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公开(公告)号：US20080076112A1
公开(公告)日：2008-03-27
申请号：US11858737
申请日：2007-09-20
CPC分类号： G01N33/6887
摘要： For successful wound healing to occur, the newly formed skin must generate tensile strength through collagen deposition. Measurement of collagen in the granulating wound bed may be predictive of successful wound healing. Existing methods for collagen measurement either require specialized equipment, or do not allow for discrimination of potential interfering molecules. Herein described is an accurate, specific and reliable method to extract and quantify collagen from tissue utilizing high pressure liquid chromatography techniques. The method is sensitive enough to measure the small amounts of collagen found in newly healing wounds.
摘要翻译： 对于成功的伤口愈合发生，新形成的皮肤必须通过胶原沉积产生拉伸强度。 造粒伤口床中的胶原蛋白的测量可预示成功伤口愈合。 用于胶原测量的现有方法需要专门的设备，或者不允许区分潜在的干扰分子。 本文描述了使用高压液相色谱技术从组织中提取和定量胶原蛋白的准确，具体和可靠的方法。 该方法足够灵敏以测量新愈合伤口发现的少量胶原蛋白。
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公开(公告)号：US07713743B2
公开(公告)日：2010-05-11
申请号：US12367729
申请日：2009-02-09
IPC分类号： G01N1/28
CPC分类号： G01N33/6887
摘要： For successful wound healing to occur, the newly formed skin must generate tensile strength through collagen deposition. Measurement of collagen in the granulating wound bed may be predictive of successful wound healing. Existing methods for collagen measurement either require specialized equipment, or do not allow for discrimination of potential interfering molecules. Herein described is an accurate, specific and reliable method to extract and quantify collagen from tissue utilizing high pressure liquid chromatography techniques. The method is sensitive enough to measure the small amounts of collagen found in newly healing wounds.
摘要翻译： 对于成功的伤口愈合发生，新形成的皮肤必须通过胶原沉积产生拉伸强度。 造粒伤口床中的胶原蛋白的测量可预示成功伤口愈合。 用于胶原测量的现有方法需要专门的设备，或者不允许区分潜在的干扰分子。 本文描述了使用高压液相色谱技术从组织中提取和定量胶原蛋白的准确，具体和可靠的方法。 该方法足够灵敏以测量新愈合伤口发现的少量胶原蛋白。
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公开(公告)号：US20090142799A1
公开(公告)日：2009-06-04
申请号：US12367729
申请日：2009-02-09
IPC分类号： G01N1/28
CPC分类号： G01N33/6887
摘要： For successful wound healing to occur, the newly formed skin must generate tensile strength through collagen deposition. Measurement of collagen in the granulating wound bed may be predictive of successful wound healing. Existing methods for collagen measurement either require specialized equipment, or do not allow for discrimination of potential interfering molecules. Herein described is an accurate, specific and reliable method to extract and quantify collagen from tissue utilizing high pressure liquid chromatography techniques. The method is sensitive enough to measure the small amounts of collagen found in newly healing wounds.
摘要翻译： 对于成功的伤口愈合发生，新形成的皮肤必须通过胶原沉积产生拉伸强度。 造粒伤口床中的胶原蛋白的测量可预示成功伤口愈合。 用于胶原测量的现有方法需要专门的设备，或者不允许区分潜在的干扰分子。 本文描述了使用高压液相色谱技术从组织中提取和定量胶原蛋白的准确，具体和可靠的方法。 该方法足够灵敏以测量新愈合伤口发现的少量胶原蛋白。
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公开(公告)号：US07491541B2
公开(公告)日：2009-02-17
申请号：US11858737
申请日：2007-09-20
CPC分类号： G01N33/6887
摘要： For successful wound healing to occur, the newly formed skin must generate tensile strength through collagen deposition. Measurement of collagen in the granulating wound bed may be predictive of successful wound healing. Existing methods for collagen measurement either require specialized equipment, or do not allow for discrimination of potential interfering molecules. Herein described is an accurate, specific and reliable method to extract and quantify collagen from tissue utilizing high pressure liquid chromatography techniques. The method is sensitive enough to measure the small amounts of collagen found in newly healing wounds.
摘要翻译： 对于成功的伤口愈合发生，新形成的皮肤必须通过胶原沉积产生拉伸强度。 造粒伤口床中的胶原蛋白的测量可预示成功伤口愈合。 用于胶原测量的现有方法需要专门的设备，或者不允许区分潜在的干扰分子。 本文描述了使用高压液相色谱技术从组织中提取和定量胶原蛋白的准确，具体和可靠的方法。 该方法足够灵敏以测量新愈合伤口发现的少量胶原蛋白。
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公开(公告)号：US07981668B2
公开(公告)日：2011-07-19
申请号：US11624017
申请日：2007-01-17
IPC分类号： C12M3/00
摘要： A method and system for culturing cells, having a substantially airtight enclosure configured to culture cells. The method and system also have a first conduit configured to provide a reduced pressure to the substantially airtight enclosure and a second conduit configured to provide a culture media to the substantially airtight enclosure.
