公开(公告)号：US10591458B2

公开(公告)日：2020-03-17

申请号：US15116258

申请日：2015-02-18

Applicant: President and Fellows of Harvard College

Inventor： Kevin Kit Parker ,  Johan Ulrik Lind ,  Jennifer Ann Lewis ,  Joost Johan Vlassak ,  Hongyan Yuan ,  Travis Alexander Busbee ,  Ian Perkins ,  Christophe Chantre

IPC: G01N33/483 ,  A61B5/00 ,  A61B5/053

Abstract: Embodiments described herein are directed to devices for supporting growth of anisotropic muscle tissue layers and in vitro readout and quantification of force generated by the tissue layers using one or more strain-sensing elements integrated into the device. Embodiments also include multiplexed apparatuses of multiple independent devices, methods of fabricating the devices and apparatuses, and methods of using the devices and apparatuses.

公开(公告)号：US20170016875A1

公开(公告)日：2017-01-19

申请号：US15116258

申请日：2015-02-18

Applicant: President and Fellows of Harvard College

Inventor： Kevin Kit Parker ,  Johan Ulrik Lind ,  Jennifer Ann Lewis ,  Joost Johan Vlassak ,  Hongyan Yuan ,  Travis Alexander Busbee ,  Ian Perkins ,  Christophe Chantre

IPC: G01N33/483

CPC classification number: G01N33/4833 ,  A61B5/053 ,  A61B5/4519

Abstract: Embodiments described herein are directed to devices for supporting growth of anisotropic muscle tissue layers and in vitro readout and quantification of force generated by the tissue layers using one or more strain-sensing elements integrated into the device. Embodiments also include multiplexed apparatuses of multiple independent devices, methods of fabricating the devices and apparatuses, and methods of using the devices and apparatuses.

Abstract translation: 本文描述的实施例涉及用于支持各向异性肌肉组织层的生长的装置，以及使用集成到装置中的一个或多个应变感测元件由组织层产生的力的体外读出和定量。 实施例还包括多个独立设备的复用设备，制造设备和设备的方法以及使用设备和设备的方法。