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公开(公告)号：US11047869B2
公开(公告)日：2021-06-29
申请号：US15891793
申请日：2018-02-08
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Livia Schiavinato Eberlin , Christina Ramires Ferreira , Allison Lisa Dill , Demian R. Ifa
Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a tissue sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. Due to the use of a liquid phase that does not destroy native tissue morphology during analysis, a subsequent staining technique can be performed on the tissue sample and an overlaid image can be produced of a mass spectral image and a staining image.
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公开(公告)号：US20240219410A1
公开(公告)日：2024-07-04
申请号：US18394339
申请日：2023-12-22
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Livia Schiavinato Eberlin , Christina Ramires Ferreira , Allison Lisa Dill , Demian R. Ifa
CPC classification number: G01N33/92 , H01J49/0036 , H01J49/165 , H01J49/0004 , H01J49/142
Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis.
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Patent Agency Ranking
公开(公告)号：US20180188273A1
公开(公告)日：2018-07-05
申请号：US15891793
申请日：2018-02-08
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Livia Schiavinato Eberlin , Christina Ramires Ferreira , Allison Lisa Dill , Demian R. Ifa
CPC classification number: G01N33/92 , H01J49/0004 , H01J49/0036 , H01J49/142 , H01J49/165
Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis.
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公开(公告)号：US20160047831A1
公开(公告)日：2016-02-18
申请号：US14880623
申请日：2015-10-12
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Livia Schiavinato Eberlin , Christina Ramires Ferreira , Allison Lisa Dill , Demian R. Ifa
CPC classification number: G01N33/92 , H01J49/0004 , H01J49/0036 , H01J49/142 , H01J49/165
Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis.
Abstract translation: 本发明一般涉及质谱分析。 在某些实施方案中，本发明的方法涉及使用质谱技术分析含脂质样品，其中该技术利用在分析期间不破坏天然组织形态的液相。
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公开(公告)号：US09921233B2
公开(公告)日：2018-03-20
申请号：US14880623
申请日：2015-10-12
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Livia Schiavinato Eberlin , Christina Ramires Ferreira , Allison Lisa Dill , Demian R. Ifa
CPC classification number: G01N33/92 , H01J49/0004 , H01J49/0036 , H01J49/142 , H01J49/165
Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis.
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公开(公告)号：US11860172B2
公开(公告)日：2024-01-02
申请号：US17331264
申请日：2021-05-26
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Livia Schiavinato Eberlin , Christina Ramires Ferreira , Allison Lisa Dill , Demian R. Ifa
CPC classification number: G01N33/92 , H01J49/0036 , H01J49/165 , H01J49/0004 , H01J49/142
Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis. Due to the use of a liquid phase that does not destroy native tissue morphology during analysis, a subsequent staining technique can be performed on the tissue sample and an overlaid image can be produced of a mass spectral image and a staining image.
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公开(公告)号：US20210356480A1
公开(公告)日：2021-11-18
申请号：US17331264
申请日：2021-05-26
Applicant: Purdue Research Foundation
Inventor： Robert Graham Cooks , Livia Schiavinato Eberlin , Christina Ramires Ferreira , Allison Lisa Dill , Demian R. Ifa
Abstract: The invention generally relates to mass spectral analysis. In certain embodiments, methods of the invention involve analyzing a lipid containing sample using a mass spectrometry technique, in which the technique utilizes a liquid phase that does not destroy native tissue morphology during analysis.
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