公开(公告)号：US5111145A

公开(公告)日：1992-05-05

申请号：US663076

申请日：1991-02-28

Applicant: Raimo E. Sepponen

Inventor： Raimo E. Sepponen

IPC: G01R33/44 ,  A61B5/055 ,  A61B10/00 ,  G01N24/12 ,  G01R33/48 ,  G01R33/62

CPC classification number: G01R33/62

Abstract: The invention relates to a method and apparatus for applying dynamic nuclear polarization and magnetic imaging to studying an object. As the saturation of an electron spin system required by dynamic nuclear polarization is proceeding, the intensity of a polarizing magnetic field over the object is different from that of a polarizing magnetic field lying over the object during the detection of an NMR signal. The apparatus is provided with means for changing the intensity of a polarizing magnetic field in a manner such that the difference between magnetic field intensities is achieved.

Abstract translation: 本发明涉及一种将动态核偏振和磁成像应用于研究物体的方法和装置。 随着动态核极化所需的电子自旋系统的饱和状态的进行，在检测NMR信号期间，物体上的偏振磁场的强度与位于物体上的偏振磁场的强度不同。 该装置设置有以使得实现磁场强度之间的差异的方式改变偏振磁场的强度的装置。

公开(公告)号：US5498962A

公开(公告)日：1996-03-12

申请号：US209427

申请日：1994-03-10

Applicant: Raimo E. Sepponen

Inventor： Raimo E. Sepponen

IPC: G01R33/483 ,  G01R33/563 ,  G01V3/14

CPC classification number: G01R33/4833 ,  G01R33/56308

Abstract: An SLP pulse is applied to an object to be imaged preceding one or more excitation pulses (a.sup.o or a) of a known magnetic resonance imaging technique. The SLP pulse tilts the nuclear magnetization away from the direction of B.sub.o, locks the magnetization with the rotating magnetic component and returns the magnetization back to the direction of B.sub.o. The known magnetic resonance imaging technique used with the SLP pulse includes applying at least one excitation pulse to generate transverse magnetization in the object. The excitation pulse causes the angle between the nuclear magnetization and B.sub.o to be less than 90.degree..

Abstract translation: 在已知的磁共振成像技术的一个或多个激励脉冲（ao或a）之前，将SLP脉冲施加到要成像的对象。 SLP脉冲使核磁化远离Bo的方向，将磁化与磁性分量锁定，并将磁化返回到Bo的方向。 与SLP脉冲一起使用的已知磁共振成像技术包括施加至少一个激励脉冲以在物体中产生横向磁化。 励磁脉冲使核磁化和Bo之间的角度小于90°。

公开(公告)号：US4641659A

公开(公告)日：1987-02-10

申请号：US369804

申请日：1982-04-19

Applicant: Raimo E. Sepponen

Inventor： Raimo E. Sepponen

IPC: A61B10/00 ,  A61B5/05 ,  G01S7/04 ,  G01S13/89

CPC classification number: A61B5/4312 ,  A61B5/05 ,  A61B5/0507 ,  G01S13/89 ,  G01S7/04

Abstract: Microwave apparatus for diagnosis of cancer of the breast includes a microwave transmitter and a microwave antenna for directing a microwave signal to the breast under examination, and a microwave receiver having amplitude and phase shift detectors for receiving of reflected microwave signals. A processor is connected to the receiver for processing the amplitude and phase information to detect and locate cancer in the breast. A matching plate having a dielectric constant substantially the same as normal breast tissue is located between and in engagement with the breast and antenna. The antenna engages and sweeps over the plane surface of the matching plate to eliminate any air gap in the transmission path. A display unit is connected to the processor to create a microwave image of cancer growth, if any.

Abstract translation: 用于诊断乳腺癌的微波装置包括微波发射器和用于将微波信号引导到被检查的乳房的微波天线，以及具有用于接收反射的微波信号的振幅和相移检测器的微波接收器。 处理器连接到接收器，用于处理幅度和相位信息以检测和定位乳房中的癌症。 具有与正常乳房组织基本相同的介电常数的匹配板位于乳房和天线之间并与乳房和天线接合。 天线接合并扫过匹配板的平面，以消除传输路径中的任何气隙。 显示单元连接到处理器以产生癌症生长的微波图像（如果有的话）。

