公开(公告)号：US09457184B2

公开(公告)日：2016-10-04

申请号：US11910915

申请日：2006-04-06

申请人： Friederike Scharmer

发明人： Friederike Scharmer

IPC分类号： A61N1/365 ,  A61N1/32 ,  A61N1/362 ,  A61N1/368 ,  A61N1/378 ,  A61N1/05 ,  A61N1/372 ,  A61N1/36

CPC分类号： A61N1/32 ,  A61N1/0597 ,  A61N1/36014 ,  A61N1/3605 ,  A61N1/3625 ,  A61N1/368 ,  A61N1/37252 ,  A61N1/3787

摘要： An electromedical implantable or externally applicable device allows healing processes to be excited in diseased organs. The device comprises a programmable generator and receiver unit (3) which generates and receives electrical microcurrents and electromagnetic power and is connected in a conducting manner to electrodes (4, 5), a telemetry unit (6) that is integrated into the generator and receiver unit (3) and is provided with a transmitter and a receiver for exchanging data with extracorporeal devices, and a power supply unit (7).

摘要翻译： 电动植入式或外部装置允许愈合过程在患病器官中被激发。 该装置包括可编程发生器和接收器单元（3），其生成和接收电微电流和电磁功率，并以导电方式连接到电极（4,5），遥测单元（6），其集成到发电机和接收器 单元（3），并且设置有用于与体外设备交换数据的发射器和接收器，以及电源单元（7）。

公开(公告)号：US08942828B1

公开(公告)日：2015-01-27

申请号：US13447064

申请日：2012-04-13

申请人： Stuart O. Schecter

发明人： Stuart O. Schecter

IPC分类号： A61N1/00 ,  A61N1/05

CPC分类号： A61N1/05 ,  A61B2017/00199 ,  A61B2017/00243 ,  A61B2017/00539 ,  A61B2017/00544 ,  A61B2017/00867 ,  A61B2017/00946 ,  A61B2017/0237 ,  A61B2018/00297 ,  A61B2018/00577 ,  A61B2018/00595 ,  A61B2034/302 ,  A61B2090/064 ,  A61B2090/065 ,  A61B2090/066 ,  A61B2217/005 ,  A61B2217/007 ,  A61H31/004 ,  A61H31/005 ,  A61H31/006 ,  A61H31/007 ,  A61H2201/10 ,  A61H2201/105 ,  A61H2201/1253 ,  A61H2201/1678 ,  A61H2201/5023 ,  A61H2201/5061 ,  A61H2201/5092 ,  A61H2230/04 ,  A61H2230/207 ,  A61N1/056 ,  A61N1/0595 ,  A61N1/0597

摘要： A family of minimally-invasive surgical (MIS) cardiac interventional tools with tactile feedback based upon cardiac mechanical data and physiologic parameters derived from sensors positioned upon the tools are configurable for optimal placement of an end-effector to provide acute cardiac resuscitation and/or remote cardiovascular intervention for a subject. A haptic interface (e.g., a haptic handle, haptic glove or a simulated haptic heart) provides a clinician with real, not virtual, interaction with the cardiovascular anatomy (including intrathoracic organs) of the subject to optimize end-effector placement. The MIS tools optionally include webbed blade portions for exploration of extracardiac or intrathoracic spaces. The blade portions are initially collapsed but expand into an array of finger-like projections that function as sensors, dilatation and/or dissection tools, pharmacological delivery tools, and/or electrodes for sensing, pacing and defibrillation, and/or as a manual, semi-automatic or fully automatic mechanical support system for cardiac resuscitation and/or for restoring intrathoracic organ function(s).

摘要翻译： 一系列微创手术（MIS）心脏介入手段，具有基于心脏机械数据的触觉反馈和从位于工具上的传感器产生的生理参数，可配置用于最终放置末端执行器以提供急性心脏复苏和/或远程 心血管介入治疗。 触觉界面（例如，触觉手柄，触觉手套或模拟的触觉心脏）向临床医生提供与受试者的心血管解剖（包括胸内器官）的实际而非虚拟的相互作用以优化末端执行器放置。 MIS工具可选地包括用于探查心外或胸腔内空间的腹板部分。 叶片部分最初被折叠，但是扩展成用作感测，起搏和除颤的传感器，扩张和/或解剖工具，药理学递送工具和/或电极的手指状突起的阵列，和/或作为手动， 半自动或全自动机械支持系统，用于心脏复苏和/或恢复胸腔内器官功能。

