Multicore fiber imaging
    1.
    发明授权

    公开(公告)号:US11684240B2

    公开(公告)日:2023-06-27

    申请号:US16965513

    申请日:2019-01-25

    Inventor: Antony Orth

    Abstract: The invention relates to multicore fiber imaging, such as used in endoscopy. Methods are described for processing images captured with such systems to achieve an improved depth of field image or extract 3D information concerning the images, without requiring the addition of additional optical components. One method for generating an image from light received by an imager via a multiplicity of waveguides includes receiving a digital image containing a plurality of pixels, the digital image including a plurality of regions within it wherein each of said regions corresponds to a waveguide core. Each region includes a plurality of pixels, and a first subset of pixels within each region is defined which at least partly correlates with light having been received at a corresponding core in a first spatial arrangement, the subset including less than all of the pixels within a region. A first image is generated from the first subset of pixels from said regions, combined to form an image over the whole waveguide array. The first spatial arrangement may correspond to a measure of angular dimension of the incident light for that region. In addition to increased depth of field, the modified images provided by the invention allow 3D visualisation of objects, eg. using stereographs or depth mapping techniques.

    A METHOD FOR DISTINGUISHING BETWEEN MORE THAN ONE FLUORESCENT SPECIES PRESENT IN A SAMPLE

    公开(公告)号:US20210334513A1

    公开(公告)日:2021-10-28

    申请号:US16322742

    申请日:2017-08-03

    Inventor: Antony Orth

    Abstract: Methods and systems are provided for distinguishing between more than one fluorescent species present in a sample in fluorescence microscopy. The method involves illuminating the sample with at least one light source. More than two images of the illuminated sample are recorded over a period of time, each image comprising a plurality of pixels, wherein each pixel corresponds to a location in the sample and records a degree of fluorescence at the location in the sample at a particular point in time. A photostability characteristic of the degree of fluorescence at each pixel over the period of time over which the more than two images were recorded is determined and used to distinguish between the more than one fluorescent species present in the sample.

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