公开(公告)号：US5592084A

公开(公告)日：1997-01-07

申请号：US158990

申请日：1993-11-30

Applicant: Raimo E. Sepponen

Inventor： Raimo E. Sepponen

IPC: G01R33/563 ,  G01V3/14 ,  G01V3/00 ,  A61B5/0265 ,  A61B5/055

CPC classification number: G01V3/14 ,  G01R33/563

Abstract: The invention relates to a method for examination of motion of material employing magnetic resonance imaging methods. A magnetic field, which is referred as an auxiliary field is applied over the first area of the object, this auxiliary field is arranged to get smaller as one moves from the first area to the second area, referred as the area to be examined. Partially simultaneously with the auxiliary field a radio frequency pulse, AHP-pulse, is applied on the object, the frequency of the AHP-pulse is the Larmor-frequency corresponding to the strength of the magnetic field in the area to be examined. The length of the AHP-pulse corresponds to the time, which is required for the material to move from the first area to the area to be examined.

Abstract translation: 本发明涉及使用磁共振成像方法检查材料运动的方法。 称为辅助场的磁场被施加在物体的第一区域上，该辅助场被布置为随着从第一区域移动到第二区域（被称为被检查区域）而变小。 与辅助场部分同时，物体上施加射频脉冲AHP脉冲，AHP脉冲的频率是对应于待检测区域的磁场强度的拉莫尔频率。 AHP脉冲的长度对应于材料从第一个区域移动到待检测区域所需的时间。

公开(公告)号：US5146924A

公开(公告)日：1992-09-15

申请号：US400461

申请日：1989-08-29

Applicant: Raimo E. Sepponen

Inventor： Raimo E. Sepponen

IPC: A61B5/055 ,  A61B8/08 ,  G01R33/36 ,  G01R33/62

CPC classification number: G01R33/4814 ,  A61B5/0035 ,  A61B5/055 ,  A61B8/08 ,  G01R33/62 ,  G01R33/3621 ,  G01R33/385 ,  G01R33/3875

Abstract: An apparatus for the examination of an object, such as a human body, by means of ultrasound and NMR methods in such a manner that both examination methods are adapted to be effected substantially simultaneously and on the same target area. The apparatus is provided with a device for radiating the magnetization of an electron spin system in the said target area in order to achieve a dynamic nuclear polarization and to amplify an NMR signal through a so-called Overhauser-phenomenon.

Abstract translation: 一种用于通过超声和​​NMR方法检查物体（例如人体）的装置，使得两种检查方法适于基本上同时进行并且在相同的目标区域上进行。 该装置设置有用于在所述目标区域中辐射电子自旋系统的磁化以便实现动态核极化并通过所谓的Overhauser现象放大NMR信号的装置。

公开(公告)号：US4374360A

公开(公告)日：1983-02-15

申请号：US154595

申请日：1980-05-29

Applicant: Raimo E. Sepponen

Inventor： Raimo E. Sepponen

IPC: A61B5/055 ,  G01R33/48 ,  G01N27/00

CPC classification number: G01R33/445 ,  A61B5/055

Abstract: A nuclear magnetic resonance diagnosis apparatus includes first members which generate an inhomogeneous magnetic field within which the object is placed, and second members which includes a member which is rotated mechanically within the field. A mechanical motion of the member continuously modifies the strength of the inhomogeneous magnetic field except for a sampling line on the axis of rotation. The sampling line is located to pass through the sampling point. The field strength on the sampling line is at a constant prescribed intensity. It is advantageous in actual practice to carry out the apparatus of the invention. The first members include a solenoid magnet of a supra-conductor with a central axis coinciding with the sampling line. The second members include a rotatably carried permanent magnet having a central axis of rotation on the central axis of the solenoid magnet. The magnetic field strength of predetermined magnitude or intensity occurs only at one point which is a given distance from the central point of the solenoid on the solenoid's central axis.

Abstract translation: 核磁共振诊断装置包括产生放置物体的非均匀磁场的第一构件和包括在场内机械旋转的构件的第二构件。 该构件的机械运动连续地改变除旋转轴线上的取样线之外的不均匀磁场的强度。 采样线位于通过采样点。 取样线上的场强处于恒定的规定强度。 在实际实践中实施本发明的装置是有利的。 第一构件包括具有与取样线重合的中心轴的超导体的螺线管磁体。 第二构件包括在螺线管磁体的中心轴上具有中心旋转轴线的可旋转地承载的永磁体。 预定幅度或强度的磁场强度仅发生在与螺线管的中心轴上的螺线管的中心点给定距离的一个点处。