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![Manufacturing process and intermediates for a pyrrolo[2,3-d]pyrimidine compound and use thereof](/abs-image/US/2022/02/22/US11254684B2/abs.jpg.150x150.jpg)
1.发明授权公开(公告)号：US11254684B2
公开(公告)日：2022-02-22
申请号：US17036849
申请日：2020-09-29
Applicant: Pfizer Inc.
Inventor： Kapildev Kashmirilal Arora , Jacob Cole DeForest , Andrew Kevern Hills , Brian Patrick Jones , Kris Nicole Jones , Chad Arthur Lewis , Anil Mahadeo Rane
IPC: C07D487/04 , C07D249/08
Abstract: The present invention relates to a manufacturing process and intermediates for preparing a crystalline or non-crystalline form of N-((1S,3S)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide. The present invention also relates to salt forms and pharmaceutical compositions comprising the crystalline form, and to methods for use of the compound prepared from a crystalline form in the treatment of various diseases.
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Patent Agency Ranking
![Manufacturing process and intermediates for a pyrrolo[2,3-d]pyrimidine compound and use thereof](/abs-image/US/2020/10/27/US10815240B2/abs.jpg.150x150.jpg)
2.发明授权公开(公告)号：US10815240B2
公开(公告)日：2020-10-27
申请号：US16502703
申请日：2019-07-03
Applicant: Pfizer Inc.
Inventor： Kapildev Kashmirilal Arora , Jacob Cole DeForest , Andrew Kevern Hills , Brian Patrick Jones , Kris Nicole Jones , Chad Arthur Lewis , Anil Mahadeo Rane
IPC: C07D487/04 , C07D249/08
Abstract: The present invention relates to a manufacturing process and intermediates for preparing a crystalline or non-crystalline form of N-((1S,3S)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide. The present invention also relates to salt forms and pharmaceutical compositions comprising the crystalline form, and to methods for use of the compound prepared from a crystalline form in the treatment of various diseases.
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![MANUFACTURING PROCESS AND INTERMEDIATES FOR A PYRROLO[2,3-D]PYRIMIDINE COMPOUND AND USE THEREOF](/abs-image/US/2021/01/14/US20210009601A1/abs.jpg.150x150.jpg)
3.发明申请公开(公告)号：US20210009601A1
公开(公告)日：2021-01-14
申请号：US17036849
申请日：2020-09-29
Applicant: Pfizer Inc.
Inventor： Kapildev Kashmirilal Arora , Jacob Cole DeForest , Andrew Kevern Hills , Brian Patrick Jones , Kris Nicole Jones , Chad Arthur Lewis , Anil Mahadeo Rane
IPC: C07D487/04 , C07D249/08
Abstract: The present invention relates to a manufacturing process and intermediates for preparing a crystalline or non-crystalline form of N-((1S,3S)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide. The present invention also relates to salt forms and pharmaceutical compositions comprising the crystalline form, and to methods for use of the compound prepared from a crystalline form in the treatment of various diseases.
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![MANUFACTURING PROCESS AND INTERMEDIATES FOR A PYRROLO[2,3-D]PYRIMIDINE COMPOUND AND USE THEREOF](/abs-image/US/2020/04/23/US20200123159A1/abs.jpg.150x150.jpg)
4.发明申请公开(公告)号：US20200123159A1
公开(公告)日：2020-04-23
申请号：US16502703
申请日：2019-07-03
Applicant: Pfizer Inc.
Inventor： Kapildev Kashmirilal Arora , Jacob Cole DeForest , Andrew Kevern Hills , Brian Patrick Jones , Kris Nicole Jones , Chad Arthur Lewis , Anil Mahadeo Rane
IPC: C07D487/04 , C07D249/08
Abstract: The present invention relates to a manufacturing process and intermediates for preparing a crystalline or non-crystalline form of N-((1S,3S)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide. The present invention also relates to salt forms and pharmaceutical compositions comprising the crystalline form, and to methods for use of the compound prepared from a crystalline form in the treatment of various diseases.
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![Manufacturing process and intermediates for a pyrrolo[2,3-d]pyrimidine compound and use thereof](/abs-image/US/2024/06/25/US12018031B2/abs.jpg.150x150.jpg)
5.发明授权公开(公告)号：US12018031B2
公开(公告)日：2024-06-25
申请号：US17572089
申请日：2022-01-10
Applicant: Pfizer Inc.
Inventor： Kapildev Kashmirilal Arora , Jacob Cole DeForest , Andrew Kevern Hills , Brian Patrick Jones , Kris Nicole Jones , Chad Arthur Lewis , Anil Mahadeo Rane
IPC: C07D487/04 , C07D249/08
CPC classification number: C07D487/04 , C07D249/08 , C07B2200/13
Abstract: The present invention relates to a manufacturing process and intermediates for preparing a crystalline or non-crystalline form of N-((1S,3S)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide. The present invention also relates to salt forms and pharmaceutical compositions comprising the crystalline form, and to methods for use of the compound prepared from a crystalline form in the treatment of various diseases.
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![MANUFACTURING PROCESS AND INTERMEDIATES FOR A PYRROLO[2,3-D]PYRIMIDINE COMPOUND AND USE THEREOF](/abs-image/US/2022/04/28/US20220127274A1/abs.jpg.150x150.jpg)
6.发明申请公开(公告)号：US20220127274A1
公开(公告)日：2022-04-28
申请号：US17572089
申请日：2022-01-10
Applicant: Pfizer Inc.
Inventor： Kapildev Kashmirilal Arora , Jacob Cole DeForest , Andrew Kevern Hills , Brian Patrick Jones , Kris Nicole Jones , Chad Arthur Lewis , Anil Mahadeo Rane
IPC: C07D487/04 , C07D249/08
Abstract: The present invention relates to a manufacturing process and intermediates for preparing a crystalline or non-crystalline form of N-((1S,3S)-3-(methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)cyclobutyl)propane-1-sulfonamide. The present invention also relates to salt forms and pharmaceutical compositions comprising the crystalline form, and to methods for use of the compound prepared from a crystalline form in the treatment of various diseases.
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