专利检索 ap:("Rainer Figge" OR "Gwenaelle Bestel-Corre" OR "Celine Raynaud" OR "Philippe Soucaille") AND inv:"Celine Raynaud" 第 1 页

1.

发明申请
Process for the Preparation of a Aspartate and Derived Amino Acids Like Lysine, Threonine, Isoleucine, Methionine, or Homoserine Employing Microorganism with Enhanced Isocitrate Lyase and/or Malate Synthase Expression 审中-公开
标题翻译：用赖氨酸，苏氨酸，异亮氨酸，甲硫氨酸或高丝氨酸制备天冬氨酸和衍生的氨基酸的方法，其使用具有增强的异柠檬酸裂解酶和/或苹果酸合酶表达的微生物

公开(公告)号：US20080233617A1

公开(公告)日：2008-09-25

申请号：US11997732

申请日：2006-08-11

申请人： Rainer Figge , Gwenaelle Bestel-Corre , Celine Raynaud , Philippe Soucaille

发明人： Rainer Figge , Gwenaelle Bestel-Corre , Celine Raynaud , Philippe Soucaille

IPC分类号： C12P13/20

CPC分类号： C12P13/20 , C12P13/06 , C12P13/08 , C12P13/12

摘要： The present invention relates to increasing the product of aspartate or aspartate-derived metabolites by boosting the activity of the glyoxylate shunt. This is accomplished by increasing the activity of glyoxylate shunt specific enzymes and decreasing the activity of reactions consuming glyoxylate and its precursors.

摘要翻译： 本发明涉及通过提高乙醛酸分流的活性来增加天冬氨酸或天冬氨酸衍生的代谢产物的产物。这通过增加乙醛酸分流特异性酶的活性并降低消耗乙醛酸及其前体的反应的活性来实现。

2.

发明申请
Recombinant enzyme with altered feedback sensitivity 有权
标题翻译：具有改变的反馈灵敏度的重组酶

公开(公告)号：US20090029424A1

公开(公告)日：2009-01-29

申请号：US11579907

申请日：2005-05-12

申请人： Gwenaelle Bestel-Corre , Michel Chateau , Rainer Figge , Celine Raynaud , Philippe Soucaille

发明人： Gwenaelle Bestel-Corre , Michel Chateau , Rainer Figge , Celine Raynaud , Philippe Soucaille

IPC分类号： C12P13/12 , C12N9/00 , C12N15/52 , C12N1/21

CPC分类号： C12N9/1029

摘要： The present invention relates to the use of recombinant homoserine transsuccinylase enzymes with altered feedback sensitivity (MetA*) and possibly recombinant S-adenosyl methionine synthetase enzymes with reduced activity (MetK*) for the production of methionine, its precursors or derivatives thereof.

摘要翻译： 本发明涉及具有改变的反馈敏感性（MetA *）的重组高丝氨酸跨琥珀酰酶和可能具有降低的活性（MetK *）的重组S-腺苷甲硫氨酸合成酶用于产生甲硫氨酸，其前体或衍生物的用途。

3.

发明申请
Methods for Producing Methionine by Culturing a Microorganism Modified to Enhance Production of Cysteine 有权
标题翻译：通过培养修饰增加半胱氨酸生产的微生物生产甲硫氨酸的方法

公开(公告)号：US20080311632A1

公开(公告)日：2008-12-18

申请号：US12159846

申请日：2006-01-04

申请人： Rainer Figge , Fabien Lux , Celine Raynaud , Michel Chateau , Philippe Soucaille

发明人： Rainer Figge , Fabien Lux , Celine Raynaud , Michel Chateau , Philippe Soucaille

IPC分类号： C12P13/12 , C12N1/20

CPC分类号： C12P13/12 , C12P13/06

摘要： A method of producing methionine, derivatives or precursors thereof comprising culturing a microorganism modified to enhance production of cysteine in a culture medium comprising a source of carbon and a source of sulfur and recovering methionine from the culture medium. A microorganism for fermentative production of methionine or its derivatives in which production of methionine or derivatives thereof, wherein the microorganism enhances production of cysteine.

摘要翻译： 一种产生甲硫氨酸，其衍生物或前体的方法，包括培养在包含碳源和硫源并从培养基中回收甲硫氨酸的培养基中修饰以增强半胱氨酸生产的微生物。用于发酵生产甲硫氨酸或其衍生物的微生物，其中所述微生物增加半胱氨酸的产生，其中产生甲硫氨酸或其衍生物。