公开(公告)号：US20130226272A1

公开(公告)日：2013-08-29

申请号：US13818663

申请日：2011-08-26

申请人： Giorgio Cattaneo ,  Alfred Stett ,  A. Gharabaghi

发明人： Giorgio Cattaneo ,  Alfred Stett ,  A. Gharabaghi

IPC分类号： A61N1/36

CPC分类号： A61N1/36114 ,  A61N1/0551 ,  A61N1/056 ,  A61N1/0597

摘要： An electrode for medical applications for neuromodulation and/or nerve stimulation and/or neurological signal detection, which electrode can be compressed and expanded in order to insert same into a hollow organ of a body and is or can be coupled to a current supply. The electrode has a compressible and expandable lattice structure including lattice webs, which form cells, wherein the lattice structure is or can be coupled to the current supply and forms at least one electrically conductive region and at least one electrically insulated region.

摘要翻译： 用于神经调节和/或神经刺激和/或神经信号检测的医疗应用的电极，该电极可以被压缩和扩张，以将其插入身体的中空器官并且可以耦合到电流源。 电极具有可压缩和可扩展的格子结构，其包括晶格网，其形成电池，其中晶格结构可耦合到电流源并形成至少一个导电区域和至少一个电绝缘区域。

公开(公告)号：US20130079861A1

公开(公告)日：2013-03-28

申请号：US13626381

申请日：2012-09-25

申请人： Medtronics, Inc.

发明人： Michael A. Reinert ,  Eric R. Williams ,  Todd J. Sheldon

IPC分类号： A61N1/05

CPC分类号： A61B5/0538 ,  A61B5/0031 ,  A61B5/0422 ,  A61B5/0424 ,  A61B5/11 ,  A61B5/686 ,  A61B5/6869 ,  A61B5/6882 ,  A61B5/6883 ,  A61B2560/0276 ,  A61B2560/0468 ,  A61N1/0597 ,  A61N1/36542 ,  A61N1/371 ,  A61N1/3756 ,  A61N2001/083

摘要： Techniques for determining an attachment stability of leadless pacing device (LPD) implanted within a patient are described. For example, the LPD may detect one or more stability metrics from one or more electrodes of the LPD and/or an activity sensor within the LPD. Based on one or more of these stability metrics, e.g., a mechanical motion of the LPD, a stability module within the LPD may determine the attachment stability of the LPD within the patient. If the attachment stability is insufficient to provide efficacious therapy or indicates at least partial dislodgement of the LPD from tissue, the LPD may wirelessly transmit stability information to an external device. In some examples, the LPD may be implanted within a chamber of the heart.

摘要翻译： 描述了用于确定植入在患者体内的无引脚起搏装置（LPD）的附着稳定性的技术。 例如，LPD可以从LPD的一个或多个电极和/或LPD内的活动传感器检测一个或多个稳定性度量。 基于这些稳定性度量中的一个或多个，例如LPD的机械运动，LPD内的稳定性模块可以确定患者体内LPD的附着稳定性。 如果连接稳定性不足以提供有效的治疗或指示LPD至少部分从组织移走，则LPD可以将稳定性信息无线传输到外部设备。 在一些实例中，LPD可以植入心脏的腔室内。

公开(公告)号：US20070197859A1

公开(公告)日：2007-08-23

申请号：US11430638

申请日：2006-05-09

申请人： Alan Schaer ,  Matthew Fishler

发明人： Alan Schaer ,  Matthew Fishler

IPC分类号： A61F2/00

CPC分类号： A61N1/0587 ,  A61F2/2481 ,  A61F2002/2484 ,  A61N1/0597

摘要： A cardiac harness adapted to fit generally around a least a portion of a heart includes at least one elastic spring member forming an annular portion that is elastically deformable and at least one sensor disposed on the annular portion for providing a sensor signal representative of cardiac function. The cardiac harness applies a compressive force on the heart during diastole and systole. The sensor is configured to take a measurement of impedance across the heart, impedance across a lung, evoked response of the heart, activation patterns of the heart, acceleration of a portion of the heart, position of a portion of the heart relative to an ultrasonic transmitter, pH on the heart's epicardial surface, blood oxygen saturation of a portion of the heart, or position of a portion of the heart relative to a magnetic field generating device. The cardiac harness and sensor are delivered and implanted on the heart by minimally invasive access.

