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    Ceramic-coated metal implants
    1.
    发明授权
    Ceramic-coated metal implants 失效
    陶瓷涂层金属植入物

    公开(公告)号：US4846837A

    公开(公告)日：1989-07-11

    申请号：US196851

    申请日：1988-05-16

    申请人： Peter Kurze ,  Waldemar Krysmann ,  Wolfram Knoefler ,  Hans-Ludwig Graf

    发明人： Peter Kurze ,  Waldemar Krysmann ,  Wolfram Knoefler ,  Hans-Ludwig Graf

    IPC分类号： A61L27/00 ,  A61F2/00 ,  A61F2/30 ,  A61F2/32 ,  A61L27/32

    CPC分类号： A61F2/30767 ,  A61L27/32 ,  A61F2/3094 ,  A61F2/32 ,  A61F2002/30906 ,  A61F2002/30925 ,  A61F2310/00023 ,  A61F2310/00598 ,  A61F2310/00616 ,  A61F2310/00796

    摘要： A ceramic-coated metal implant is used in medicine as a hemiprosthesis or endoprosthesis. A metal implant base body having at least a surface comprised of a barrier layer metal is imparted with a surface roughness of 100-400 .mu.m by means of a mechanical and/or chemical and/or electrochemical pretreatment, thereby increasing the effective surface by more than 400%. Using anodic oxidation through spark discharge in aqueous electrolytes, an outer thickness of the roughened barrier layer metal is converted into a ceramic layer comprising oxides of the barrie layer metal and, optionally, a resorbable calcium phosphate. A maximum amount of calcium phosphate ceramic in the oxide layer faces an implantation bed of the implant. The calcium phosphate ceramic concentration decreases in the direction towards the phase boundary of the base body and oxide layer, so that bone can grow into the ceramic-coated metal implant and attain a high tenacity. In order to attain characteristics which are specific to bone, an after treatment in specific media, such as, for example, amino acids or antibiotics, can be performed. The implant can remain in place for a long period, is highly compatible with tissue and provides a large surface of bone contact, which automatically regulates bone growth in accordance with healing and growth processes.

    摘要翻译： 陶瓷涂覆的金属植入物用于医学中作为假体或假体。 通过机械和/或化学和/或电化学预处理，至少具有由阻挡层金属构成的表面的金属植入物基体具有100-400μm的表面粗糙度，从而通过更多的方式增加有效表面 超过400％。 通过在水性电解质中通过火花放电进行阳极氧化，将粗糙化的阻挡层金属的外部厚度转变为包含巴里层金属的氧化物和任选的可再吸收的磷酸钙的陶瓷层。 氧化物层中最大量的磷酸钙陶瓷面向植入物的植入床。 磷酸钙陶瓷浓度在朝向基体和氧化物层的相边界的方向上降低，使得骨可以生长成陶瓷涂覆的金属植入物并获得高韧性。 为了获得对骨特异性的特性，可以在特定培养基（例如氨基酸或抗生素）中进行后处理。 植入物可以长时间保持在适当位置，与组织高度相容，并提供大的骨接触表面，其根据愈合和生长过程自动调节骨生长。