公开(公告)号：US20090270712A1

公开(公告)日：2009-10-29

申请号：US12423228

申请日：2009-04-14

申请人： Raghu Raghavan ,  Martin Brady ,  Maria Inmaculada Rodriguez-Ponce

发明人： Raghu Raghavan ,  Martin Brady ,  Maria Inmaculada Rodriguez-Ponce

IPC分类号： A61M37/00 ,  A61B6/00 ,  A61B19/00

CPC分类号： A61M5/1723 ,  A61B5/055 ,  A61B34/10 ,  A61B90/36 ,  A61M2005/14292 ,  A61M2210/0693 ,  G01R33/281 ,  G01R33/5608

摘要： A method for identifying target regions in a tissue for local drug delivery, wherein functional and/or structural anatomical data such as edema and/or resection cavity is captured by an imaging system, and wherein the anatomical data is evaluated by segmentation techniques such as region-growing-based methods with computer assistance to determine a margin around a resection cavity and/or the volume of edema, the margin and/or the volume of edema being the target tissue for local drug delivery.

摘要翻译： 一种用于识别用于局部药物递送的组织中的目标区域的方法，其中由成像系统捕获功能和/或结构解剖学数据，例如水肿和/或切除腔，并且其中所述解剖数据通过分割技术（例如区域 计算机辅助的基于成长的方法来确定切除腔周围的边缘和/或水肿体积，水肿的边缘和/或体积是用于局部药物递送的目标组织。

公开(公告)号：US10124114B2

公开(公告)日：2018-11-13

申请号：US12423228

申请日：2009-04-14

申请人： Raghu Raghavan ,  Martin Brady ,  Maria Inmaculada Rodriguez-Ponce

发明人： Raghu Raghavan ,  Martin Brady ,  Maria Inmaculada Rodriguez-Ponce

IPC分类号： A61B5/05 ,  A61M5/172 ,  A61B90/00 ,  A61B5/055 ,  A61M5/142 ,  G01R33/28 ,  G01R33/56 ,  A61B34/10

摘要： A method for identifying target regions in a tissue for local drug delivery, where functional and/or structural anatomical data such as edema and/or resection cavity is captured by an imaging system, and where the anatomical data is evaluated by segmentation techniques such as region-growing-based methods with computer assistance to determine a margin around a resection cavity and/or the volume of edema, the margin and/or the volume of edema being the target tissue for local drug delivery.

公开(公告)号：US20130035921A1

公开(公告)日：2013-02-07

申请号：US13575637

申请日：2010-01-28

申请人： Maria Inmaculada Rodriguez-Ponce ,  Stephan Mittermeyer

发明人： Maria Inmaculada Rodriguez-Ponce ,  Stephan Mittermeyer

IPC分类号： G06G7/56

CPC分类号： A61B5/417 ,  A61B5/015 ,  A61B5/055 ,  A61N1/403 ,  G01R33/4804 ,  G01R33/56366 ,  G09B23/28

摘要： The invention relates a method and an apparatus of predicting or planning a temperature distribution (52) in a body. The method comprises the steps of : a) obtaining a model of the body (50) related to a temperature transport mechanism or temperature distribution (52) in the body; b) simulating an application of heat to at least a part of the body such as targeted tissue; c) determining and/or predicting the temperature (52) or heat distribution in at least a part of the body using the model of the body (50).

摘要翻译： 本发明涉及一种预测或规划身体温度分布（52）的方法和装置。 该方法包括以下步骤：a）获得与身体温度传递机构或温度分布（52）相关的身体（50）的模型; b）模拟对身体的至少一部分（例如靶组织）施加热量; c）使用身体（50）的模型来确定和/或预测身体的至少一部分中的温度（52）或热分布。