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公开(公告)号:US07495014B2
公开(公告)日:2009-02-24
申请号:US10767638
申请日:2004-01-29
申请人: Paul S. Charifson , David D. Deininger , Anne-Laure Grillot , Yusheng Liao , Steven M. Ronkin , Dean Stamos , Emanuele Perola , Tiensheng Wang , Arnaud LeTiran , Joseph Drumm
发明人: Paul S. Charifson , David D. Deininger , Anne-Laure Grillot , Yusheng Liao , Steven M. Ronkin , Dean Stamos , Emanuele Perola , Tiensheng Wang , Arnaud LeTiran , Joseph Drumm
IPC分类号: A61K31/44 , C07D401/04 , C07D401/14
CPC分类号: C07D401/14 , C07D403/04 , C07D403/14 , C07D405/04 , C07D405/14 , C07D413/14 , C07D417/14 , C07D471/04 , C07D487/04 , C07D491/04
摘要: The present invention relates to compounds which inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.
摘要翻译: 本发明涉及抑制细菌促旋酶和/或Topo IV的化合物和包含所述化合物的药学上可接受的组合物。 这些化合物及其组合物可用于治疗细菌感染。 因此,本发明还涉及用于治疗哺乳动物细菌感染的方法。