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公开(公告)号：US5104650A
公开(公告)日：1992-04-14
申请号：US99872
申请日：1987-09-22
申请人： Peter Ralph , Mary K. Warren , Kong T. Chong , James J. Devlin , Robert Zimmerman , Ada H. C. Kung
发明人： Peter Ralph , Mary K. Warren , Kong T. Chong , James J. Devlin , Robert Zimmerman , Ada H. C. Kung
CPC分类号： C12N15/73 , C07K14/53 , A61K38/00 , Y10S514/885 , Y10S514/889
摘要： A colony stimulating factor, CSF-1, is a lymphokine useful in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein.
摘要翻译： 集落刺激因子CSF-1是可用于克服化疗诱导的免疫抑制或由其他原因引起的淋巴因子。 通过重组方法获得可用量的CSF-1，包括克隆和表达编码该蛋白质的鼠和人DNA序列。
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公开(公告)号：US5725850A
公开(公告)日：1998-03-10
申请号：US371924
申请日：1995-01-11
申请人： Peter Ralph , Kong T. Chong , James Devlin , Robert Zimmerman , Sharon Lea Aukerman , David B. Ring , Sylvia Hsieh Ma
发明人： Peter Ralph , Kong T. Chong , James Devlin , Robert Zimmerman , Sharon Lea Aukerman , David B. Ring , Sylvia Hsieh Ma
CPC分类号： C12N15/73 , A61K38/18 , A61K38/20 , C07K14/53 , A61K38/00 , Y10S514/885 , Y10S514/887
摘要： A colony stimulating factor, CSF-1, is a lymphokine useful in treating or preventing bacterial, viral or fungal infections, neoplasms, leukopenia, wounds, and in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein.
摘要翻译： 集落刺激因子CSF-1是可用于治疗或预防细菌，病毒或真菌感染，肿瘤，白细胞减少症，伤口和克服化疗诱导的免疫抑制或由其他原因引起的淋巴因子。 通过重组方法获得可用量的CSF-1，包括克隆和表达编码该蛋白质的鼠和人DNA序列。
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公开(公告)号：US5422105A
公开(公告)日：1995-06-06
申请号：US204801
申请日：1994-03-01
申请人： Peter Ralph , Kong T. Chong
发明人： Peter Ralph , Kong T. Chong
CPC分类号： C12N15/73 , A61K31/4174 , A61K31/4196 , A61K31/496 , A61K31/513 , A61K31/7048 , A61K38/193 , A61K45/06 , C07K14/53 , A61K38/00
摘要： A colony stimulating factor, CSF-1, is a lymphokine useful in treating or preventing bacterial, vital or fungal infections, neoplasms, leukopenia, wounds, and in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein.
摘要翻译： 集落刺激因子CSF-1是可用于治疗或预防细菌，重要或真菌感染，肿瘤，白细胞减少症，伤口和克服化疗诱导的免疫抑制或由其他原因引起的淋巴因子。 通过重组方法获得可用量的CSF-1，包括克隆和表达编码该蛋白质的鼠和人DNA序列。
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公开(公告)号：US5837229A
公开(公告)日：1998-11-17
申请号：US371805
申请日：1995-01-11
申请人： Peter Ralph , Kong T. Chong
发明人： Peter Ralph , Kong T. Chong
CPC分类号： C12N15/73 , A61K38/193 , A61K45/06 , C07K14/53 , A61K38/00 , Y10S514/885
摘要： A colony stimulating factor, CSF-1, is a lymphokine useful in treating or preventing bacterial, viral or fungal infections, neoplasms, leukopenia, wounds, and in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein.
摘要翻译： 集落刺激因子CSF-1是可用于治疗或预防细菌，病毒或真菌感染，肿瘤，白细胞减少症，伤口和克服化疗诱导的免疫抑制或由其他原因引起的淋巴因子。 通过重组方法获得可用量的CSF-1，包括克隆和表达编码该蛋白质的鼠和人DNA序列。
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公开(公告)号：US5635175A
公开(公告)日：1997-06-03
申请号：US371804
申请日：1995-01-11
申请人： Peter Ralph , Kong T. Chong
发明人： Peter Ralph , Kong T. Chong
CPC分类号： C12N15/73 , A61K38/18 , A61K38/20 , C07K14/53 , A61K38/00 , Y10S514/885 , Y10S514/887
摘要： A colony stimulating factor, CSF-1, is a lymphokine useful in treating or preventing bacterial, viral or fungal infections, neoplasms, leukopenia, wounds, and in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein.
摘要翻译： 集落刺激因子CSF-1是可用于治疗或预防细菌，病毒或真菌感染，肿瘤，白细胞减少症，伤口和克服化疗诱导的免疫抑制或由其他原因引起的淋巴因子。 通过重组方法获得可用量的CSF-1，包括克隆和表达编码该蛋白质的鼠和人DNA序列。
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公开(公告)号：US5614183A
公开(公告)日：1997-03-25
申请号：US371803
申请日：1995-01-11
申请人： Peter Ralph , Kong T. Chong
发明人： Peter Ralph , Kong T. Chong
CPC分类号： C12N15/73 , A61K38/18 , A61K38/20 , C07K14/53 , A61K38/00 , Y10S514/885 , Y10S514/887
摘要： A colony stimulating factor, CSF-1, is a lymphokine useful in treating or preventing bacterial, viral or fungal infections, neoplasms, leukopenia, wounds, and in overcoming the immunosuppression induced by chemotherapy or resulting from other causes. CSF-1 is obtained in usable amounts by recombinant methods, including cloning and expression of the murine and human DNA sequences encoding this protein.
摘要翻译： 集落刺激因子CSF-1是可用于治疗或预防细菌，病毒或真菌感染，肿瘤，白细胞减少症，伤口和克服化疗诱导的免疫抑制或由其他原因引起的淋巴因子。 通过重组方法获得可用量的CSF-1，包括克隆和表达编码该蛋白质的鼠和人DNA序列。
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