公开(公告)号：US11883528B2

公开(公告)日：2024-01-30

申请号：US17893612

申请日：2022-08-23

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： David H. Ingbar ,  Timothy P. Rich ,  Robert J. Schumacher ,  Jianxun Lei ,  Maneesh Bhargava

IPC: A61K9/00 ,  A61K31/198 ,  A61P11/00

CPC classification number: A61K9/0078 ,  A61K31/198 ,  A61P11/00

Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to a pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.

公开(公告)号：US20240350406A1

公开(公告)日：2024-10-24

申请号：US18539744

申请日：2023-12-14

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： David H. Ingbar ,  Timothy P. Rich ,  Robert J. Schumacher ,  Jianxun Lei ,  Maneesh Bhargava

IPC: A61K9/00 ,  A61K31/198 ,  A61P11/00

CPC classification number: A61K9/0078 ,  A61K31/198 ,  A61P11/00

Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to a pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.

公开(公告)号：US20230050861A1

公开(公告)日：2023-02-16

申请号：US17893612

申请日：2022-08-23

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： David H. Ingbar ,  Timothy P. Rich ,  Robert J. Schumacher ,  Jianxun Lei ,  Maneesh Bhargava

IPC: A61K9/00 ,  A61P11/00 ,  A61K31/198

Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to a pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.

公开(公告)号：US11458094B2

公开(公告)日：2022-10-04

申请号：US16965095

申请日：2019-01-31

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： David H. Ingbar ,  Timothy P. Rich ,  Robert J. Schumacher ,  Jianxun Lei ,  Maneesh Bhargava

IPC: A61K9/00 ,  A61K31/198 ,  A61P11/00

Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.

公开(公告)号：US20210113462A1

公开(公告)日：2021-04-22

申请号：US16965095

申请日：2019-01-31

Applicant: REGENTS OF THE UNIVERSITY OF MINNESOTA

Inventor： David H. Ingbar ,  Timothy P. Rich ,  Robert J. Schumacher ,  Jianxun Lei ,  Maneesh Bhargava

IPC: A61K9/00 ,  A61K31/198 ,  A61P11/00

Abstract: A pharmaceutical composition for administering directly to the pulmonary tract of a subject includes a salt of triiodothyronine and a pharmaceutically acceptable buffer, adjusted to pH of 5.5-8.5. The composition can be administered prophylactically or therapeutically to a subject to treat lung inflammation or pulmonary edema.