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公开(公告)号：US20050131338A1
公开(公告)日：2005-06-16
申请号：US11039518
申请日：2005-01-19
申请人： Preston Keusch , NRK Vilambi , Bruce Eliash
发明人： Preston Keusch , NRK Vilambi , Bruce Eliash
CPC分类号： A61N1/0448 , A61N1/0436 , A61N1/044
摘要： A reservoir electrode assembly of the present invention for an iontophoretic drug delivery device includes an electrode and a hydrophilic reservoir situated in electrically conductive relation to the electrode. The hydrophilic reservoir is formed from a bibulous hydrophilic cross-linked polymeric material having a first surface and a second surface that is adhesively adherent to the electrode. The first surface of the polymeric material is releasably adhesively adherent when applied to an area of a patient's skin. The polymeric material has a cohesive strength forms an adhesive bond with a bond strength between the second surface of the polymeric material to the electrode that is greater than the cohesive strength of the polymeric material. Additionally, an adhesive bond strength of the first surface of the polymeric material to the applied area of the patient is less than the cohesive strength of the polymeric material so that upon removal of the reservoir assembly of the invention from the applied area of the patient, substantially no polymeric material remains on the applied area and the hydrophilic reservoir remains substantially intact and adhesively adherent to the electrode.
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2.发明授权公开(公告)号：US06377847B1
公开(公告)日：2002-04-23
申请号：US09328329
申请日：1999-06-09
IPC分类号： A61N130
CPC分类号： A61N1/0448 , A61F2013/0296 , A61N1/0436 , A61N1/044
摘要： A reservoir electrode assembly of the present invention for an iontophoretic drug delivery device includes an electrode and a hydrophilic reservoir situated in electrically conductive relation to the electrode. The hydrophilic reservoir is formed from a bibulous hydrophilic cross-linked polymeric material having a first surface and a second surface that is adhesively adherent to the electrode. The first surface of the polymeric material is releasably adhesively adherent when applied to an area of a patient's skin. The polymeric material has a cohesive strength forms an adhesive bond with a bond strength between the second surface of the polymeric material to the electrode that is greater than the cohesive strength of the polymeric material. Additionally, an adhesive bond strength of the first surface of the polymeric material to the applied area of the patient is less than the cohesive strength of the polymeric material so that upon removal of the reservoir assembly of the invention from the applied area of the patient, substantially no polymeric material remains on the applied area and the hydrophilic reservoir remains substantially intact and adhesively adherent to the electrode.
摘要翻译： 用于离子电渗药物递送装置的本发明的储存器电极组件包括位于与电极导电关系的电极和亲水性储存器。 亲水性储存器由具有第一表面和吸附在电极上的第二表面的吸水性亲水性交联聚合物材料形成。 当应用于患者皮肤区域时，聚合物材料的第一表面可剥离地粘附。 聚合物材料具有内聚强度，其形成粘合剂粘合，聚合物材料的第二表面与电极之间的粘合强度大于聚合物材料的内聚强度。 此外，聚合物材料的第一表面与患者的施用区域的粘合粘合强度小于聚合材料的内聚强度，使得当从患者的施用区域移除本发明的储器组件时， 基本上没有聚合物材料保留在施加的区域上，并且亲水性储存器保持基本上完整且粘附到电极上。
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公开(公告)号：US07043297B2
公开(公告)日：2006-05-09
申请号：US11039518
申请日：2005-01-19
IPC分类号： A61N1/30
CPC分类号： A61N1/0448 , A61N1/0436 , A61N1/044
摘要： A reservoir electrode assembly of the present invention for an iontophoretic drug delivery device includes an electrode and a hydrophilic reservoir situated in electrically conductive relation to the electrode. The hydrophilic reservoir is formed from a bibulous hydrophilic cross-linked polymeric material having a first surface and a second surface that is adhesively adherent to the electrode. The first surface of the polymeric material is releasably adhesively adherent when applied to an area of a patient's skin. The polymeric material has a cohesive strength forms an adhesive bond with a bond strength between the second surface of the polymeric material to the electrode that is greater than the cohesive strength of the polymeric material. Additionally, an adhesive bond strength of the first surface of the polymeric material to the applied area of the patient is less than the cohesive strength of the polymeric material so that upon removal of the reservoir assembly of the invention from the applied area of the patient, substantially no polymeric material remains on the applied area and the hydrophilic reservoir remains substantially intact and adhesively adherent to the electrode.
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