公开(公告)号：US10966447B2

公开(公告)日：2021-04-06

申请号：US15213859

申请日：2016-07-19

Applicant: PepsiCo, Inc.

Inventor： Shawn Erickson ,  Yu-Wen Feng ,  Christophe Galopin ,  Stephen Gravina ,  Yuliya Kurash ,  Thomas Lee ,  Laura Nattress ,  Ting Wang

IPC: A23L27/30 ,  A23L27/00 ,  A23L2/56 ,  A23L29/30 ,  A23L2/60 ,  A23L2/68 ,  C07H15/203

Abstract: The present disclosure provides novel sweetener compositions comprising a compound having a structure according to Formula I: wherein R1, R2, R3, and R4 are described herein. Also provided are methods of modulating sweetness profile of a product by adding a compound of Formula I to the product, such as a beverage product or a food product. For example, the compound described herein can be added to increase the overall sweetness of a nutritive sweetener sweetened beverages; decrease the sweetness time-of-onset for high potency sweeteners such as rebaudioside A; decreasing bitter, metallic and licorice off-notes of high potency sweeteners; and improve the sweet quality of sweetened products.

公开(公告)号：US10107794B2

公开(公告)日：2018-10-23

申请号：US14890049

申请日：2014-05-09

Applicant: PepsiCo, Inc.

Inventor： Yuliya Kurash ,  Stephen Gravina

IPC: G01N33/50 ,  C07K14/43 ,  C07K14/47 ,  C07K14/705 ,  G01N33/74 ,  C07K14/435

Abstract: Co-expression of T1R2 and T1R3 results in a taste receptor that responds to sweet taste stimuli, including naturally occurring and artificial sweeteners. Cells such as U2-OS, which express a functional sweet receptor, can be used in cell-based assays to detect cellular responses to tastants.

公开(公告)号：US09766236B2

公开(公告)日：2017-09-19

申请号：US14890054

申请日：2014-05-09

Applicant: PepsiCo, Inc.

Inventor： Yuliya Kurash ,  Stephen Gravina

IPC: G01N33/566 ,  C07K14/705

CPC classification number: G01N33/566 ,  C07K14/705 ,  G01N2500/10

Abstract: This disclosure provides a taste receptor internalization assay useful for identifying taste modulators.