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公开(公告)号：US11004552B2
公开(公告)日：2021-05-11
申请号：US15621798
申请日：2017-06-13
Applicant: ROCA MEDICAL LTD.
Inventor： James Strader , Jovan Hutton Pulitzer
Abstract: A method for creating a multi-antigen patch, comprising providing one or more transdermal patch sheets having a plurality of single dose transdermal patches residing thereon, wherein each one of the plurality of single dose transdermal patches includes an antigen at a particular dilution level disposed within a carrier, removing one or more of the plurality of single dose transdermal patches from the one or more transdermal patch sheets, adhering the one or more of the plurality of single dose transdermal patches to a backing, wherein the backing allows for multiple single dose transdermal patches to be adjacently adhered thereon, and covering the plurality of transdermal patches adhered to the backing with a peelable release liner.
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公开(公告)号：US20200078612A1
公开(公告)日：2020-03-12
申请号：US16530409
申请日：2019-08-02
Applicant: ROCA Medical Ltd.
Inventor： James Strader , Jovan Hutton Pulitzer
Abstract: A method for delivering an immunomodulator to a patient includes providing a bottle of concentrated immunomodulator extract; progressively diluting the antigen extract in sterile bottles; selecting a prescribed amount from a desired one of the dilution bottles; providing a viscous encapsulation material that is able to introduce antigens contained therein through the skin of a patient; introducing one or more doses of the selected prescribed amount of diluted immunomodulator into the viscous encapsulation material; disposing a prescribed amount of viscous encapsulation material containing the introduced diluted immunomodulator therein within a container that is able to dispense such viscous encapsulation material containing the introduced diluted immunomodulator; dispensing from the container the amount of viscous encapsulation material containing the diluted immunomodulator in an amount equal to a single dose; and applying the dispensed viscous encapsulation material containing the introduced diluted immunomodulator to the skin by the patient or a medical professional.
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公开(公告)号：US12004864B2
公开(公告)日：2024-06-11
申请号：US16827785
申请日：2020-03-24
Applicant: ROCA MEDICAL LTD.
Inventor： James Strader , Jovan Hutton Pulitzer
IPC: A61B5/00
CPC classification number: A61B5/411
Abstract: A prick test kit comprises a bottom tray containing a plurality of wells disposed in an array, wherein each of the wells contains a vial of a small amount of a specific well associated antigen, with each well and associated vial having a different antigen disposed therein, each of the vials having a rubber cap disposed thereon that is sterile and able to be pricked by a needle such that the small amount of antigen can be removed therefrom. A penetrating plate is disposed above the wells and having on the lower surface thereof diametrically opposite from the vials in the wells a plurality of piercing needles, one associated with each of the wells and directed downward there to but not touching any of the files. A separating plate is disposed between the bottom tray and the penetrating plate. A sterile covering is provided for containing the entire assembly.
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公开(公告)号：US10548974B2
公开(公告)日：2020-02-04
申请号：US15222790
申请日：2016-07-28
Applicant: ROCA MEDICAL LTD.
Inventor： James Strader , Jovan Hutton Pulitzer
Abstract: A therapeutic treatment kit includes a container for holding a plurality of compartmentalized therapeutic dispensers. Each of the therapeutic dispensers includes a plurality of vials of antigens, and a plurality of containers of supplements disposed in compartments, each of the compartments labeled with the name of the supplement. A compartment is also provided for containing applicators or the antigens, such that an individual can extract the antigen from the vial in a single dose; and para instructions associated with a therapeutic program for utilizing the vials of antigens and the supplements in accordance with a therapeutic program that is predefined. The construction of the kit, including the dosages of the antigen, the types of antigens and the supplements all associated with a particular therapeutic program.
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公开(公告)号：US20150290129A1
公开(公告)日：2015-10-15
申请号：US14685573
申请日：2015-04-13
Applicant: ROCA Medical Ltd.
Inventor： James Strader , Jovan Hutton Pulitzer
CPC classification number: A61K9/06 , A61K9/0014 , A61K39/00 , A61K39/35 , A61K2039/541 , A61K2039/545
Abstract: A method for delivering an immunomodulator to a patient includes providing a bottle of concentrated immunomodulator extract; progressively diluting the antigen extract in sterile bottles; selecting a prescribed amount from a desired one of the dilution bottles; providing a viscous encapsulation material that is able to introduce antigens contained therein through the skin of a patient; introducing one or more doses of the selected prescribed amount of diluted immunomodulator into the viscous encapsulation material; disposing a prescribed amount of viscous encapsulation material containing the introduced diluted immunomodulator therein within a container that is able to dispense such viscous encapsulation material containing the introduced diluted immunomodulator; dispensing from the container the amount of viscous encapsulation material containing the diluted immunomodulator in an amount equal to a single dose; and applying the dispensed viscous encapsulation material containing the introduced diluted immunomodulator to the skin by the patient or a medical professional.
Abstract translation: 向患者递送免疫调节剂的方法包括提供一瓶浓缩的免疫调节剂提取物; 逐渐稀释无菌瓶中的抗原提取物; 从期望的一个稀释瓶中选择规定量; 提供能够通过患者皮肤将包含在其中的抗原引入的粘性包封材料; 将一个或多个剂量的选择的规定量的稀释的免疫调节剂引入粘稠的包封材料中; 将含有引入的稀释免疫调节剂的规定量的粘稠包封材料置于容器内，该容器能够分配含有引入的稀释免疫调节剂的这种粘性包封材料; 从容器中分配含有等于单次剂量的稀释免疫调节剂的粘稠包封材料的量; 以及由患者或医疗专业人员将含有引入的稀释免疫调节剂的分散的粘稠包封材料施用于皮肤。
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Patent Agency Ranking
公开(公告)号：US11154237B2
公开(公告)日：2021-10-26
申请号：US16653399
申请日：2019-10-15
Applicant: ROCA MEDICAL LTD.
