公开(公告)号：US20130345276A1

公开(公告)日：2013-12-26

申请号：US13886053

申请日：2013-05-02

申请人： REATA PHARMACEUTICALS, INC. ,  TRUSTEES OF DARTMOUTH COLLEGE

发明人： Michael B. SPORN ,  Karen T. LIBY ,  Gordon W. GRIBBLE ,  Tadashi HONDA ,  Robert M. KRAL ,  Colin J. MEYER

IPC分类号： A61K31/4174 ,  A61K31/277

CPC分类号： A61K31/4174 ,  A61K31/275 ,  A61K31/277 ,  A61K31/4164 ,  A61K2300/00

摘要： The present invention concerns methods for treating and preventing renal/kidney disease, insulin resistance/diabetes, fatty liver disease, and/or endothelial dysfunction/cardiovascular disease using synthetic triterpenoids, optionally in combination with a second treatment or prophylaxis.