公开(公告)号：US06191931B1

公开(公告)日：2001-02-20

申请号：US09143213

申请日：1998-08-28

申请人： Paul Paspa ,  Craig Mar ,  Joe Beauvais ,  Kenneth Wong

发明人： Paul Paspa ,  Craig Mar ,  Joe Beauvais ,  Kenneth Wong

IPC分类号： H01G435

CPC分类号： H01G9/008 ,  A61N1/3754

摘要： An electrolytic capacitor with an electrically conductive housing defining a chamber and defining a feed-through aperture providing communication between the interior and exterior of the housing. A number of conductive layers are positioned within the chamber. A feed-through conductor has a first end connected to the layers, an intermediate portion passing through the feed-through aperture, and an elongated external portion extending externally from the housing and terminating at a free end. An insulative sleeve has a first portion closely received within the feed-through aperture and closely receiving the intermediate portion of the feed-through member and has a second elongated portion extending externally from the housing and closely receiving at least a portion of the external portion of the conductor element, so that only a remaining portion of the conductor element is exposed, and is spaced apart from the housing by the length of the second elongated portion.

摘要翻译： 一种具有导电壳体的电解电容器，其限定了室并且限定了提供在壳体的内部和外部之间的连通的馈通孔。 多个导电层位于腔室内。 馈通导体具有连接到层的第一端，穿过馈通孔的中间部分和从壳体向外延伸并终止于自由端的细长外部部分。 绝缘套管具有紧密地容纳在馈通孔内的第一部分，并且紧密地容纳穿通构件的中间部分，并且具有从壳体向外延伸的第二细长部分，并且紧密地接收至少一部分外部部分 导体元件，使得只有导体元件的剩余部分露出，并且与壳体间隔第二细长部分的长度。

公开(公告)号：US20100152531A1

公开(公告)日：2010-06-17

申请号：US12634974

申请日：2009-12-10

申请人： Amy M. Goodman ,  Peter M. Martin ,  William Mavity ,  Russell Ivanhoe ,  Matthew G. Fishler ,  Craig Mar

发明人： Amy M. Goodman ,  Peter M. Martin ,  William Mavity ,  Russell Ivanhoe ,  Matthew G. Fishler ,  Craig Mar

IPC分类号： A61M31/00 ,  A61F2/00

CPC分类号： A61F2/2481 ,  A61F2002/2484 ,  A61F2250/0067 ,  A61L31/10 ,  A61L31/16 ,  A61N1/0597 ,  A61N1/3627

摘要： An apparatus and method of preparing a cardiac harness for use in controllably delivering a medicament such as an mTOR inhibitor or aldosterone blockade from the surface of the cardiac harness to the epicardium of a patient's heart for the site-specific treatment of cardiac and non-cardiac maladies. The delivery of the medicament from the cardiac harness is achieved by: coating the medicament on the surface of the cardiac harness; coating the cardiac harness with a polymer material or dielectric material and impregnating the coating with the medicament; or by loading the medicament into an implant attached to the cardiac harness.

摘要翻译： 一种制备心脏线束的装置和方法，用于可控地将诸如mTOR抑制剂或醛固酮阻断剂的药物从心脏线束的表面输送到患者心脏的心外膜用于心脏和非心脏的位点特异性治疗 疟疾 通过以下方式实现药物从心脏线束的输送：在心脏线束的表面上涂覆药物; 用聚合物材料或介电材料涂覆心脏线束并用药物浸渍该涂层; 或通过将药物装载到附接到心脏线束的植入物中。

公开(公告)号：US07282024B2

公开(公告)日：2007-10-16

申请号：US11033409

申请日：2005-01-10

申请人： Lilip Lau ,  Matthew Fishler ,  Craig Mar ,  Steven Meyer ,  Anuja Patel

发明人： Lilip Lau ,  Matthew Fishler ,  Craig Mar ,  Steven Meyer ,  Anuja Patel

IPC分类号： A61F2/00

CPC分类号： A61F2/2481

摘要： A cardiac harness for treating a patient's heart includes elastic rows connected by a connector assembly. The connector assembly can have a specific pattern, or can be formed of elongated elastic material connecting all of the apices of adjacent rows. The connectors maintain proper spacing between rows or rings on the harness and provide longitudinal stability.

摘要翻译： 用于治疗患者心脏的心脏线束包括通过连接器组件连接的弹性排。 连接器组件可以具有特定图案，或者可以由连接相邻行的所有顶点的细长弹性材料形成。 连接器在线束上的行或环之间保持适当的间隔并提供纵向稳定性。

公开(公告)号：US07149588B2

公开(公告)日：2006-12-12

申请号：US10793549

申请日：2004-03-03

申请人： Lilip Lau ,  Matthew G. Fishler ,  Craig Mar

发明人： Lilip Lau ,  Matthew G. Fishler ,  Craig Mar

IPC分类号： A61N1/05

CPC分类号： A61F2/2481 ,  A61F2002/2484 ,  A61N1/0563 ,  A61N1/0587 ,  A61N1/3756

摘要： A system for treating the heart includes a cardiac harness associated with a cardiac rhythm management devise which includes at least electrodes and a power source. The cardiac harness applies a compressive force on the heart during diastole and systole. The electrodes will deliver an electrical shock to the heart for defibrillation and/or can be used for pacing/sensing. The cardiac harness and electrodes are delivered and implanted on the heart by minimally invasive access.

