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公开(公告)号：US20240342085A1
公开(公告)日：2024-10-17
申请号：US18580272
申请日：2022-07-17
发明人： Roey Jacob AMIR , Gadi SLOR , Shahar TEVET
CPC分类号： A61K9/1075 , A61K8/0291 , A61K8/8164 , A61K47/32
摘要： The present invention provides a stimuli-induced delivery system comprising self¬assembled amphiphilic tri-block copolymers in the form of micelles. The delivery system enables the release of a cargo from within the micelles following a transition to di-block copolymers micelles and subsequent activation by a protein to induce disassembly of the micelles.
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2.发明公开公开(公告)号：US20230303779A1
公开(公告)日：2023-09-28
申请号：US18190517
申请日：2023-03-27
发明人： Gili Hana BISKER , Roey Jacob AMIR , Verena WULF , Gadi SLOR , Parul RATHEE
IPC分类号： C08G83/00 , C01B32/159 , B82Y5/00 , G01N33/535 , G01N33/533
CPC分类号： C08G83/004 , C01B32/159 , B82Y5/00 , G01N33/535 , G01N33/533 , C01P2004/13
摘要： The present invention relates to highly modular amphiphilic polymer-dendron hybrids comprising hydrophobic dendrons conjugated to hydrophilic polymers that can be synthesized with a high degree of structural freedom, for suspending SWCNTs in aqueous solution. Utilizing the susceptibility of the polymer-dendrons towards enzymatic degradation, the present invention provides methods of detecting the presence of an enzyme in a sample as well as methods of monitoring of enzymatic activity by changes in the SWCNT fluorescent signal.
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