摘要翻译： 适于大致围绕心脏的至少一部分配合的心脏线束包括形成可弹性变形的环形部分的至少一个弹性弹簧构件和设置在环形部分上的至少一个传感器，用于提供表示心脏功能的传感器信号。 心脏线束在舒张期和收缩期间对心脏施加压缩力。 传感器被配置为对心脏上的阻抗进行测量，穿过肺的阻抗，心脏的诱发反应，心脏的激活模式，心脏的一部分的加速度，心脏的一部分相对于超声波的位置 发射器，心脏心脏表面上的pH，心脏的一部分的血氧饱和度或心脏部分相对于磁场产生装置的位置。 通过微创入路将心脏线束和传感器输送和植入心脏。

公开(公告)号：US20050288715A1

公开(公告)日：2005-12-29

申请号：US11158913

申请日：2005-06-21

申请人： Lilip Lau ,  Matthew Fishler ,  Craig Mar

发明人： Lilip Lau ,  Matthew Fishler ,  Craig Mar

IPC分类号： A61N1/05 ,  A61N1/375 ,  A61N1/39

CPC分类号： A61N1/0587 ,  A61F2/2481 ,  A61F2002/2484 ,  A61N1/0597 ,  A61N1/3627 ,  A61N1/3756 ,  A61N1/3962

摘要： A system for treating the heart includes a cardiac harness associated with a cardiac rhythm management device which includes at least one set of electrodes and a power source. At least one electrode from the at least one set of electrodes is selected for sensing heart functions and providing pacing stimuli. The remaining electrodes not selected to provide pacing and sensing functions to the heart can be arranged together to deliver a defibrillating shock. The cardiac harness and electrodes are delivered and implanted on the heart by minimally invasive access.

摘要翻译： 用于治疗心脏的系统包括与包括至少一组电极和电源的心律管理装置相关联的心脏线束。 选择来自至少一组电极的至少一个电极用于感测心脏功能并提供起搏刺激。 未被选择为向心脏提供起搏和感测功能的剩余电极可以被布置在一起以产生去颤颤动。 通过微创入路将心脏线束和电极输送并植入心脏。

公开(公告)号：US09566443B2

公开(公告)日：2017-02-14

申请号：US14090383

申请日：2013-11-26

申请人： CorQuest Medical, Inc.

发明人： Didier de Canniere

IPC分类号： A61F2/24 ,  A61N1/368 ,  A61M1/10 ,  A61N1/05

CPC分类号： A61N1/368 ,  A61M1/1008 ,  A61M1/106 ,  A61M1/1068 ,  A61M1/12 ,  A61M1/127 ,  A61N1/0587 ,  A61N1/0597 ,  A61N1/3684

摘要： A system for treating heart valve malfunction specifically including mitral regurgitation including a positioning structure operative to assume both expanded and contracted orientations and a retaining assembly positioned and structured to operatively dispose the positioning structure in moveably supporting lifting and/or positioning relation to the ventricular wall portion of the heart. The retaining assembly and the positioning structure are cooperatively disposed and structured to accomplish a shape variance of the heart upon a lifting or positioning force being exerted thereon substantially concurrent to the positioning structure being disposed in the expanded orientation. The force exerted on the heart at least partially defines a shape variance thereof to the extent of positioning of the leaflets of the mitral valve into a closed orientation which restricts mitral regurgitation.

摘要翻译： 一种用于治疗心脏瓣膜功能障碍的系统，其特征在于包括二尖瓣反流，其包括可操作地承担伸展和收缩取向的定位结构，以及定位和构造成将定位结构可操作地设置成可移动地支撑提升和/或定位关系到心室壁部分的保持组件 的心脏 保持组件和定位结构协同地设置和构造成在施加在提升或定位力上时实现心脏的形状变化，其基本上与定位结构基本上同时地设置在展开方向上。 施加在心脏上的力至少部分地将其形状方差定义为将二尖瓣的传单定位成限制二尖瓣反流的闭合取向的程度。

公开(公告)号：US20160317729A1

公开(公告)日：2016-11-03

申请号：US15140058

申请日：2016-04-27

申请人： THE TEXAS A&M UNIVERSITY SYSTEM ,  CorInnova Incorporated

发明人： John C. Criscione ,  Boris Leschinsky

IPC分类号： A61M1/10 ,  A61F2/24 ,  A61B5/00 ,  A61N1/39 ,  A61M1/12 ,  A61N1/05

CPC分类号： A61M1/1068 ,  A61B5/686 ,  A61B5/6869 ,  A61B5/6876 ,  A61F2250/0067 ,  A61M1/106 ,  A61M1/1067 ,  A61M1/107 ,  A61M1/12 ,  A61M1/122 ,  A61M2205/054 ,  A61N1/0597 ,  A61N1/3962

摘要： The present invention provides a combined direct cardiac compression and aortic counterpulsation device comprising: an inflatable direct cardiac compression jacket configured when inflated to directly compress a heart and assist in displacing blood therefrom, an aortic counterpulsation chamber configured when inflated to displace aortic volume for the purposes of causing a counterpulsation effect, and a driver operably connected to said inflatable direct cardiac compression jacket and to said aortic counterpulsation chamber, said driver is configured to inflate said direct cardiac compression jacket and to deflate said aortic counterpulsation chamber during systole of the heart; said driver is further configured to deflate said direct cardiac compression jacket and to inflate said aortic counterpulsation chamber during diastole of the heart.

