公开(公告)号：US20240285723A1

公开(公告)日：2024-08-29

申请号：US18573517

申请日：2022-06-22

Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.

Inventor： Yankel GABET ,  Josef MOGRABI

IPC: A61K38/08 ,  A61K31/015 ,  A61K31/497 ,  A61K31/566 ,  A61K31/573 ,  A61P31/00 ,  A61P37/06

CPC classification number: A61K38/08 ,  A61K31/015 ,  A61K31/497 ,  A61K31/566 ,  A61K31/573 ,  A61P31/00 ,  A61P37/06

Abstract: Pharmaceutical compositions are provided, comprising at least one selective CB2 receptor agonist and at least one steroid. The provided compositions are effective in treating inflammation and/or pathogen related inflammation and associated complications thereof. Also provided are methods for treating a subject infected with a pathogen as well as inflammation, using said compositions.

公开(公告)号：US20240009177A1

公开(公告)日：2024-01-11

申请号：US18245970

申请日：2021-09-19

Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.

Inventor： Dor ZAGURI ,  Topaz KREISER-SHEM-TOV ,  Ehud GAZIT ,  Daniel SEGAL ,  Josef MOGRABI ,  Eran BACHARACH

IPC: A61K31/4375 ,  A61K31/352 ,  A61K33/34 ,  A61K31/315 ,  A61P31/16

CPC classification number: A61K31/4375 ,  A61K31/352 ,  A61K33/34 ,  A61K31/315 ,  A61P31/16

Abstract: Combination compositions exhibiting anti-viral activities are provided, which are based on unique combinations of polyphenol zinc ionophores. Exemplary compositions comprise combinations of flavonoid zinc ionophores selected from EGCG, quercetin and taxifolin, preferably further comprising a zinc compound and a copper compound. The compositions preferably contain additional ingredients to further enhance the anti-viral effect of the composition and/or to provide additional benefits.