公开(公告)号：US20090285722A1

公开(公告)日：2009-11-19

申请号：US12383058

申请日：2009-03-19

申请人： Paul R. Soskey ,  Jerome F. Parmer, JR. ,  Harris A. Goldberg ,  Douglas P. Karim ,  Laxmi Samantara ,  Carrie A. Feeney ,  Michele Farrell

发明人： Paul R. Soskey ,  Jerome F. Parmer, JR. ,  Harris A. Goldberg ,  Douglas P. Karim ,  Laxmi Samantara ,  Carrie A. Feeney ,  Michele Farrell

IPC分类号： B01L3/00 ,  B05D3/00 ,  B05D3/06

CPC分类号： B01L3/50825 ,  A61B5/15003 ,  A61B5/150274 ,  A61B5/150351 ,  A61B5/150755 ,  A61B5/154 ,  B01L2200/12 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/12 ,  B01L2300/16 ,  B01L2300/161 ,  B01L2300/168

摘要： An evacuated container assembly suitable for use in connection with blood collection including: (a) a container member formed of a first polymeric material and having a sidewall and one or more openings; (b) a nanocomposite barrier coating disposed on the container member having a thickness of up to about 30 microns and being derived from an aqueous dispersion including (i) a dispersed barrier matrix polymer; and (ii) a substantially exfoliated silicate filler having an aspect ratio of more than 50; and (c) one or more sealing members disposed in the opening(s) operative to hermetically seal the cavity; wherein the cavity is evacuated and maintains a pressure below atmospheric pressure and exhibits a draw volume loss lower than that of a like assembly without a nanocomposite barrier film by a factor of at least 1.5.

摘要翻译： 适于与血液收集相关联的真空容器组件，包括：（a）由第一聚合物材料形成并具有侧壁和一个或多个开口的容器构件; （b）设置在所述容器构件上的厚度高达约30微米的纳米复合屏障涂层，其衍生自包含（i）分散的阻隔基质聚合物的水分散体; 和（ii）长宽比大于50的基本上剥离的硅酸盐填料; 和（c）设置在所述开口中的一个或多个密封构件，用于气密地密封所述空腔; 其中所述空腔被抽真空并保持低于大气压力的压力，并且显示比不具有至少1.5倍的纳米复合阻挡膜的类似组件的拉伸体积损失。

公开(公告)号：US09782776B2

公开(公告)日：2017-10-10

申请号：US12383058

申请日：2009-03-19

申请人： Paul R. Soskey ,  Jerome F. Parmer, Jr. ,  Harris A. Goldberg ,  Douglas P. Karim ,  Laxmi Samantara ,  Carrie A. Feeney ,  Michele Farrell

发明人： Paul R. Soskey ,  Jerome F. Parmer, Jr. ,  Harris A. Goldberg ,  Douglas P. Karim ,  Laxmi Samantara ,  Carrie A. Feeney ,  Michele Farrell

IPC分类号： B01L3/14 ,  B01L3/00 ,  A61B5/15 ,  A61B5/154

CPC分类号： B01L3/50825 ,  A61B5/15003 ,  A61B5/150274 ,  A61B5/150351 ,  A61B5/150755 ,  A61B5/154 ,  B01L2200/12 ,  B01L2200/141 ,  B01L2200/16 ,  B01L2300/044 ,  B01L2300/12 ,  B01L2300/16 ,  B01L2300/161 ,  B01L2300/168

摘要： An evacuated container assembly suitable for use in connection with blood collection including: (a) a container member formed of a first polymeric material and having a sidewall and one or more openings; (b) a nanocomposite barrier coating disposed on the container member having a thickness of up to about 30 microns and being derived from an aqueous dispersion including (i) a dispersed barrier matrix polymer; and (ii) a substantially exfoliated silicate filler having an aspect ratio of more than 50; and (c) one or more sealing members disposed in the opening(s) operative to hermetically seal the cavity; wherein the cavity is evacuated and maintains a pressure below atmospheric pressure and exhibits a draw volume loss lower than that of a like assembly without a nanocomposite barrier film by a factor of at least 1.5.

公开(公告)号：US08367193B1

公开(公告)日：2013-02-05

申请号：US12383073

申请日：2009-03-19

申请人： Douglas P. Karim ,  Laxmi Samantara ,  Carrie A. Feeney ,  Michele Farrell ,  Harris A. Goldberg

发明人： Douglas P. Karim ,  Laxmi Samantara ,  Carrie A. Feeney ,  Michele Farrell ,  Harris A. Goldberg

IPC分类号： C08K3/34

CPC分类号： C08K3/34 ,  C08K3/013 ,  C08K5/0041 ,  C08K5/3417 ,  C08K9/04 ,  C09D5/028 ,  C09D7/68

摘要： The invention relates in one aspect to a post-formulation concentrated nanocomposite dispersion containing an invisible marker dye. The dispersion typically includes a silicate filler and a matrix polymer dispersed in an aqueous medium as well. The dispersions form optically transparent barrier films wherein the dye is effective to indicate film thickness on a substrate. Specific embodiments of this invention include a nanocomposite coating formulation designed to provide transparent high barrier coatings at thicknesses from 1 to 10 microns that include a near infrared (NIR) or infrared (IR) dye that enables rapid measurement of coating thickness and uniformity. The preferred dye imparts no observable color or appearance change, and thus can also function as an identifier for the coating.

摘要翻译： 本发明在一个方面涉及含有不可见标记染料的后制剂浓缩纳米复合物分散体。 分散体通常包括分散在水性介质中的硅酸盐填料和基质聚合物。 分散体形成光学透明的阻挡膜，其中染料有效地指示基底上的膜厚度。 本发明的具体实施方案包括设计用于提供厚度为1至10微米的透明高阻隔涂层的纳米复合涂层制剂，其包括能够快速测量涂层厚度和均匀性的近红外（NIR）或红外（IR）染料。 优选的染料不产生可观察到的颜色或外观变化，因此也可以用作涂层的标识。