-
公开(公告)号：US08501699B2
公开(公告)日：2013-08-06
申请号：US13607472
申请日：2012-09-07
申请人： Paula Francom , Barbara Frey , Silas Bond , Alistair George Draffan , Michael Harding , Richard Hufton , Saba Hangiri , Michael John Lilly , Edward Tyndall , Jianmin Duan , Richard Bethell , George Kukolj
发明人： Paula Francom , Barbara Frey , Silas Bond , Alistair George Draffan , Michael Harding , Richard Hufton , Saba Hangiri , Michael John Lilly , Edward Tyndall , Jianmin Duan , Richard Bethell , George Kukolj
CPC分类号： C07H19/04
摘要： The present disclosure relates to the use and methods of manufacture of bicyclic nucleosides and nucleotides for the treatment and prevention of infectious and proliferative diseases, including microbial infections and cancer.
摘要翻译： 本公开涉及用于治疗和预防感染性和增殖性疾病（包括微生物感染和癌症）的双环核苷和核苷酸的制备方法和制备方法。
-
公开(公告)号：US20100035836A1
公开(公告)日：2010-02-11
申请号：US12496311
申请日：2009-07-01
申请人： Paula Francom , Barbara Frey , Silas Bond , Alistair George Draffan , Michael Harding , Richard Hufton , Saba Jahangiri , Michael John Lilly , Edward Tyndall , Jianmin Duan , Richard Bethell , George Kukolj
发明人： Paula Francom , Barbara Frey , Silas Bond , Alistair George Draffan , Michael Harding , Richard Hufton , Saba Jahangiri , Michael John Lilly , Edward Tyndall , Jianmin Duan , Richard Bethell , George Kukolj
CPC分类号： C07H19/04
摘要： The present disclosure relates to the use and methods of manufacture of bicyclic nucleosides and nucleotides for the treatment and prevention of infectious and proliferative diseases, including microbial infections and cancer.
摘要翻译： 本公开涉及用于治疗和预防感染性和增殖性疾病（包括微生物感染和癌症）的双环核苷和核苷酸的制备方法和制备方法。
-
公开(公告)号：US20130018013A1
公开(公告)日：2013-01-17
申请号：US13607472
申请日：2012-09-07
申请人： Paula Francom , Barbara Frey , Silas Bond , Alistair George Draffan , Michael Harding , Richard Hufton , Saba Jahangiri , Michael John Lilly , Edward Tyndall , Jianmin Duan , Richard Bethell , George Kukolj
发明人： Paula Francom , Barbara Frey , Silas Bond , Alistair George Draffan , Michael Harding , Richard Hufton , Saba Jahangiri , Michael John Lilly , Edward Tyndall , Jianmin Duan , Richard Bethell , George Kukolj
IPC分类号： A61K31/706 , A61P31/14 , C07H19/23
CPC分类号： C07H19/04
摘要： The present disclosure relates to the use and methods of manufacture of bicyclic nucleosides and nucleotides for the treatment and prevention of infectious and proliferative diseases, including microbial infections and cancer.
摘要翻译： 本公开涉及用于治疗和预防感染性和增殖性疾病（包括微生物感染和癌症）的双环核苷和核苷酸的制备方法和制备方法。
-
公开(公告)号：US08119607B2
公开(公告)日：2012-02-21
申请号：US12496311
申请日：2009-07-01
申请人： Paula Francom , Barbara Frey , Silas Bond , Alistair George Draffan , Michael Harding , Richard Hufton , Saba Jahangiri , Michael John Lilly , Edward Tyndall , Jianmin Duan , Richard Bethell , George Kukolj
发明人： Paula Francom , Barbara Frey , Silas Bond , Alistair George Draffan , Michael Harding , Richard Hufton , Saba Jahangiri , Michael John Lilly , Edward Tyndall , Jianmin Duan , Richard Bethell , George Kukolj
CPC分类号： C07H19/04
摘要： The present disclosure relates to the use and methods of manufacture of bicyclic nucleosides and nucleotides for the treatment and prevention of infectious and proliferative diseases, including microbial infections and cancer.
摘要翻译： 本公开涉及用于治疗和预防感染性和增殖性疾病（包括微生物感染和癌症）的双环核苷和核苷酸的制备方法和制备方法。
-
公开(公告)号：US20120122811A1
公开(公告)日：2012-05-17
申请号：US13348429
申请日：2012-01-11
申请人： Paula Francom , Barbara Frey , Silas Bond , Jianmin Duan , Richard Bethell , George Kukolj
发明人： Paula Francom , Barbara Frey , Silas Bond , Jianmin Duan , Richard Bethell , George Kukolj
IPC分类号： A61K31/706 , C12N5/071 , A61P31/16 , C07H19/23
CPC分类号： C07H19/04
摘要： The present disclosure relates to the use and methods of manufacture of bicyclic nucleosides and nucleotides for the treatment and prevention of infectious and proliferative diseases, including microbial infections and cancer.
