公开(公告)号：US20140243427A1

公开(公告)日：2014-08-28

申请号：US14348604

申请日：2012-10-01

Applicant: Polyganics B.V.

Inventor： Bhushan Chandrashekhar-Bhat ,  Martin Franke Tooren ,  Robbert Arnold de Graaf ,  Romke Stephan Rudolf Ribbels

IPC: C08G18/08 ,  A61K9/12 ,  A61K47/34

CPC classification number: C08G18/14 ,  A61K9/122 ,  A61K47/34 ,  A61L24/0036 ,  A61L27/56 ,  A61L2400/08 ,  B29C67/202 ,  C08J9/0066 ,  C08J9/0095 ,  C08J9/28 ,  C08J2201/048

Abstract: The invention relates to processes for preparing a synthetic foam having present therein particles with a controlled particle distribution and the use of said foam, as well as to foams as such. Accordingly the invention is directed to a process for preparing a synthetic foam having present therein particles, wherein the distribution of said particles is controlled by the following steps of dissolving at least one synthetic polymer in one or more solvents to form a solution; contacting particles with said solution to form a polymer/particles mixture; and freeze-drying the polymer/particles mixture by: freezing the polymer/particles mixture; and subsequently subliming the one or more solvents to form a synthetic foam comprising said particles.

Abstract translation: 本发明涉及制备合成泡沫的方法，其中存在具有可控颗粒分布的颗粒和所述泡沫的用途以及泡沫。 因此，本发明涉及一种制备其中存在颗粒的合成泡沫体的方法，其中通过以下步骤控制所述颗粒的分布，所述步骤将至少一种合成聚合物溶解在一种或多种溶剂中以形成溶液; 使颗粒与所述溶液接触以形成聚合物/颗粒混合物; 并通过以下方法冷冻干燥聚合物/颗粒混合物：冷冻聚合物/颗粒混合物; 然后升华所述一种或多种溶剂以形成包含所述颗粒的合成泡沫。