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公开(公告)号：US20100260726A1
公开(公告)日：2010-10-14
申请号：US12740405
申请日：2008-09-30
IPC分类号： A61K35/12 , A01K67/027 , A61K38/18
CPC分类号： A61K38/1841 , A01K2207/10 , A01K2227/105 , A01K2267/0375
摘要： The present invention relates to methods for producing a non human animal model for aortic aneurysm which could provide insight into the diagnosis and treatment of said disease. Furthermore, the present invention relates to methods and compositions for the treatment or the prevention of aneurysm in a subject in need thereof.
摘要翻译： 本发明涉及用于生产用于主动脉瘤的非人动物模型的方法，其可以提供对所述疾病的诊断和治疗的洞察。 此外，本发明涉及用于治疗或预防有需要的受试者的动脉瘤的方法和组合物。
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公开(公告)号：US08586822B2
公开(公告)日：2013-11-19
申请号：US12740405
申请日：2008-09-30
CPC分类号： A61K38/1841 , A01K2207/10 , A01K2227/105 , A01K2267/0375
摘要： The present invention relates to methods for producing a non human animal model for aortic aneurysm which could provide insight into the diagnosis and treatment of disease. Furthermore, the present invention relates to methods and compositions for the treatment or the prevention of aneurysm in a subject in need thereof.
摘要翻译： 本发明涉及用于生产用于主动脉瘤的非人动物模型的方法，其可以提供对疾病的诊断和治疗的洞察。 此外，本发明涉及用于治疗或预防有需要的受试者的动脉瘤的方法和组合物。
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公开(公告)号：US20100104558A1
公开(公告)日：2010-04-29
申请号：US12447498
申请日：2006-10-31
IPC分类号： A61K31/517 , A61P13/12 , A61K31/5377 , A61K31/519 , A61K39/395 , A61K31/7088
CPC分类号： A61K31/47 , A61K31/517 , A61K31/519 , A61K31/5377
摘要： The present invention relates to uses, methods and compositions for treating immune-mediated glomerulonephritis, such as crescentic glomerulonephritis. More specifically, the invention relates to the use of an EFGR antagonist or of an inhibitor of EGFR or HB-EGF expression for the treatment of said diseases.
摘要翻译： 本发明涉及用于治疗免疫介导的肾小球性肾炎如新月体性肾小球肾炎的用途，方法和组合物。 更具体地，本发明涉及EFGR拮抗剂或EGFR或HB-EGF表达抑制剂用于治疗所述疾病的用途。
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公开(公告)号：US08198266B2
公开(公告)日：2012-06-12
申请号：US12447498
申请日：2006-10-31
IPC分类号： A61K31/33
CPC分类号： A61K31/47 , A61K31/517 , A61K31/519 , A61K31/5377
摘要： The present invention relates to uses, methods and compositions for treating immune-mediated glomerulonephritis, such as crescentic glomerulonephritis. More specifically, the invention relates to the use of an EFGR antagonist or of an inhibitor of EGFR or HB-EGF expression for the treatment of said diseases.
摘要翻译： 本发明涉及用于治疗免疫介导的肾小球性肾炎如新月体性肾小球肾炎的用途，方法和组合物。 更具体地，本发明涉及EFGR拮抗剂或EGFR或HB-EGF表达抑制剂用于治疗所述疾病的用途。
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