公开(公告)号：US5800336A

公开(公告)日：1998-09-01

申请号：US582301

申请日：1996-01-03

申请人： Geoffrey R. Ball ,  Craig Mar ,  Tim Dietz ,  Bob H. Katz ,  Dan Wallace

发明人： Geoffrey R. Ball ,  Craig Mar ,  Tim Dietz ,  Bob H. Katz ,  Dan Wallace

IPC分类号： H04R25/00

CPC分类号： H04R25/606 ,  H04R25/75

摘要： A floating mass transducer for assisting hearing in a person is provided. Inertial vibration in the floating mass transducer (100) produces vibrations in the inner ear. In an exemplary embodiment, the floating mass transducer comprises a magnet assembly (12) and a coil (14) secured inside a housing (10) which is attached to bone within the middle ear. The coil is more rigidly secured to the housing than the magnet. The magnet assembly and coil are configured such that conducting alternating electrical current through the coil results in vibration of the magnet assembly and coil relative to one another. The vibration is caused by the interaction of the magnetic fields of the magnet assembly and coil. Because the coil is more rigidly secured to the housing than the magnet assembly, the vibrations of the coil cause the housing to vibrate. The floating mass transducer may generate vibrations in the inner ear by being attached to the skull or through a mouthpiece.

摘要翻译： 提供了用于辅助人的听觉的浮动质量传感器。 浮动质量传感器（100）中的惯性振动在内耳产生振动。 在示例性实施例中，浮动质量换能器包括固定在壳体（10）内的磁体组件（12）和线圈（14），所述壳体（10）附接到中耳内的骨骼。 线圈比磁体更牢固地固定到壳体。 磁体组件和线圈被配置成使得通过线圈的交流电流导致磁体组件和线圈相对于彼此的振动。 振动是由磁体组件和线圈的磁场相互作用引起的。 由于线圈比磁体组件更牢固地固定到壳体，所以线圈的振动导致壳体振动。 浮动质量传感器可以通过附接到颅骨或通过口器件在内耳中产生振动。

公开(公告)号：US07976456B2

公开(公告)日：2011-07-12

申请号：US12343253

申请日：2008-12-23

申请人： Lilip Lau ,  James Hong ,  Steven Meyer ,  Matthew G. Fishler ,  Craig Mar ,  Anuja H. Patel ,  Sieu Duong

发明人： Lilip Lau ,  James Hong ,  Steven Meyer ,  Matthew G. Fishler ,  Craig Mar ,  Anuja H. Patel ,  Sieu Duong

IPC分类号： A61F13/00

CPC分类号： A61N1/0587 ,  A61F2/2481 ,  A61N1/368 ,  A61N1/3956 ,  Y10T29/49995

摘要： A cardiac harness for treating or preventing congestive heart failure is configured to be placed about at least a portion of a patient's heart so as to apply a mild compressive force on the heart. In one embodiment, the cardiac harness comprises a plurality of spaced apart conductive panels arranged so that there is no electrical continuity circumferentially around the harness. In an additional embodiment, a cardiac harness is provided that is insulated so as not to conduct electricity circumferentially about the harness.

摘要翻译： 用于治疗或预防充血性心力衰竭的心脏线束被配置为围绕患者心脏的至少一部分放置，以便对心脏施加温和的压力。 在一个实施例中，心脏线束包括多个间隔开的导电面板，其布置成使得在线束周围不具有电连续性。 在另外的实施例中，提供了一种绝缘的心脏线束，以便不围绕线束周向地传导电力。

公开(公告)号：US20070073218A1

公开(公告)日：2007-03-29

申请号：US11235684

申请日：2005-09-26

申请人： Lilip Lau ,  Craig Mar ,  Anh Truong

发明人： Lilip Lau ,  Craig Mar ,  Anh Truong

IPC分类号： A61M31/00

CPC分类号： A61F2/2481 ,  A61B17/00491 ,  A61B2017/00243 ,  A61B2017/00557 ,  A61F2250/0003

摘要： An inflatable cardiac device for placement in the pericardial sac is described. The inflatable cardiac device is useful for treatment of congestive heart failure and for attenuating or reversing remodeling of the heart. In some embodiments, the device further includes filling catheters connected with reservoirs, on-off devices, or pressure transducers. The device may also include a drug delivery system. At least one embodiment includes electrodes capable of connection with an implantable electronic medical device such as a pacemaker or defibrillator.

