中科微点-全球专利检索

  1. Login
  2. Sign Up

Search Results

36 records (took 0.019 seconds)

    Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine
    3.
    发明授权
    Methods and compositions for treating allergic asthma and dermatitis using descarboethoxyloratadine 失效
    使用去甲氧基乙酰氨喋呤治疗过敏性哮喘和皮炎的方法和组合物

    公开(公告)号：US5900421A

    公开(公告)日：1999-05-04

    申请号：US799605

    申请日：1997-02-11

    Applicant: Dean A. Handley ,  Paul D. Rubin

    Inventor： Dean A. Handley ,  Paul D. Rubin

    IPC: A61K31/445 ,  A61K31/4545 ,  A61K45/06 ,  A61P11/06 ,  A61P37/08 ,  A61P43/00 ,  A61K31/44

    CPC classification number: A61K45/06 ,  A61K31/445 ,  A61K31/4545 ,  Y10S514/826 ,  Y10S514/864

    Abstract: Methods utilizing descarboethoxyloratadine ("DCL"), for the treatment of allergic disorders, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. Also included are methods for the treatment of allergic asthma using DCL and either a decongestant or a leukotriene inhibitor, while avoiding the concomitant liability of adverse side-effects associated with other non-sedating antihistamines. The invention also encompasses the administration of DCL in a nasal or oral spray.

    Abstract translation: 利用去甲氧基吡咯烷（“DCL”）治疗过敏性疾病的方法，同时避免与其他非镇静性抗组胺药相关的不利副作用的伴随责任。 还包括使用DCL和减充血剂或白三烯抑制剂治疗过敏性哮喘的方法，同时避免与其它非镇静性抗组胺药相关的副作用的伴随的责任。 本发明还包括以鼻腔或口腔喷雾剂施用DCL。

    Methods and compositions using racemic, (R)-, and (S)-fexofenadine in combination with leukotriene inhibitors
    4.
    发明授权
    Methods and compositions using racemic, (R)-, and (S)-fexofenadine in combination with leukotriene inhibitors 有权
    使用外消旋，（R） - 和（S） - 非索非那定与白三烯抑制剂组合的方法和组合物

    公开(公告)号：US08404715B2

    公开(公告)日：2013-03-26

    申请号：US13398669

    申请日：2012-02-16

    Applicant: Paul D. Rubin

    Inventor： Paul D. Rubin

    IPC: A61K31/47 ,  A61K31/445 ,  A61K31/44

    CPC classification number: A61K45/06 ,  A61K31/445 ,  A61K31/47 ,  A61K31/475 ,  A61K31/41 ,  A61K31/405 ,  A61K31/40 ,  A61K2300/00

    Abstract: Methods and pharmaceutical compositions employing a terfenadine metabolite and a leukotriene inhibitor for the treatment or prevention of inflammation or allergic disorders, such as asthma, or symptoms thereof. Also included are methods and compositions employing a terfenadine metabolite, a leukotriene inhibitor, and a decongestant for the treatment or prevention of inflammation or allergic disorders, such as asthma, or symptoms thereof.

    Abstract translation: 使用特非那定代谢物和白三烯抑制剂用于治疗或预防炎症或过敏性疾病如哮喘或其症状的方法和药物组合物。 还包括使用特非那定代谢物，白三烯抑制剂和减充血剂用于治疗或预防炎症或过敏性疾病如哮喘或其症状的方法和组合物。

    Methods for treating irritable bowel syndrome using optically pure (+) norcisapride
    7.
    发明授权
    Methods for treating irritable bowel syndrome using optically pure (+) norcisapride 失效
    使用光学纯（+）诺西沙必丁治疗肠易激综合征的方法

    公开(公告)号：US06369079B1

    公开(公告)日：2002-04-09

    申请号：US09515390

    申请日：2000-02-29

    Applicant: Paul D. Rubin ,  Timothy J. Barberich

    Inventor： Paul D. Rubin ,  Timothy J. Barberich

    IPC: A61K31445

    CPC classification number: A61K31/445 ,  A61K31/4468

    Abstract: Methods for the prevention, treatment, or management of apnea, apnea disorders, bulimia nervosa, irritable bowel syndrome, urinary incontinence, bradycardia, bradyarrhythnia, syncope, other disorders, or symptoms thereof using (+) norcisapride, or a pharmaceutically acceptable salt thereof, substantially free of its (−) stereoisomer.

    Abstract translation: 使用（+）诺西沙必利或其药学上可接受的盐的预防，治疗或治疗呼吸暂停，呼吸暂停障碍，贪食症，肠易激综合征，尿失禁，心动过缓，缓慢性心律失调，晕厥，其他障碍或其症状的方法， 基本上不含（ - ）立体异构体。

    Methods of making and using N-desmethylzopiclone
    8.
    发明授权
    Methods of making and using N-desmethylzopiclone 有权
    制备和使用N-去甲基异佐匹克隆的方法

    公开(公告)号：US06339086B1

    公开(公告)日：2002-01-15

    申请号：US09548607

    申请日：2000-04-13

    Applicant: Thomas P. Jerussi ,  Chrisantha H. Senanayake ,  Paul D. Rubin ,  Fran A. McConville

    Inventor： Thomas P. Jerussi ,  Chrisantha H. Senanayake ,  Paul D. Rubin ,  Fran A. McConville

    IPC: A61K3150

    CPC classification number: A61K31/4985 ,  A61K31/498 ,  C07B2200/07 ,  C07D487/04

    Abstract: The invention is directed to compositions comprising, and methods of using, racemic N-desmethylzopiclone, optically pure (+)-N-desmethylzopiclone, and optically pure (−)-N-desmethylzopiclone in the treatment and prevention of diseases and conditions in mammals. The invention is further directed to novel methods of preparing N-desmethylzopiclone, optically pure (+)-N-desmethylzopiclone, and optically pure (−)-N-desmethylzopiclone.

    Abstract translation: 本发明涉及包含外消旋的N-去甲基佐氮克隆，光学纯的（+） - N-去甲基佐匹克隆和光学纯的（ - ） - N-去甲基佐匹克隆的组合物，其用于治疗和预防哺乳动物的疾病和病症。 本发明进一步涉及制备N-去甲基异佐匹克隆，光学纯的（+） - N-去甲基佐匹克隆和光学纯的（ - ） - N-去甲基异佐匹克隆的新方法。

Patent Agency Ranking