公开(公告)号：US08706190B2

公开(公告)日：2014-04-22

申请号：US12943381

申请日：2010-11-10

申请人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland ,  Rares Salomir

发明人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland ,  Rares Salomir

IPC分类号： A61B5/05

CPC分类号： G01R33/4804 ,  G01R33/56536

摘要： In a method or system for magnetic resonance imaging based temperature monitoring for real-time feedback to a physician for a cryoablation therapy of a lesion which creates an ice ball of the lesion to induce cell death, the magnetic resonance imaging system, using proton resonance frequency imaging, obtains a real-time temperature image of the ice ball of the lesion undergoing the cryoablation therapy and the adjacent surrounding tissue. By use of an algorithm, correcting temperature errors at a border of the ice ball are corrected in the real-time image, the temperature error correction correcting susceptibility contrast errors caused by a distortion of the local magnetic field at the border of the ice ball.

摘要翻译： 在用于基于磁共振成像的温度监测的方法或系统中，用于实时反馈给医师进行冷冻消融治疗病变，其产生损伤的冰球以诱导细胞死亡，磁共振成像系统使用质子共振频率 成像，获得经历冷冻消融治疗的病变的冰球和相邻的周围组织的实时温度图像。 通过使用算法，在实时图像中校正冰球边界处的温度误差，由冰球边界处的局部磁场的失真引起的温度误差校正矫正磁敏度对比度误差。

公开(公告)号：US08710840B2

公开(公告)日：2014-04-29

申请号：US13216505

申请日：2011-08-24

申请人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland

发明人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland

IPC分类号： G01V3/00

CPC分类号： G01R33/565 ,  G01R33/50 ,  G01R33/5611 ,  G01R33/5615 ,  G01R33/56536 ,  G01R33/56563

摘要： In a method and system for phase-sensitive magnetic resonance imaging, a respective, complex image data set provided to a processor for each of at least two different echo times, the complex image data sets for the different echo times having been reconstructed from magnetic resonance data that acquired for the different echo times using an echo imaging sequence, at least one complex division image data set is determined in the processor by complex division of the complex image data sets for the two different echo times. The two different echo times define an echo time difference, so the resulting complex division image data set has phase components that are dependent on the echo time difference.

摘要翻译： 在用于相敏磁共振成像的方法和系统中，为至少两个不同回波时间中的每一个提供给处理器的相应复杂图像数据组，用于不同回波时间的复数图像数据集已经从磁共振 使用回波成像序列为不同回波时间获取的数据，通过对于两个不同回波时间的复数图像数据集的复杂划分，在处理器中确定至少一个复分割图像数据集。 两个不同的回波时间定义了回波时间差，因此所得到的复数分割图像数据集具有取决于回波时间差的相位分量。

公开(公告)号：US20120068703A1

公开(公告)日：2012-03-22

申请号：US13239643

申请日：2011-09-22

申请人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland

发明人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland

IPC分类号： G01R33/48 ,  G01R33/36

CPC分类号： G01R33/50 ,  G01R33/5611 ,  G01R33/5615 ,  G01R33/565 ,  G01R33/56536 ,  G01R33/56563

摘要： In a magnetic resonance (MR) method and apparatus for spatially resolved determination of at least one MR parameter that influences an MR signal detected in an MR measurement of a region of an examination subject, first complex image data and second complex image data, respectively acquired with different acquisition coils and at different echo times in an echo imaging sequence, are provided to a processor. The different image data sets have complex image points that correspond with each other with regard to the imaged volume element of the examination subject. The MR parameter is determined in the processor for at least a portion of these image points by determination of an image point vector respectively for the first and second echo times and by combining the image point vectors to at least partially compensate echo time-independent phase or magnitude portions in the acquired image data.

摘要翻译： 在磁共振（MR）方法和装置中，用于空间分辨确定影响检查对象区域的MR测量中检测到的MR信号的至少一个MR参数，分别获取第一复数图像数据和第二复数图像数据 具有不同的采集线圈和在回波成像序列中的不同回波时间，被提供给处理器。 不同的图像数据组具有相对于检查对象的成像体积元素彼此对应的复杂图像点。 通过对于第一和第二回波时间分别确定图像点矢量并且通过组合图像点向量来至少部分地补偿回波时间无关相位或者对于第一和第二回波时间的至少一部分来确定MR参数， 获取的图像数据中的大小部分。

公开(公告)号：US20120049846A1

公开(公告)日：2012-03-01

申请号：US13216505

申请日：2011-08-24

申请人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland

发明人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland

IPC分类号： G01R33/48

CPC分类号： G01R33/565 ,  G01R33/50 ,  G01R33/5611 ,  G01R33/5615 ,  G01R33/56536 ,  G01R33/56563

摘要： In a method and system for phase-sensitive magnetic resonance imaging, a respective, complex image data set provided to a processor for each of at least two different echo times, the complex image data sets for the different echo times having been reconstructed from magnetic resonance data that acquired for the different echo times using an echo imaging sequence, at least one complex division image data set is determined in the processor by complex division of the complex image data sets for the two different echo times. The two different echo times define an echo time difference, so the resulting complex division image data set has phase components that are dependent on the echo time difference.