摘要翻译： 描述了用于放置在心包囊中的可充气心脏装置。 充气心脏装置可用于治疗充血性心力衰竭和减轻或逆转心脏重建。 在一些实施例中，该装置还包括填充与储存器，开关装置或压力换能器连接的导管。 该装置还可以包括药物递送系统。 至少一个实施例包括能够与诸如起搏器或除颤器之类的可植入电子医疗装置连接的电极。

公开(公告)号：US20050054892A1

公开(公告)日：2005-03-10

申请号：US10888806

申请日：2004-07-08

申请人： Lilip Lau ,  James Hong ,  Matthew Fishler ,  Craig Mar ,  Steven Meyer

发明人： Lilip Lau ,  James Hong ,  Matthew Fishler ,  Craig Mar ,  Steven Meyer

IPC分类号： A61B19/00 ,  A61F2/00 ,  A61F2/04

CPC分类号： A61F2/2481

摘要： A self-anchoring cardiac harness is configured to fit at least a portion of a patient's heart and includes a tissue engaging element for frictionally engaging an outer surface of a heart. The engaging element produces sufficient friction relative to the outer surface of the heart, so that the harness does not migrate substantially relative to the heart. There is enough force created by the engaging element that there is no need to apply a suture to the heart in order to retain the cardiac harness. Further, the engaging element is adapted to engage the outer surface of the heart without substantially penetrating the outer surface.

摘要翻译： 自锚式心脏线束被配置为装配患者心脏的至少一部分，并且包括用于摩擦接合心脏外表面的组织接合元件。 接合元件相对于心脏的外表面产生足够的摩擦力，使得线束不会相对于心脏基本上迁移。 通过啮合元件产生足够的力，不需要将缝合线应用于心脏以便保持心脏线束。 此外，接合元件适于接合心脏的外表面而基本上不穿透外表面。

公开(公告)号：US07485089B2

公开(公告)日：2009-02-03

申请号：US10656722

申请日：2003-09-05

申请人： Lilip Lau ,  James Hong ,  Steven Meyer ,  Matthew G. Fishler ,  Craig Mar ,  Anuja H. Patel ,  Sieu Dong

发明人： Lilip Lau ,  James Hong ,  Steven Meyer ,  Matthew G. Fishler ,  Craig Mar ,  Anuja H. Patel ,  Sieu Dong

IPC分类号： A61F13/00

CPC分类号： A61N1/0587 ,  A61F2/2481 ,  A61N1/368 ,  A61N1/3956 ,  Y10T29/49995

摘要： A cardiac harness for treating or preventing congestive heart failure is configured to be placed about at least a portion of a patient's heart so as to apply a mild compressive force on the heart. In one embodiment, the cardiac harness comprises a plurality of spaced apart conductive panels arranged so that there is no electrical continuity circumferentially around the harness. In an additional embodiment, a cardiac harness is provided that is insulated so as not to conduct electricity circumferentially about the harness.

摘要翻译： 用于治疗或预防充血性心力衰竭的心脏线束被配置为围绕患者心脏的至少一部分放置，以便对心脏施加温和的压力。 在一个实施例中，心脏线束包括多个间隔开的导电面板，其布置成使得在线束周围不具有电连续性。 在另外的实施例中，提供了一种绝缘的心脏线束，以便不围绕线束周向地传导电力。

公开(公告)号：US20070293718A1

公开(公告)日：2007-12-20

申请号：US11843010

申请日：2007-08-22

申请人： Lilip Lau ,  James Hong ,  Matthew Fishler ,  Craig Mar ,  Steven Meyer

发明人： Lilip Lau ,  James Hong ,  Matthew Fishler ,  Craig Mar ,  Steven Meyer

IPC分类号： A61F13/00

CPC分类号： A61F2/2481 ,  A61B17/205 ,  A61B2017/00247 ,  A61B2018/00392 ,  A61N1/0587 ,  A61N1/3956

摘要： A self-anchoring cardiac harness is configured to fit at least a portion of a patient's heart and includes a tissue engaging element for frictionally engaging an outer surface of a heart. The engaging element produces sufficient friction relative to the outer surface of the heart, so that the harness does not migrate substantially relative to the heart. There is enough force created by the engaging element that there is no need to apply a suture to the heart in order to retain the cardiac harness. Further, the engaging element is adapted to engage the outer surface of the heart without substantially penetrating the outer surface.

摘要翻译： 自锚式心脏线束被配置为装配患者心脏的至少一部分，并且包括用于摩擦接合心脏外表面的组织接合元件。 接合元件相对于心脏的外表面产生足够的摩擦力，使得线束不会相对于心脏基本上迁移。 通过啮合元件产生足够的力，不需要将缝合线应用于心脏以便保持心脏线束。 此外，接合元件适于接合心脏的外表面而基本上不穿透外表面。