公开(公告)号：US20160102065A1

公开(公告)日：2016-04-14

申请号：US14973752

申请日：2015-12-18

申请人： Pusan National University Industry-University Cooperation Foundation

发明人： Hae Young CHUNG ,  Hyung Ryong MOON ,  Min Hi PARK ,  Young Mi HA ,  Yun Jung PARK ,  Ji Young PARK ,  Jin Ah KIM ,  Ji Yeon LEE ,  Kyung Jin LEE

IPC分类号： C07D263/42 ,  A61K8/49 ,  C07D207/448 ,  A61Q19/08 ,  C07D239/62 ,  C07D233/96 ,  C07D277/34 ,  A61Q19/02

CPC分类号： C07D263/42 ,  A61K8/49 ,  A61K8/4913 ,  A61K8/4946 ,  A61K8/4953 ,  A61Q19/02 ,  A61Q19/04 ,  A61Q19/08 ,  C07D207/18 ,  C07D207/448 ,  C07D233/96 ,  C07D239/62 ,  C07D277/34

摘要： Provided are a novel compound having skin-whitening, anti-oxidizing and PPAR activities and a medical use thereof, and the compound has skin-whitening activities for the suppression of tyrosinase, and accordingly, is useful for use in skin-whitening pharmaceutical composition or cosmetic products; has anti-oxidant activities, and accordingly, is useful for the prevention and treatment of skin-aging; and has PPAR activities, and in particular, PPARα and PPARγ activities, and accordingly, is useful for use in pharmaceutical compositions or health foods which are effective for the prevention and treatment of obesity, metabolic disease, or cardiovascular disease.