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1.发明授权Methods and systems for protecting critical structures during radiation treatment 有权辐射治疗过程中保护关键结构的方法和系统公开(公告)号：US08421038B2
公开(公告)日：2013-04-16
申请号：US13166957
申请日：2011-06-23
IPC分类号： A61N5/00
CPC分类号： A61N5/1031
摘要： Methods and systems are provided for protecting a critical structure during the administration of radiation treatment to a patient. A register receives proposed positions for one or more radiation beams with respect to a critical structure. A processor predicts a cumulative dose volume for the critical structure based on the dose distribution, and determines if the cumulative dose volume exceeds a tolerance value. If the cumulative dose volume exceeds the tolerance value, the dose distribution may be translated at least in part based on a relationship between the cumulative dose volume and the dose distribution position.
摘要翻译： 提供了在向患者施用放射治疗期间保护临界结构的方法和系统。 寄存器接收关于关键结构的一个或多个辐射束的建议位置。 处理器基于剂量分布预测临界结构的累积剂量体积，并确定累积剂量体积是否超过容差值。 如果累积剂量体积超过耐受值，则可以至少部分地基于累积剂量体积和剂量分布位置之间的关系来翻译剂量分布。
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2.发明申请Methods and Systems for Protecting Critical Structures During Radiation Treatment 有权辐射治疗过程中保护关键结构的方法与系统公开(公告)号：US20120326057A1
公开(公告)日：2012-12-27
申请号：US13166957
申请日：2011-06-23
IPC分类号： A61N5/10
CPC分类号： A61N5/1031
摘要： Methods and systems are provided for protecting a critical structure during the administration of radiation treatment to a patient. A register receives proposed positions for one or more radiation beams with respect to a critical structure. A processor predicts a cumulative dose volume for the critical structure based on the dose distribution, and determines if the cumulative dose volume exceeds a tolerance value. If the cumulative dose volume exceeds the tolerance value, the dose distribution may be translated at least in part based on a relationship between the cumulative dose volume and the dose distribution position.
摘要翻译： 提供了在向患者施用放射治疗期间保护临界结构的方法和系统。 寄存器接收关于关键结构的一个或多个辐射束的建议位置。 处理器基于剂量分布预测临界结构的累积剂量体积，并确定累积剂量体积是否超过容差值。 如果累积剂量体积超过耐受值，则可以至少部分地基于累积剂量体积和剂量分布位置之间的关系来翻译剂量分布。
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公开(公告)号：US08331526B2
公开(公告)日：2012-12-11
申请号：US12600386
申请日：2007-05-17
申请人： Marcel van Herk , Jan-Jakob Sonke , Lambert Zijp , Peter Remeijer
发明人： Marcel van Herk , Jan-Jakob Sonke , Lambert Zijp , Peter Remeijer
CPC分类号： G06T11/006 , G06T2211/412 , G06T2211/421 , G06T2211/428
摘要： An in-line 4D cone beam CT reconstruction algorithm queues a limited number of projection images such that the phase determination algorithm can look-ahead. At regular intervals, the queue is scanned and those images which have enough look-ahead to obtain phase information are filtered and back-projected. The algorithm thus keeps up with the image acquisition speed and produces a 4D reconstruction within a few seconds of the end of scanning.
摘要翻译： 在线4D锥形束CT重建算法对有限数量的投影图像进行排队，使得相位确定算法能够预览。 定期扫描队列，并对具有足够预先获取相位信息的图像进行过滤和反投影。 因此，该算法保持了图像采集速度，并在扫描结束后几秒钟内产生了4D重建。
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公开(公告)号：US08442294B2
公开(公告)日：2013-05-14
申请号：US12601442
申请日：2007-05-31
申请人： Jan-Jakob Sonke , Marcel van Herk , Peter Remeijer
发明人： Jan-Jakob Sonke , Marcel van Herk , Peter Remeijer
CPC分类号： G06T7/20 , G06T5/003 , G06T2207/10116 , G06T2207/20068 , G06T2207/30004
摘要： An example of sporadic motion that causes difficulty in CT scanning is gas pockets moving around the rectum. The invention allows the automatic detection of such movements, by enhancing low density features around the prostate in the individual X-ray images, projecting these features on the cranio-caudal axis (assuming that the gas predominantly moves in this direction) to form a 1-dimensional image, and combining successive ID projections to form a 2D image. Moving gas will produce tilted lines in this image, identifying an angular range that needs to be discarded. Such a process can be used in an image processing apparatus of a CT scanner.
