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公开(公告)号：US20170072066A1
公开(公告)日：2017-03-16
申请号：US15176452
申请日：2016-06-08
Applicant: PFIZER, INC. , STEMCENTRX, INC.
Inventor： Marc Isaac DAMELIN , Kiran Manohar KHANDKE , Puja SAPRA , Alexander John BANKOVICH , Scott J. DYLLA
IPC: A61K47/48 , C07K16/30 , A61K31/704
CPC classification number: A61K47/6849 , A61K31/704 , A61K47/6807 , A61K47/6851 , C07K16/30 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/77
Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
Abstract translation: 本发明提供抗EFNA4抗体 - 药物偶联物及其制备和使用方法。
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公开(公告)号：US20200377615A1
公开(公告)日：2020-12-03
申请号：US16891460
申请日：2020-06-03
Applicant: Pfizer Inc.
Inventor： Dangshe MA , Frank LOGANZO, Jr. , Kimberly Ann MARQUETTE , Edmund Idris GRAZIANI , Puja SAPRA , Pavel STROP
Abstract: The present invention provides site specific HER2 antibody drug conjugates and methods for preparing and using the same.
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公开(公告)号：US20200069764A1
公开(公告)日：2020-03-05
申请号：US16688173
申请日：2019-11-19
Applicant: Pfizer Inc.
Inventor： Dangshe MA , Kimberly Ann MARQUETTE , Edmund Idris GRAZIANI , Puja SAPRA , Lawrence Nathan TUMEY , Nadira Anarkali PRASHAD , Kiran Manohar KHANDKE , Eric M. BENNETT , Lioudmila TCHISTIAKOVA
Abstract: The invention relates to polypeptides, antibodies, and antigen-binding fragments thereof, that comprise a substituted cysteine for site-specific conjugation.
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公开(公告)号：US20170216452A1
公开(公告)日：2017-08-03
申请号：US15356953
申请日：2016-11-21
Applicant: Pfizer Inc.
Inventor： Dangshe MA , Kimberly Ann MARQUETTE , Edmund Idris GRAZIANI , Puja SAPRA , Lawrence Nathan TUMEY , Nadira Anarkali PRASHAD , Kiran Manohar KHANDKE , Eric M. BENNETT , Lioudmila TCHISTIAKOVA
CPC classification number: A61K38/05 , A61K47/6803 , A61K47/6851 , A61K47/6855 , C07K16/283 , C07K16/32 , C07K2317/24 , C07K2317/52 , C07K2317/73 , C07K2317/732 , C07K2317/92 , C07K2317/94
Abstract: The invention relates to polypeptides, antibodies, and antigen-binding fragments thereof, that comprise a substituted cysteine for site-specific conjugation.
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Patent Agency Ranking
公开(公告)号：US20150315293A1
公开(公告)日：2015-11-05
申请号：US14696663
申请日：2015-04-27
Applicant: PFIZER INC. , STEMCENTRX, INC.
Inventor： Marc Isaac DAMELIN , Puja SAPRA , Alexander John BANKOVICH , Scott J. DYLLA
CPC classification number: C07K16/40 , A61K47/6801 , A61K47/6803 , A61K47/6817 , A61K47/6847 , A61K47/6871 , A61K47/6889 , C07K16/30 , C07K2317/24 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/77 , C07K2317/92
Abstract: The present invention provides anti-PTK7 antibody-drug conjugates and methods for preparing and using the same.
Abstract translation: 本发明提供抗PTK7抗体 - 药物偶联物及其制备和使用方法。
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公开(公告)号：US20180296691A1
公开(公告)日：2018-10-18
申请号：US15876402
申请日：2018-01-22
Applicant: PFIZER, INC. , ABBVIE STEMCENTRX LLC
Inventor： Marc Isaac DAMELIN , Kiran Manohar KHANDKE , Puja SAPRA , Alexander John BANKOVICH , Scott J. DYLLA
IPC: A61K47/68 , A61K31/704 , C07K16/30
Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
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公开(公告)号：US20180094075A1
公开(公告)日：2018-04-05
申请号：US15693687
申请日：2017-09-01
Applicant: PFIZER INC. , ABBVIE STEMCENTRX LLC
Inventor： Marc Isaac DAMELIN , Puja SAPRA , Alexander John BANKOVICH , Scott J. DYLLA
CPC classification number: C07K16/40 , A61K47/6801 , A61K47/6803 , A61K47/6817 , A61K47/6847 , A61K47/6871 , A61K47/6889 , C07K16/30 , C07K2317/24 , C07K2317/33 , C07K2317/55 , C07K2317/565 , C07K2317/73 , C07K2317/77 , C07K2317/92
Abstract: The present invention provides anti-PTK7 antibody-drug conjugates and methods for preparing and using the same.
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公开(公告)号：US20170151341A1
公开(公告)日：2017-06-01
申请号：US15356750
申请日：2016-11-21
Applicant: Pfizer Inc.
Inventor： Dangshe MA , Frank LOGANZO, JR. , Kimberly Ann MARQUETTE , Edmund Idris GRAZIANI , Puja SAPRA , Pavel STROP
Abstract: The present invention provides site specific HER2 antibody drug conjugates and methods for preparing and using the same.
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公开(公告)号：US20150125472A1
公开(公告)日：2015-05-07
申请号：US14525442
申请日：2014-10-28
Applicant: Pfizer, Inc. , Stem CentRx, Inc.
Inventor： Marc Isaac DAMELIN , Kiran Manohar KHANDKE , Puja SAPRA , Alexander John BANKOVICH , Scott J. DYLLA
IPC: A61K31/704 , C07K16/30 , A61K47/48
CPC classification number: A61K47/6849 , A61K31/704 , A61K47/6807 , A61K47/6851 , C07K16/30 , C07K2317/24 , C07K2317/34 , C07K2317/565 , C07K2317/76 , C07K2317/77
Abstract: The present invention provides for anti-EFNA4 antibody-drug conjugates and methods for preparing and using the same.
Abstract translation: 本发明提供抗EFNA4抗体 - 药物偶联物及其制备和使用方法。
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