摘要翻译： 本发明提供组合的直接心脏压缩和主动脉反搏装置，其包括：充气的直接心脏压缩套管，其被配置为当膨胀以直接压缩心脏并且有助于从其中移位血液时被配置;主动脉反搏室，当被膨胀以置换主动脉体积用于该目的时 引起反搏效应的驱动器，以及可操作地连接到所述可膨胀的直接心脏压缩套管和所述主动脉反应室的驱动器，所述驱动器构造成使所述直接心脏压缩套管膨胀并且在心脏收缩期间使所述主动脉反搏室收缩; 所述驾驶员进一步构造为在所述心脏舒张期间使所述直接心脏压缩套管收缩并使所述主动脉反搏室膨胀。

公开(公告)号：US09463316B2

公开(公告)日：2016-10-11

申请号：US14465253

申请日：2014-08-21

申请人： Peter Osypka

发明人： Peter Osypka

IPC分类号： A61N1/05 ,  A61N1/39 ,  A61N1/04 ,  A61N1/368

CPC分类号： A61N1/059 ,  A61N1/0492 ,  A61N1/0597 ,  A61N1/3684 ,  A61N1/3968

摘要： An electrode assembly for temporary cardioversion/defibrillation and/or for temporary stimulation of the heart after open heart surgery consisting of two defibrillation electrodes with at least one indifferent pole each and an elastic section is disclosed. Each defibrillation electrode in the operating position is positioned on the right and left atrium. The defibrillation electrodes each distally comprise a fixation member and each end in a protective tube to protect the epicardium at a proximal end. The fixation members are elastic and enable reversible fastening of the defibrillation electrodes in the pericardium on the right and left side. The protective tubes are preferably fed together into a guide tube, where the guide tube is slidable along the longitudinal axis. The stimulation electrodes (different electrode poles) for stimulation of the atria are designed appropriately together with the defibrillation electrode in one piece.

摘要翻译： 公开了一种用于临时心脏复律/除颤和/或用于心脏手术后暂时刺激心脏手术的电极组件，该电极组件由具有至少一个无差异极点的两个除颤电极和弹性部分组成。 操作位置的每个除颤电极位于右心房和左心房。 除颤电极各自远端包括固定构件，并且每个端部保护管中以在近端保护心外膜。 固定构件是弹性的，并且能够使右心和左侧的除颤电极可逆地紧固在心包中。 保护管优选地一起馈送到引导管中，其中引导管可沿着纵向轴线滑动。 用于刺激心房的刺激电极（不同电极极）与除颤电极一起适当地设计。

公开(公告)号：US09283383B2

公开(公告)日：2016-03-15

申请号：US14241091

申请日：2012-08-16

申请人： Peter Osypka

发明人： Peter Osypka

IPC分类号： A61N1/05 ,  A61N1/39 ,  A61N1/362

CPC分类号： A61N1/059 ,  A61N1/0597 ,  A61N1/3625 ,  A61N1/3918 ,  A61N1/3956

摘要： An implantable epicardial electrode assembly comprises electrode poles fixed on the heart having a large surface area and being multipolar and can at the same time be used as sensing and stimulating electrodes, wherein the electrode assembly has the shape of a tennis racket or is circular, elliptical, hexagonal, rectangular, oakleaf-shaped, star-shaped or cloverleaf-shaped and comprises at least two electrode poles which are arranged over a large surface area, and a further electrode arrangement which comprises at least one electrode pole and which is arranged between the large surface area electrode poles and further comprises a fixing element, wherein the defibrillation can take place between the mutually insulated poles of the electrodes, and wherein the stimulation of the heart can take place between one of the electrode poles and a pole of the electrode arrangement.

摘要翻译： 可植入的心外膜电极组件包括固定在心脏上的具有大表面积并且是多极的电极，并且可以同时用作感测和刺激电极，其中电极组件具有网球拍的形状或是圆形，椭圆形 六角形，矩形，橡木形，星形或苜蓿叶形，并且包括布置在大表面积上的至少两个电极极，以及另外的电极装置，其包括至少一个电极，并且布置在 大表面电极极还包括固定元件，其中除颤可以在电极的相互绝缘的极之间发生，并且其中心脏的刺激可以发生在电极极之一和电极装置的极之间 。