发明人： Daniel J. Buzard , Walter Keung , Dange Vijay Kumar , Erik Verner , Lee D. Arnold

IPC分类号： A61K38/05 , A61K45/06 , A61P31/14 , C07K1/107

CPC分类号： A61K38/05 , A61K45/06 , A61P31/14 , C07K1/1077

摘要： The disclosure provides compounds with nitrile warheads and their use in treating medical diseases or disorders, such as viral infections. Pharmaceutical compositions and methods of making various compounds with nitrile warheads are provided. The compounds are contemplated to inhibit proteases, such as the 3C, CL- or 3CL-like protease.