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公开(公告)号：US20190211408A1
公开(公告)日：2019-07-11
申请号：US16306203
申请日：2017-06-02
申请人： Peter Lee , Raymond Huang , Kristin Ramos , Jules Chen , Michelle Tabb , Quest Diagnostics Investments LLC
发明人： Peter Lee , Raymond Huang , Kristin Ramos , Jules Chen , Michelle Tabb
IPC分类号： C12Q1/70
摘要： The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.
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公开(公告)号：US12077830B2
公开(公告)日：2024-09-03
申请号：US18097004
申请日：2023-01-13
发明人： Peter Lee , Raymond Huang , Kristin Ramos , Jules Chen , Michelle Tabb
CPC分类号： C12Q1/701 , A61P31/14 , C12N7/00 , C12Q1/68 , C12Q1/686 , C12Q1/70 , G01N33/56983 , A61K39/00 , C12N2770/16021 , C12Q2600/106 , C12Q2600/112 , G01N2333/08 , C12Q1/686 , C12Q2521/107 , C12Q1/70 , C12Q2521/107
摘要： The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.
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公开(公告)号：US10793924B2
公开(公告)日：2020-10-06
申请号：US16306203
申请日：2017-06-02
发明人： Peter Lee , Raymond Huang , Kristin Ramos , Jules Chen , Michelle Tabb
摘要： The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.
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公开(公告)号：US20230279513A1
公开(公告)日：2023-09-07
申请号：US18097004
申请日：2023-01-13
发明人： Peter Lee , Raymond Huang , Kristin Ramos , Jules Chen , Michelle Tabb
CPC分类号： C12Q1/701 , A61P31/14 , C12N7/00 , C12Q1/68 , C12Q1/70 , C12Q1/686 , G01N33/56983 , A61K39/00 , C12N2770/16021
摘要： The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.
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公开(公告)号：US11555223B2
公开(公告)日：2023-01-17
申请号：US17063078
申请日：2020-10-05
发明人： Peter Lee , Raymond Huang , Kristin Ramos , Jules Chen , Michelle Tabb
IPC分类号： A61K39/00 , A61K39/12 , A61K39/125 , C12N7/00 , C07K16/10 , C12Q1/70 , A61P31/14 , C12Q1/68 , C12Q1/686 , G01N33/569
摘要： The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.
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公开(公告)号：US20210095352A1
公开(公告)日：2021-04-01
申请号：US17063078
申请日：2020-10-05
发明人： Peter Lee , Raymond Huang , Kristin Ramos , Jules Chen , Michelle Tabb
摘要： The present disclosure provides methods and compositions for determining whether a patient exhibiting acute gastroenteritis will benefit from treatment with therapeutic agents that inhibit Norovirus genogroup I (GI) or Norovirus genogroup II (GII). The methods disclosed herein are based on detecting Norovirus genogroup I (GI) and Norovirus genogroup II (GII) in a stool sample without extracting viral nucleic acids from a clinical specimen prior to performing real-time reverse transcription PCR. Kits for use in practicing the methods are also provided.
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