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公开(公告)号：US5667804A
公开(公告)日：1997-09-16
申请号：US671226
申请日：1996-06-27
CPC分类号： A61K9/2072
摘要： The present invention is directed to an active agent dosage form which is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has on its surface two or more insoluble bands. The invention is also directed to the method for making the active agent dosage form.
摘要翻译： 本发明涉及一种活性剂剂型，其可用于将活性剂制剂延长递送至使用的流体环境。 活性剂剂型是其表面上具有两个或多个不溶性带的基质。 本发明还涉及制备活性剂剂型的方法。
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公开(公告)号：US06316028B1
公开(公告)日：2001-11-13
申请号：US09652655
申请日：2000-08-31
IPC分类号： A61K924
CPC分类号： A61K9/2072
摘要： The present invention is directed to an active agent dosage that is useful for the prolonged delivery of an active agent formulation to fluid environment of use. The active agent dosage form is a matrix that has an insoluble material circumscribing a portion of the surface of the matrix. The invention is also directed to a method of making the active agent dosage form.
摘要翻译： 本发明涉及可用于将活性剂制剂延长递送至使用的流体环境的活性剂剂量。 活性剂剂型是具有包围基质表面的一部分的不溶性物质的基质。 本发明还涉及制备活性剂剂型的方法。
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公开(公告)号：US6020000A
公开(公告)日：2000-02-01
申请号：US149042
申请日：1998-09-08
CPC分类号： A61K9/2072
摘要： The present invention is directed to an active agent dosage form that is useful for the prolonged delivery of an active agent formulation to a fluid environment of use. The active agent dosage form is a matrix that has an insoluble material circumscribing a portion of the surface of the matrix. The invention is also directed to a method of making the active agent dosage form.
摘要翻译： 本发明涉及可用于将活性剂制剂延长递送至使用的流体环境的活性剂剂型。 活性剂剂型是具有包围基质表面的一部分的不溶性物质的基质。 本发明还涉及制备活性剂剂型的方法。
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公开(公告)号：US06551613B1
公开(公告)日：2003-04-22
申请号：US09353519
申请日：1999-07-14
IPC分类号： A61K948
CPC分类号： A61K9/0004
摘要： A dosage form is disclosed comprising a semipermeable walled container that houses a capsule, which capsule comprises a drug formulation, a piston, and an osmotic composition. The dosage form delivers the drug formulation through a passageway at a controlled rate over a sustained-release period of time up to 24 hours.
摘要翻译： 公开了一种剂型，其包含容纳胶囊的半透性壁容器，该胶囊包括药物制剂，活塞和渗透组合物。 该剂型在持续释放的时间长达24小时内以可控的速率通过通道递送药物制剂。
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公开(公告)号：US20080181944A1
公开(公告)日：2008-07-31
申请号：US12060885
申请日：2008-04-02
IPC分类号： A61K9/52 , A61K31/57 , A61K31/522
CPC分类号： A61K9/0004
摘要： A dosage form is disclosed comprising a semipermeable walled container that houses a capsule, which capsule comprises a drug formulation, a piston, and an osmotic composition. The dosage form delivers the drug formulation through a passageway at a controlled rate over a sustained-release period of time up to 24 hours.
摘要翻译： 公开了一种剂型，其包含容纳胶囊的半透性壁容器，该胶囊包括药物制剂，活塞和渗透组合物。 该剂型在持续释放的时间长达24小时内以可控的速率通过通道递送药物制剂。
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公开(公告)号：US20090130204A1
公开(公告)日：2009-05-21
申请号：US12359235
申请日：2009-01-23
IPC分类号： A61K9/52
CPC分类号： A61K9/0004
摘要： A dosage form is disclosed comprising a semipermeable walled container that houses a capsule, which capsule comprises a drug formulation, a piston, and an osmotic composition. The dosage form delivers the drug formulation through a passageway at a controlled rate over a sustained-release period of time up to 24 hours.
摘要翻译： 公开了一种剂型，其包含容纳胶囊的半透性壁容器，该胶囊包括药物制剂，活塞和渗透组合物。 该剂型在持续释放的时间长达24小时内以可控的速率通过通道递送药物制剂。
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公开(公告)号：US20100159002A1
公开(公告)日：2010-06-24
申请号：US12716185
申请日：2010-03-02
CPC分类号： A61K9/0004
摘要： A dosage form is disclosed comprising a semipermeable walled container that houses a capsule, which capsule comprises a drug formulation, a piston, and an osmotic composition. The dosage form delivers the drug formulation through a passageway at a controlled rate over a sustained-release period of time up to 24 hours.
摘要翻译： 公开了一种剂型，其包含容纳胶囊的半透性壁容器，该胶囊包括药物制剂，活塞和渗透组合物。 该剂型在持续释放的时间长达24小时内以可控的速率通过通道递送药物制剂。
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