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公开(公告)号：US20120308517A1
公开(公告)日：2012-12-06
申请号：US13577835
申请日：2011-02-07
申请人： Rafael Aldabe Arregui , Iranzu Gonzalez De La Tajada , Maria Esther Larrea Leoz , Jesus Maria Prieto Valtuena
发明人： Rafael Aldabe Arregui , Iranzu Gonzalez De La Tajada , Maria Esther Larrea Leoz , Jesus Maria Prieto Valtuena
CPC分类号： A61K38/204 , A61K38/21 , A61K2300/00
摘要： The present invention relates to the use of compositions comprising a type III interferon and oncostatin M and to the use of said compositions for the treatment and prevention of infectious and neoplastic diseases.
摘要翻译： 本发明涉及包含III型干扰素和制瘤素M的组合物的用途以及所述组合物用于治疗和预防感染性和肿瘤性疾病的用途。
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公开(公告)号：US20120237535A1
公开(公告)日：2012-09-20
申请号：US13394610
申请日：2010-09-10
申请人： Pedro Berraondo-Lopez , Juan Jose Lasarte Sagastibelza , Christina Mansilla Puerta , Jesus Maria Prieto Valtuena , Pablo Sarobe Ugarriza
发明人： Pedro Berraondo-Lopez , Juan Jose Lasarte Sagastibelza , Christina Mansilla Puerta , Jesus Maria Prieto Valtuena , Pablo Sarobe Ugarriza
IPC分类号： A61K39/12 , C12N15/62 , A61P31/20 , A61P35/00 , C12N5/0784 , C12N15/63 , C12N1/21 , C12N1/19 , C12N5/10 , C07K19/00 , A61P37/04
CPC分类号： A61K47/48292 , A61K35/12 , A61K38/00 , A61K39/12 , A61K47/6435 , A61K47/646 , A61K2039/5154 , A61K2039/55561 , A61K2039/585 , A61K2039/6031 , C07K14/005 , C07K14/78 , C07K2319/75 , C12N2710/20022 , C12N2710/20032 , C12N2710/20034
摘要： The invention relates to immunogenic conjugates comprising an immunogenic region of human papilloma virus E7 protein and the fibronectin EDA region, as well to compositions comprising said conjugates and to dendritic cells obtained by stimulation with said conjugates and compositions. Moreover, the invention relates to methods for the treatment of diseases caused by the human papilloma virus (HPV) using said conjugates, compositions and dendritic cells.
摘要翻译： 本发明涉及包含人乳头状瘤病毒E7蛋白和纤连蛋白EDA区域的免疫原性区域的免疫原性缀合物，以及包含所述缀合物的组合物和通过用所述缀合物和组合物刺激获得的树突状细胞。 此外，本发明涉及使用所述缀合物，组合物和树突状细胞治疗由人乳头瘤病毒（HPV）引起的疾病的方法。
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3.发明申请公开(公告)号：US20110293562A1
公开(公告)日：2011-12-01
申请号：US13201431
申请日：2010-02-10
CPC分类号： A61K38/204 , A61K38/28
摘要： The invention is related to the use of cardiotrophin-1 (CT-1) for the treatment of obesity and associated disorders: hyperglycaemias, insulin resistance, development of type 2 diabetes and dyslipemias and given its anorexigenic role, fat oxidation stimulant, hypoglycaemic, sensitizing agent of the action of insulin on a skeletal muscle level and inhibitor of the intestinal transport of glucose by enterocytes.
摘要翻译： 本发明涉及心肌营养因子-1（CT-1）用于治疗肥胖症和相关疾病的用途：高血糖症，胰岛素抵抗，2型糖尿病和血脂异常的发展并给予其厌食症作用，脂肪氧化兴奋剂，低血糖，致敏 胰岛素对骨骼肌水平的作用的药剂和由肠细胞肠葡萄糖转运的抑制剂。
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