摘要:
The present invention relates to 5-sulfonamido substituted indolinones that modulate the activity of protein kinases (“PKs”). The compounds of this invention are therefore useful in treating disorders related to abnormal PK activity. Pharmaceutical compositions comprising these compounds, methods of treating diseases utilizing pharmaceutical compositions comprising these compounds and methods of preparing them are also disclosed.
摘要:
The present invention relates to pyrrole substituted 2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.
摘要:
The present invention relates to pyrrole substituted-2-indolinone compounds and their pharmaceutically acceptable salts which modulate the activity of protein kinases and therefore are expected to be useful in the prevention and treatment of protein kinase related cellular disorders such as cancer.
摘要:
An instrument panel assembly and method of installing an instrument panel assembly is provided. The instrument panel assembly includes a base having a side portion. The side portion includes a first mounting aperture. A side panel is dimensioned to cover the side portion. The side panel is configured to be angled relative to the side portion so as to preventing other tabs from scratching the exterior surface of the instrument panel assembly.
摘要:
An instrument panel assembly and method of installing an instrument panel assembly is provided. The instrument panel assembly includes a base having a side portion. The side portion includes a first mounting aperture. A side panel is dimensioned to cover the side portion. The side panel is configured to be angled relative to the side portion so as to preventing other tabs from scratching the exterior surface of the instrument panel assembly.
摘要:
Hot products of combustion are provided beside an outer surface of a load to be heated, and are given a non-uniform temperature profile in a control direction extending across the outer surface of the load. The non-uniform temperature profile of the hot products of combustion is varied within a range that is predetermined relative to the distance that the outer surface of the load extends in the control direction, whereby the load can be given a predetermined temperature profile in the control direction.
摘要:
Each of two end sections and one middle section of the present basket form is formed with a centrally and axially disposed passageway and with a pair of diametrically opposing passageways spaced radially outwardly from the central passageway. All of the passageways in one of the sections are simultaneously alignable with corresponding passageways in the other sections. The central passageways are adapted to receive a mounting member. Each of the radially outwardly disposed passageways are adapted to receive a bolt, and a wing nut is tightened onto an outwardly projecting threaded end of each bolt to hold the separable sections of the form in alignment with one another. The middle section of the form may be removed and the two end sections held in alignment with one another to accommodate a shallower basket.
摘要:
A request for content is received at a content filter of a computer system, and a determination is made, based on a referrer included in the request, regarding a root site directly or indirectly associated with the request. Thereafter, the content is permitted or not permitted according to whether or not the root site is a permitted site and a site associated with the content is categorized in a semantically equivalent content category with the root site. The determination regarding the root site may involve consulting a referrer chain cache storing lists of referrers which associate referring Web sites with root sites from which referrals originate.