摘要翻译： 导致CT扫描困难的散发运动的一个例子是气囊围绕直肠运动。 本发明允许通过增强各个X射线图像中的前列腺周围的低密度特征来自动检测这种运动，将这些特征投影在头尾尾轴上（假定气体主要在该方向上移动）以形成1 并且将连续的ID投影组合以形成2D图像。 移动气体将在该图像中产生倾斜的线，识别需要丢弃的角度范围。 这样的处理可以用在CT扫描器的图像处理装置中。
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公开(公告)号：US20100166286A1
公开(公告)日：2010-07-01
申请号：US12601442
申请日：2007-05-31
申请人： Jan-Jakob Sonke , Marcel van Herk , Peter Remeijer
发明人： Jan-Jakob Sonke , Marcel van Herk , Peter Remeijer
CPC分类号： G06T7/20 , G06T5/003 , G06T2207/10116 , G06T2207/20068 , G06T2207/30004
摘要： An example of sporadic motion that causes difficulty in CT scanning is gas pockets moving around the rectum. The invention allows the automatic detection of such movements, by enhancing low density features around the prostate in the individual X-ray images, projecting these features on the cranio-caudal axis (assuming that the gas predominantly moves in this direction) to form a 1-dimensional image, and combining successive ID projections to form a 2D image. Moving gas will produce tilted lines in this image, identifying an angular range that needs to be discarded. Such a process can be used in an image processing apparatus of a CT scanner.
摘要翻译： 导致CT扫描困难的散发运动的一个例子是气囊围绕直肠移动。 本发明允许通过增强各个X射线图像中的前列腺周围的低密度特征来自动检测这种运动，将这些特征投影在头尾尾轴上（假定气体主要在该方向上移动）以形成1 并且将连续的ID投影组合以形成2D图像。 移动气体将在该图像中产生倾斜的线，识别需要丢弃的角度范围。 这样的处理可以用在CT扫描器的图像处理装置中。
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公开(公告)号：US07356112B2
公开(公告)日：2008-04-08
申请号：US11531471
申请日：2006-09-13
IPC分类号： G21N23/083
CPC分类号： G06T5/009 , A61N5/1064 , G06T5/003 , G06T7/0016 , G06T7/20 , G06T11/005 , G06T2207/10081 , G06T2207/20068 , G06T2207/20192 , G06T2207/30061 , G06T2207/30096 , G06T2211/412
摘要： Artifacts in the reconstructed volume data of cone beam CT systems can be removed by the application of respiration correlation techniques to the acquired projection images. To achieve this, the phase of the patients breathing is monitored while acquiring projection images continuously. On completion of the acquisition, projection images that have comparable breathing phases can be selected from the complete set, and these are used to reconstruct the volume data using similar techniques to those of conventional CT. Any phase can be selected and therefore the effect of breathing can be studied. It is also possible to use a feature in the projection images such as the patient's diaphragm to determine the breathing phase. This feature in the projection images can be used to control delivery of therapeutic radiation dependent on the patient's breathing cycle, to ensure that the tumor is in the correct position when the radiation is delivered.
