Compositions and methods using RNA interference for control of nematodes
    2.
    发明授权
    Compositions and methods using RNA interference for control of nematodes 失效
    使用RNA干扰来控制线虫的组合物和方法

    公开(公告)号:US07622301B2

    公开(公告)日:2009-11-24

    申请号:US10906472

    申请日:2005-02-22

    IPC分类号: C12N15/82 C12N5/10

    摘要: The present invention concerns double stranded RNA compositions and transgenic plants capable of inhibiting expression of essential genes in parasitic nematodes, and methods associated therewith. Specifically, the invention relates to the use of RNA interference to inhibit expression of a target essential parasitic nematode gene selected from the group consisting of a parasitic nematode cytosolic chaperonin gene, a parasitic nematode gene encoding heat shock protein-90, a parasitic nematode gene homologous to the C. elegans Y65B4BR.5a gene, and a parasitic nematode gene homologous to a C. elegans pat-10 gene, and relates to the generation of plants that have increased tolerance to parasitic nematodes.

    摘要翻译: 本发明涉及能够抑制寄生线虫中必需基因表达的双链RNA组合物和转基因植物及其相关方法。 具体地说,本发明涉及使用RNA干扰抑制靶寄生线虫基因的表达,该基因选自寄生线虫胞质伴侣蛋白基因,编码热休克蛋白90的寄生线虫基因,寄生线虫基因同源 到线虫Y65B4BR.5a基因,以及与秀丽隐杆线虫pat-10基因同源的寄生线虫基因,涉及对寄生线虫具有增加的耐受性的植物的产生。