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公开(公告)号:US20050228007A1
公开(公告)日:2005-10-13
申请号:US11066824
申请日:2005-02-25
申请人: Prakash Jagtap , Erkan Baloglu , John Van Duzer , Csaba Szabo , Andrew Salzman , Aloka Roy , William Williams , Alexander Nivorozhkin
发明人: Prakash Jagtap , Erkan Baloglu , John Van Duzer , Csaba Szabo , Andrew Salzman , Aloka Roy , William Williams , Alexander Nivorozhkin
IPC分类号: A61K31/473 , A61K31/4745 , A61K31/55 , C07D221/18
CPC分类号: A61K31/473 , A61K31/4745 , A61K31/55 , C07D221/18
摘要: The present invention relates to Isoquinoline Derivatives, compositions comprising an effective amount of a Isoquinoline Derivative and methods for treating or preventing an inflammatory disease, a reperfusion injury, an ischemic condition, renal failure, diabetes, a diabetic complication, a vascular disease other than a cardiovascular disease, cardiovascular disease, reoxygenation injury resulting from organ transplantation, Parkinson's disease, or cancer, comprising administering to an animal in need thereof an effective amount of a Isoquinoline Derivative.
摘要翻译: 本发明涉及异喹啉衍生物,包含有效量的异喹啉衍生物的组合物和治疗或预防炎性疾病,再灌注损伤,缺血状况,肾衰竭,糖尿病,糖尿病并发症,除 心血管疾病,心脏病,由器官移植引起的再氧化损伤,帕金森病或癌症,包括向有需要的动物施用有效量的异喹啉衍生物。
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公开(公告)号:US20080262016A1
公开(公告)日:2008-10-23
申请号:US12140120
申请日:2008-06-16
申请人: Prakash Jagtap , Erkan Baloglu , John H. van Duzer , Csaba Szabo , Andrew L. Salzman , Aloka Roy , William Williams , Alexander Nivorozhkin
发明人: Prakash Jagtap , Erkan Baloglu , John H. van Duzer , Csaba Szabo , Andrew L. Salzman , Aloka Roy , William Williams , Alexander Nivorozhkin
IPC分类号: A61K31/4738 , C07D221/02 , C12N5/00 , A61P9/00 , A61P3/10 , A61P29/00 , A61K31/473
CPC分类号: C07D495/04 , A61K31/435 , A61K31/473 , A61K31/4741 , A61K31/4743 , A61K31/4745 , C07D221/18 , C07D471/04 , C07D491/04 , Y02A50/422
摘要: The invention provides novel classes of Isoquinoline Derivatives. Pharmaceutical compositions and methods of making and using the compounds, are also described.
摘要翻译: 本发明提供了新类别的异喹啉衍生物。 还描述了制备和使用化合物的药物组合物和方法。
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公开(公告)号:US20070249653A1
公开(公告)日:2007-10-25
申请号:US11786627
申请日:2007-04-12
IPC分类号: A61K31/4355 , A61K31/4418 , A61P13/12 , A61P3/10 , A61P9/00
CPC分类号: C07H17/00 , C07D221/18 , C07D471/04 , C07D471/14 , C07D491/04 , C07D495/04 , C07D495/14
摘要: The invention relates to Tetracyclic Benzamide Derivatives; compositions comprising a Tetracyclic Benzamide Derivative; and methods for treating or preventing an inflammatory disease, a reperfusion disease, an ischemic condition, renal failure, diabetes, a diabetic complication, a vascular disease, or cancer, comprising administering to a subject in need thereof an effective amount of a Tetracyclic Benzamide Derivative.
摘要翻译: 本发明涉及四环苯甲酰胺衍生物; 包含四环苯甲酰胺衍生物的组合物; 以及用于治疗或预防炎性疾病,再灌注疾病,缺血性疾病,肾功能衰竭,糖尿病,糖尿病并发症,血管疾病或癌症的方法,包括向有需要的受试者施用有效量的四环苯甲酰胺衍生物 。
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