摘要翻译： 在用于相敏磁共振成像的方法和系统中，为至少两个不同回波时间中的每一个提供给处理器的相应复杂图像数据组，用于不同回波时间的复数图像数据集已经从磁共振 使用回波成像序列为不同回波时间获取的数据，通过对于两个不同回波时间的复数图像数据集的复杂划分，在处理器中确定至少一个复分割图像数据集。 两个不同的回波时间定义了回波时间差，因此所得到的复数分割图像数据集具有取决于回波时间差的相位分量。

公开(公告)号：US08754645B2

公开(公告)日：2014-06-17

申请号：US13239643

申请日：2011-09-22

申请人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland

发明人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland

IPC分类号： G01V3/00

CPC分类号： G01R33/50 ,  G01R33/5611 ,  G01R33/5615 ,  G01R33/565 ,  G01R33/56536 ,  G01R33/56563

摘要： In a magnetic resonance (MR) method and apparatus for spatially resolved determination of at least one MR parameter that influences an MR signal detected in an MR measurement of a region of an examination subject, first complex image data and second complex image data, respectively acquired with different acquisition coils and at different echo times in an echo imaging sequence, are provided to a processor. The different image data sets have complex image points that correspond with each other with regard to the imaged volume element of the examination subject. The MR parameter is determined in the processor for at least a portion of these image points by determination of an image point vector respectively for the first and second echo times and by combining the image point vectors to at least partially compensate echo time-independent phase or magnitude portions in the acquired image data.

摘要翻译： 在磁共振（MR）方法和装置中，用于空间分辨确定影响检查对象区域的MR测量中检测到的MR信号的至少一个MR参数，分别获取第一复数图像数据和第二复数图像数据 具有不同的采集线圈和在回波成像序列中的不同回波时间，被提供给处理器。 不同的图像数据组具有相对于检查对象的成像体积元素彼此对应的复杂图像点。 通过对于第一和第二回波时间分别确定图像点矢量并且通过组合图像点向量来至少部分地补偿回波时间无关相位或者对于第一和第二回波时间的至少一部分来确定MR参数， 获取的图像数据中的大小部分。

公开(公告)号：US20120116208A1

公开(公告)日：2012-05-10

申请号：US12943381

申请日：2010-11-10

申请人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland ,  Rares Salomir

发明人： Patrick Gross ,  Antje Kickhefel ,  Joerg Roland ,  Rares Salomir

IPC分类号： A61B5/055

CPC分类号： G01R33/4804 ,  G01R33/56536

摘要： In a method or system for magnetic resonance imaging based temperature monitoring for real-time feedback to a physician for a cryoablation therapy of a lesion which creates an ice ball of the lesion to induce cell death, the magnetic resonance imaging system, using proton resonance frequency imaging, obtains a real-time temperature image of the ice ball of the lesion undergoing the cryoablation therapy and the adjacent surrounding tissue. By use of an algorithm, correcting temperature errors at a border of the ice ball are corrected in the real-time image, the temperature error correction correcting susceptibility contrast errors caused by a distortion of the local magnetic field at the border of the ice ball.

摘要翻译： 在用于基于磁共振成像的温度监测的方法或系统中，用于实时反馈给医师进行冷冻消融治疗病变，其产生损伤的冰球以诱导细胞死亡，磁共振成像系统使用质子共振频率 成像，获得经历冷冻消融治疗的病变的冰球和相邻的周围组织的实时温度图像。 通过使用算法，在实时图像中校正冰球边界处的温度误差，由冰球边界处的局部磁场的失真引起的温度误差校正矫正磁敏度对比度误差。

公开(公告)号：US20120092011A1

公开(公告)日：2012-04-19

申请号：US13273450

申请日：2011-10-14

申请人： Antje Kickhefel ,  Joerg Roland ,  Eva Rothgang

发明人： Antje Kickhefel ,  Joerg Roland ,  Eva Rothgang

IPC分类号： G01R33/48 ,  G01R33/34

CPC分类号： G01R33/4804 ,  G01R33/56308 ,  G01R33/56341 ,  G01R33/56509

摘要： In a magnetic resonance method and system to determine a position of a slice relative to a region moving relative to the slice within a predetermined volume segment of an examination subject located in the magnetic resonance system, a physical property within the slice is detected with spatial resolution at multiple points in time, such that a time curve of the physical property is detected for at least one voxel of the slice. The position of the slice relative to the region is determined with respect to defined points in time, depending on the time curve.

