公开(公告)号：US20230405137A1

公开(公告)日：2023-12-21

申请号：US18252124

申请日：2021-11-04

Applicant: Pfizer Inc.

Inventor： Paul Wayne Brown ,  Kaushik Dutta ,  Jason Arnold Lotvin ,  Kelly Jeffrey Sackett

IPC: A61K47/64 ,  A61K39/09 ,  A61P31/04

CPC classification number: A61K47/646 ,  A61K39/092 ,  A61P31/04 ,  A61K2039/6037

Abstract: The present invention relates to new immunogenic compositions comprising conjugated Streptococcus pneumoniae capsular saccharide antigens (glycoconjugates), kits comprising said immunogenic compositions and uses thereof. Immunogenic compositions of the present invention will typically comprise at least one glycoconjugate from a S. pneumoniae serotype not found in PREVNAR®, SYNFLORIX® and/or PREVNAR 13®. The invention also relates to vaccination of human subjects, in particular infants and elderly, against pneumococcal infections using said novel immunogenic compositions.