摘要翻译： 本公开涉及用于治疗和预防感染性和增殖性疾病（包括微生物感染和癌症）的双环核苷和核苷酸的制备方法和制备方法。
-
公开(公告)号：US08415309B2
公开(公告)日：2013-04-09
申请号：US13348429
申请日：2012-01-11
申请人： Paula Francom , Barbara Frey , Jianmin Duan , Richard Bethell , George Kukolj
发明人： Paula Francom , Barbara Frey , Jianmin Duan , Richard Bethell , George Kukolj
CPC分类号： C07H19/04
摘要： The present disclosure relates to the use and methods of manufacture of bicyclic nucleosides and nucleotides for the treatment and prevention of infectious and proliferative diseases, including microbial infections and cancer.
-
公开(公告)号：US20120142686A1
公开(公告)日：2012-06-07
申请号：US13278021
申请日：2011-10-20
申请人： Rosliana Halim , Michael Harding , Richard Hufton , Craig James Morton , Saba Jahangiri , Brett Raymond Pool , Tyrone Pieter Jeynes , Alistair George Draffan , Barbara Frey , Michael John Lilly
发明人： Rosliana Halim , Michael Harding , Richard Hufton , Craig James Morton , Saba Jahangiri , Brett Raymond Pool , Tyrone Pieter Jeynes , Alistair George Draffan , Barbara Frey , Michael John Lilly
IPC分类号： A61K31/416 , C07D403/12 , C07D401/12 , C07D413/12 , C07D405/12 , C07D417/02 , C07D413/14 , A61K31/454 , A61K31/5377 , A61K31/497 , A61K31/427 , A61K31/4178 , A61P31/14 , C12N9/99 , C12N5/02 , C07D231/56
CPC分类号： C07D231/56 , C07D401/04 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/04
摘要： The present invention relates to viral polymerase inhibitors of formula (I), salts, N-oxides, solvates, hydrates, racemates, enantiomers or isomers thereof, processes for their preparation and their use in the treatment of Flaviviridae viral infections such as Hepatitis C virus (HCV) infections:
摘要翻译： 本发明涉及式（I）的病毒聚合酶抑制剂，其盐，N-氧化物，溶剂合物，水合物，外消旋物，对映体或异构体，其制备方法及其在治疗黄病毒病毒感染如丙型肝炎病毒 （HCV）感染：
-
公开(公告)号：US08546389B2
公开(公告)日：2013-10-01
申请号：US13278021
申请日：2011-10-20
申请人： Rosliana Halim , Michael Harding , Richard Hufton , Craig James Morton , Saba Jahangiri , Brett Raymond Pool , Tyrone Pieter Jeynes , Alistair George Draffan , Barbara Frey , Michael John Lilly
发明人： Rosliana Halim , Michael Harding , Richard Hufton , Craig James Morton , Saba Jahangiri , Brett Raymond Pool , Tyrone Pieter Jeynes , Alistair George Draffan , Barbara Frey , Michael John Lilly
IPC分类号： A61K31/5377 , A61K31/416 , A61K31/41 , A61K31/4178 , A61K31/4523 , A61K31/4427 , A61K31/497 , A61K31/427 , A61K31/422 , A61K31/501 , A61K31/4245 , C07D413/04 , C07D231/56 , C07D257/04 , C07D233/54 , C07D211/00 , C07D401/02 , C07D417/02 , C07D261/06 , C07D403/02 , C07D413/02 , C07D271/08
CPC分类号： C07D231/56 , C07D401/04 , C07D403/04 , C07D403/12 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/04
摘要： The present invention relates to viral polymerase inhibitors of formula (I), salts, N-oxides, solvates, hydrates, racemates, enantiomers or isomers thereof, processes for their preparation and their use in the treatment of Flaviviridae viral infections such as Hepatitis C virus (HCV) infections:
摘要翻译： 本发明涉及式（I）的病毒聚合酶抑制剂，其盐，N-氧化物，溶剂合物，水合物，外消旋物，对映体或异构体，其制备方法及其在治疗黄病毒病毒感染如丙型肝炎病毒 （HCV）感染：
-
-
-
-
-
-
-
搜索结果
8 条记录 (耗时 0.059 秒)
