公开(公告)号：US20220000752A1

公开(公告)日：2022-01-06

申请号：US17480436

申请日：2021-09-21

申请人： Q-Med AB

发明人： Åsa Wiebensjö ,  Katarina Edsman

IPC分类号： A61K8/60 ,  A61K8/42 ,  A61K8/67 ,  A61K8/73 ,  A61L27/20 ,  A61L27/54 ,  A61L31/04 ,  A61L31/16 ,  A61Q7/00 ,  A61Q19/08 ,  A61K45/06 ,  A61K31/245 ,  A61K31/375 ,  A61K31/445 ,  A61K31/728 ,  A61K31/167 ,  A61K47/24 ,  A61Q19/00 ,  A61K47/61

摘要： An injectable hyaluronic acid composition including a hyaluronic acid; a local anesthetic selected from the group of amide and ester type local anesthetics or a combination thereof; and an ascorbic acid derivative in an amount which prevents or reduces the effect on the viscosity and/or elastic modulus G′ of the composition caused by the local anesthetic upon sterilization by heat. Further, the medical and non-medical, such as cosmetic, use of such a composition, and to a method of manufacturing such a composition.

公开(公告)号：US20200261343A1

公开(公告)日：2020-08-20

申请号：US16583421

申请日：2019-09-26

申请人： Q-Med AB

发明人： Åsa Wiebensjö ,  Katarina EDSMAN

IPC分类号： A61K8/60 ,  A61K47/61 ,  A61Q19/00 ,  A61K47/24 ,  A61K31/167 ,  A61K31/728 ,  A61K31/445 ,  A61K31/375 ,  A61K31/245 ,  A61K45/06 ,  A61Q19/08 ,  A61Q7/00 ,  A61L31/16 ,  A61L31/04 ,  A61L27/54 ,  A61L27/20 ,  A61K8/73 ,  A61K8/67 ,  A61K8/42

摘要： An injectable hyaluronic acid composition including a hyaluronic acid; a local anesthetic selected from the group of amide and ester type local anesthetics or a combination thereof; and an ascorbic acid derivative in an amount which prevents or reduces the effect on the viscosity and/or elastic modulus G′ of the composition caused by the local anesthetic upon sterilization by heat. Further, the medical and non-medical, such as cosmetic, use of such a composition, and to a method of manufacturing such a composition.