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公开(公告)号:US20080095776A1
公开(公告)日:2008-04-24
申请号:US11834122
申请日:2007-08-06
申请人: Peter DEVRIES , David OSTROW , Edward REILLY , Larry GREEN , James WEILER
发明人: Peter DEVRIES , David OSTROW , Edward REILLY , Larry GREEN , James WEILER
CPC分类号: C07K16/2863 , C07K2317/21 , C07K2317/74 , C07K2317/92
摘要: The present invention relates to antibodies and antibody fragments thereof that bind to and activate an erythropoietin receptor. The present invention also relates to methods of modulating the endogenous activity of an erythropoietin receptor in a mammal using said antibodies as well as pharmaceutical compositions containing said antibodies.
摘要翻译: 本发明涉及结合并激活促红细胞生成素受体的抗体及其抗体片段。 本发明还涉及使用所述抗体以及含有所述抗体的药物组合物调节哺乳动物中促红细胞生成素受体的内源性活性的方法。