Inventor： James Strader , Jovan Hutton Pulitzer
Abstract: A method for administering tests using a regional antigen testing kit is provided. The method comprises providing the regional antigen testing kit, extracting a predetermined amount of concentrated antigen from one of a plurality of concentrated antigens, dispensing the predetermined amount of concentrated antigen into a corresponding one of a plurality of wells, as indicated by visual indicia, repeating the extracting and dispensing steps until a desired number of the plurality of wells contain concentrated antigen, providing a prick tester having a plurality of needles extending thereon, aligning the plurality of needles of the prick tester with the plurality of wells, inserting each of the plurality of needles of the prick tester into one of the plurality of wells, and applying the plurality of needles of the prick tester to the skin of a patient to elicit a potential response.
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公开(公告)号：US10813992B2
公开(公告)日：2020-10-27
申请号：US16531576
申请日：2019-08-05
Applicant: ROCA MEDICAL LTD.
Inventor： James Strader , Jovan Hutton Pulitzer
Abstract: A method for delivering allergens to a pharmacist in a pre-diluted kit form, comprising providing a bulk container of base concentrate antigen containing at least one antigen at a predetermined concentrated level, creating a sequential and more diluted sequence of antigens, providing a plurality of end-use sealable containers that can receive a finite end amount of diluted antigens, dispensing from each of sequential bulk containers a finite end amount of diluted antigens into one of the plurality of end-use sealable containers, wherein the end-use seal containers filled from each of the sequential bulk containers comprises a group of end-use sealable containers associated with each of the sequential bulk containers, sealing each of the end-use containers after diluted antigens are disposed therein, and disposing a select number of the sealed end-use sealable containers from each of the groups of end-use sealable containers into a container comprising a kit.
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公开(公告)号：US10595768B2
公开(公告)日：2020-03-24
申请号：US15222709
申请日：2016-07-28
Applicant: ROCA MEDICAL LTD.
Inventor： James Strader , Jovan Hutton Pulitzer
IPC: A61B5/00
Abstract: A prick test kit comprises a bottom tray containing a plurality of wells disposed in an array, wherein each of the wells contains a vial of a small amount of a specific well associated antigen, with each well and associated vial having a different antigen disposed therein, each of the vials having a rubber cap disposed thereon that is sterile and able to be pricked by a needle such that the small amount of antigen can be removed therefrom. A penetrating plate is disposed above the wells and having on the lower surface thereof diametrically opposite from the vials in the wells a plurality of piercing needles, one associated with each of the wells and directed downward there to but not touching any of the files. A separating plate is disposed between the bottom tray and the penetrating plate. A sterile covering is provided for containing the entire assembly.
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公开(公告)号：US10441209B2
公开(公告)日：2019-10-15
申请号：US15425863
申请日：2017-02-06
Applicant: ROCA MEDICAL LTD.
Inventor： James Strader , Jovan Hutton Pulitzer
Abstract: A method for administering tests using a regional antigen testing kit is provided. The method comprises providing the regional antigen testing kit, extracting a predetermined amount of concentrated antigen from one of a plurality of concentrated antigens, dispensing the predetermined amount of concentrated antigen into a corresponding one of a plurality of wells, as indicated by visual indicia, repeating the extracting and dispensing steps until a desired number of the plurality of wells contain concentrated antigen, providing a prick tester having a plurality of needles extending thereon, aligning the plurality of needles of the prick tester with the plurality of wells, inserting each of the plurality of needles of the prick tester into one of the plurality of wells, and applying the plurality of needles of the prick tester to the skin of a patient to elicit a potential response.
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公开(公告)号：US11369576B2
公开(公告)日：2022-06-28
申请号：US15865001
申请日：2018-01-08
Applicant: ROCA MEDICAL LTD.
Inventor： James Strader , Jovan Hutton Pulitzer
IPC: A61K9/70 , A61K39/35 , A61K31/4188 , A61K39/00 , A61P37/02 , A61K31/437 , A61K9/06 , A61K45/06 , A61P17/00 , A61K39/36 , A61P37/08 , A61K47/12 , A61K47/10
Abstract: A method for creating a consolidated compound for delivering an immunomodulatory and imiquimod to a patient, comprising diluting immunomodulator extract to a desired dilution by transferring a desired quantity of the concentrated immunomodulator to an associated sterile container, the associated sterile container having a defined volume of diluted immunomodulator after dilution thereof, providing a viscous encapsulation material, selecting a prescribed amount of concentrated immunomodulator, the prescribed amount defined as that amount of the diluted immunomodulator extract required to provide a number of doses equal to the number of dispensable increments from the container containing the viscous encapsulation material, introducing the selected amount of each of the diluted immunomodulator extract into the viscous encapsulation material, introducing an amount of imiquimod into the viscous encapsulation material, and mixing the introduced amount of each of the diluted immunomodulator extracts and the introduced amount of imiquimod with the viscous encapsulating material.
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