摘要翻译： 用于培养细胞的方法和系统，其具有构造成培养细胞的基本上气密的外壳。 所述方法和系统还具有构造成向基本上气密的外壳提供减压的第一导管和被配置为向基本上气密的外壳提供培养基的第二导管。
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公开(公告)号：US20130245386A1
公开(公告)日：2013-09-19
申请号：US13869433
申请日：2013-04-24
IPC分类号： A61K49/00
CPC分类号： A61K49/0006 , G01N33/52 , G01N33/56966 , G01N2510/00
摘要： Provided are methods of determining whether a cell in a tissue site is viable or nonviable. Also provided are methods of debriding tissue from a tissue site. Further provided are kits comprising a compound that distinguishes between viable and nonviable cells and instructions for using the compound on a tissue site. Additionally, the use of a compound that distinguishes between viable and nonviable cells is provided, where the use is to determine whether a cell in a tissue site is viable or nonviable. Also provided is a use of a compound that distinguishes between viable and nonviable cells, where the use is for the manufacture of the above-described kit.
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公开(公告)号：US20070166817A1
公开(公告)日：2007-07-19
申请号：US11624017
申请日：2007-01-17
IPC分类号： C12M1/12
摘要： A method and system for culturing cells, having a substantially airtight enclosure configured to culture cells. The method and system also have a first conduit configured to provide a reduced pressure to the substantially airtight enclosure and a second conduit configured to provide a culture media to the substantially airtight enclosure.
摘要翻译： 用于培养细胞的方法和系统，其具有构造成培养细胞的基本上气密的外壳。 所述方法和系统还具有构造成向基本上气密的外壳提供减压的第一导管和被配置为向基本上气密的外壳提供培养基的第二导管。
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公开(公告)号：US20130053793A1
公开(公告)日：2013-02-28
申请号：US13588747
申请日：2012-08-17
CPC分类号： A61M1/0088 , A61M1/0031 , A61M1/3687 , A61M27/00 , Y10T137/0402
摘要： A reduced-pressure treatment system for debriding a treatment area of a tissue site and applying reduced pressure is disclosed. The reduced-pressure treatment system includes a hydrogel having a blocked acid debriding agent. The hydrogel is adapted to cover the treatment area and enhance autolytic debridement at the treatment area. The reduced-pressure treatment system includes a manifold that is adapted to cover the hydrogel and distribute reduced pressure to the tissue site. The reduced-pressure treatment system also includes a sealing drape for forming a fluid seal over the tissue site and manifold. Other systems, methods, and dressings are presented.
摘要翻译： 公开了一种用于清除组织部位的治疗区域并施加减压的减压治疗系统。 减压处理系统包括具有封闭的酸清除剂的水凝胶。 水凝胶适用于治疗区域，增强治疗区域的自溶清创。 减压治疗系统包括适于覆盖水凝胶并将减压分布到组织部位的歧管。 减压处理系统还包括用于在组织部位和歧管上形成流体密封的密封盖。 介绍了其他系统，方法和敷料。
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公开(公告)号：US20100196905A1
公开(公告)日：2010-08-05
申请号：US12694932
申请日：2010-01-27
申请人： Amy K. McNulty , Kathleen L. Derrick , Diwi Allen
发明人： Amy K. McNulty , Kathleen L. Derrick , Diwi Allen
CPC分类号： C12Q1/6881 , C12Q2600/158
摘要： Provided are methods for quantifying adult stem cells in a test sample, methods of quantifying adult stem cells in a patient, and methods for quantifying differentiated cells in a test sample. Also provided are kits for quantifying adult stem cells or differentiated cells in a sample.
摘要翻译： 提供了在测试样品中量化成体干细胞的方法，定量患者中成体干细胞的方法以及在测试样品中定量分化细胞的方法。 还提供了用于定量样品中成体干细胞或分化细胞的试剂盒。
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公开(公告)号：US10172984B2
公开(公告)日：2019-01-08
申请号：US13588747
申请日：2012-08-17
摘要： A reduced-pressure treatment system for debriding a treatment area of a tissue site and applying reduced pressure is disclosed. The reduced-pressure treatment system includes a hydrogel having a blocked acid debriding agent. The hydrogel is adapted to cover the treatment area and enhance autolytic debridement at the treatment area. The reduced-pressure treatment system includes a manifold that is adapted to cover the hydrogel and distribute reduced pressure to the tissue site. The reduced-pressure treatment system also includes a sealing drape for forming a fluid seal over the tissue site and manifold. Other systems, methods, and dressings are presented.
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