摘要翻译： 通过对所获取的投影图像应用呼吸相关技术，可以去除锥束CT系统的重建体数据中的伪像。 为了实现这一点，在持续拍摄投影图像的同时监测患者呼吸的阶段。 完成采集后，可以从完整组中选择具有相似呼吸相位的投影图像，并使用与常规CT类似的技术来重建体积数据。 可以选择任何相位，因此可以研究呼吸的效果。 也可以使用诸如患者隔膜的投影图像中的特征来确定呼吸阶段。 投影图像中的该特征可以用于控制取决于患者呼吸周期的治疗辐射的传递，以确保当辐射被递送时肿瘤处于正确的位置。
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公开(公告)号：US07349564B2
公开(公告)日：2008-03-25
申请号：US10760628
申请日：2004-01-20
申请人： Lambert Zijp , Kevin John Brown , David Jaffray , Jeffrey H. Siewerdsen , Marcel van Herk , Jan-Jakob Sonke
发明人： Lambert Zijp , Kevin John Brown , David Jaffray , Jeffrey H. Siewerdsen , Marcel van Herk , Jan-Jakob Sonke
IPC分类号： G06K9/00
CPC分类号： G06T5/009 , A61N5/1064 , G06T5/003 , G06T7/0016 , G06T7/20 , G06T11/005 , G06T2207/10081 , G06T2207/20068 , G06T2207/20192 , G06T2207/30061 , G06T2207/30096 , G06T2211/412
摘要： An apparatus, method and software module for selecting phase-correlated images from the output of a scanner such as a cone beam CT scanner operates by collapsing the images derived from the series from two dimensions to one dimension by summing the intensities of pixels along a dimension transverse to the one dimension, producing a further image from a composite of the one-dimensional images obtained from images in the series, analysing the further image for periodic patterns, and selecting from the series images having like phase in that periodic pattern. If desired, a plurality of reconstructions can be derived at different phases. The analysis of the further image for periodic patterns can include comparing the one-dimensional images therein, to identify a movement of features in that dimension. This allows (inter alia) the accurate determination of the breathing cycle in a patient and a concomitant improvement in the quality of CT scans by using phase-correlated images.
摘要翻译： 用于从诸如锥形束CT扫描仪的扫描仪的输出中选择相位相关图像的装置，方法和软件模块通过将沿着维度的像素的强度相加而将从二维导出的图像从二维折叠到一维来进行操作 横向于一个维度，从从该系列中的图像获得的一维图像的合成中产生另外的图像，分析另外的图像用于周期性图案，并从具有该周期性图案的类似相位的系列图像中进行选择。 如果需要，可以在不同的阶段导出多个重建。 对于周期性图案的另外的图像的分析可以包括比较其中的一维图像，以识别该维度中的特征的运动。 这允许（特别地）通过使用相位相关图像来准确地确定患者的呼吸周期和伴随的CT扫描质量的改善。
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公开(公告)号：US20070025496A1
公开(公告)日：2007-02-01
申请号：US11531471
申请日：2006-09-13
CPC分类号： G06T5/009 , A61N5/1064 , G06T5/003 , G06T7/0016 , G06T7/20 , G06T11/005 , G06T2207/10081 , G06T2207/20068 , G06T2207/20192 , G06T2207/30061 , G06T2207/30096 , G06T2211/412
摘要： Artifacts in the reconstructed volume data of cone beam CT systems can be removed by the application of respiration correlation techniques to the acquired projection images. To achieve this, the phase of the patients breathing is monitored while acquiring projection images continuously. On completion of the acquisition, projection images that have comparable breathing phases can be selected from the complete set, and these are used to reconstruct the volume data using similar techniques to those of conventional CT. Any phase can be selected and therefore the effect of breathing can be studied. It is also possible to use a feature in the projection images such as the patient's diaphragm to determine the breathing phase. This feature in the projection images can be used to control delivery of therapeutic radiation dependent on the patient's breathing cycle, to ensure that the tumor is in the correct position when the radiation is delivered.
摘要翻译： 通过对所获取的投影图像应用呼吸相关技术，可以去除锥束CT系统的重建体数据中的伪像。 为了实现这一点，在持续拍摄投影图像的同时监测患者呼吸的阶段。 完成采集后，可以从完整组中选择具有相似呼吸相位的投影图像，并使用与常规CT类似的技术来重建体积数据。 可以选择任何相位，因此可以研究呼吸的效果。 也可以使用诸如患者隔膜的投影图像中的特征来确定呼吸阶段。 投影图像中的该特征可以用于控制取决于患者呼吸周期的治疗辐射的传递，以确保当辐射被递送时肿瘤处于正确的位置。
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