摘要翻译： 在磁共振方法和系统中，确定切片相对于位于磁共振系统中的检查对象的预定体积段内相对于切片移动的区域的位置，利用空间分辨率检测切片内的物理特性 在多个时间点，使得对于切片的至少一个体素检测物理性质的时间曲线。 根据时间曲线，相对于定义的时间点确定切片相对于该区域的位置。

公开(公告)号：US09000765B2

公开(公告)日：2015-04-07

申请号：US13273450

申请日：2011-10-14

申请人： Antje Kickhefel ,  Joerg Roland ,  Eva Rothgang

发明人： Antje Kickhefel ,  Joerg Roland ,  Eva Rothgang

IPC分类号： G01R33/48 ,  G01R33/34 ,  G01R33/565 ,  G01R33/563

CPC分类号： G01R33/4804 ,  G01R33/56308 ,  G01R33/56341 ,  G01R33/56509

摘要： In a magnetic resonance method and system to determine a position of a slice relative to a region moving relative to the slice within a predetermined volume segment of an examination subject located in the magnetic resonance system, a physical property within the slice is detected with spatial resolution at multiple points in time, such that a time curve of the physical property is detected for at least one voxel of the slice. The position of the slice relative to the region is determined with respect to defined points in time, depending on the time curve.

摘要翻译： 在磁共振方法和系统中，确定切片相对于位于磁共振系统中的检查对象的预定体积段内相对于切片移动的区域的位置，利用空间分辨率检测切片内的物理特性 在多个时间点，使得对于切片的至少一个体素检测物理性质的时间曲线。 根据时间曲线，相对于定义的时间点确定切片相对于该区域的位置。

公开(公告)号：US20110176714A1

公开(公告)日：2011-07-21

申请号：US12970184

申请日：2010-12-16

申请人： Rares Salomir ,  Magalie Viallon ,  Joerg Roland ,  Patrick Gross

发明人： Rares Salomir ,  Magalie Viallon ,  Joerg Roland ,  Patrick Gross

IPC分类号： G06K9/00

CPC分类号： G01R33/4804 ,  G01R33/56509

摘要： In a method to determine a background phase in phase values of a phase image data set that is acquired from an examination subject, wherein the background phase is determined in a partial region of the phase image data set, the phase image data set of the examination subject is acquired, and a substantially closed, planar contour is established in the phase image data set around the partial region, the planar contour having a contour area with a width of at least one pixel of the phase image data set. The phase values in the partial region are determined with the assumption that the spatial curve of the background phase is a harmonic or quasi-harmonic function, the phase values of the pixels in the partial region being determined based on the phase values in the planar contour.

摘要翻译： 在确定从检查对象获取的相位图像数据集的相位值的背景相位的方法中，其中在相位图像数据集的部分区域中确定背景相位，检查的相位图像数据集 获取对象，并且在围绕该部分区域设置的相位图像数据中建立基本封闭的平面轮廓，该平面轮廓具有具有相位图像数据集的至少一个像素的宽度的轮廓区域。 通过假设背景相位的空间曲线是谐波或准谐波函数来确定部分区域中的相位值，基于平面轮廓中的相位值来确定部分区域中的像素的相位值 。

公开(公告)号：US08630471B2

公开(公告)日：2014-01-14

申请号：US12970184

申请日：2010-12-16

申请人： Rares Salomir ,  Magalie Viallon ,  Joerg Roland ,  Patrick Gross

发明人： Rares Salomir ,  Magalie Viallon ,  Joerg Roland ,  Patrick Gross

IPC分类号： G06K9/00

CPC分类号： G01R33/4804 ,  G01R33/56509

摘要： In a method to determine a background phase in phase values of a phase image data set that is acquired from an examination subject, wherein the background phase is determined in a partial region of the phase image data set, the phase image data set of the examination subject is acquired, and a substantially closed, planar contour is established in the phase image data set around the partial region, the planar contour having a contour area with a width of at least one pixel of the phase image data set. The phase values in the partial region are determined with the assumption that the spatial curve of the background phase is a harmonic or quasi-harmonic function, the phase values of the pixels in the partial region being determined based on the phase values in the planar contour.

摘要翻译： 在确定从检查对象获取的相位图像数据集的相位值的背景相位的方法中，其中在相位图像数据集的部分区域中确定背景相位，检查的相位图像数据集 获取对象，并且在围绕该部分区域设置的相位图像数据中建立基本封闭的平面轮廓，该平面轮廓具有具有相位图像数据集的至少一个像素的宽度的轮廓区域。 通过假设背景相位的空间曲线是谐波或准谐波函数来确定部分区域中的相位值，基于平面轮廓中的相位值来确定部分区域中的像素的相位值 。