公开(公告)号：US20080045663A1

公开(公告)日：2008-02-21

申请号：US11810988

申请日：2007-06-07

申请人： Rainer Kolb ,  Agaplos Agapiou ,  James Farley ,  Eric Markel ,  Bruce Savatsky ,  Christopher Davey ,  Richard Pannell

发明人： Rainer Kolb ,  Agaplos Agapiou ,  James Farley ,  Eric Markel ,  Bruce Savatsky ,  Christopher Davey ,  Richard Pannell

IPC分类号： C08F10/02 ,  C08L23/06

CPC分类号： C08F210/16 ,  Y10S526/901 ,  Y10S526/943 ,  C08F2/34 ,  C08F210/14 ,  C08F2500/08 ,  C08F2500/20 ,  C08F2500/11 ,  C08F2500/26

摘要： A process for the production of an ethylene alpha-olefin copolymer is disclosed, the process including polymerizing ethylene and at least one alpha-olefin by contacting the ethylene and the at least one alpha-olefin with a metallocene catalyst in at least one gas phase reactor at a reactor pressure of from 0.7 to 70 bar and a reactor temperature of from 20° C. to 150° C. to form an ethylene alpha-olefin copolymer. The resulting ethylene alpha-olefin copolymer may have a density D of 0.927 g/cc or less, a melt index (I2) of from 0.1 to 100 dg/min, a MWD of from 1.5 to 5.0. The resulting ethylene alpha-olefin copolymer may also have a peak melting temperature Tmax second melt satisfying the following relation: Tmax second melt>D*398−245.

摘要翻译： 公开了一种生产乙烯α-烯烃共聚物的方法，该方法包括通过在至少一个气相反应器中使乙烯和至少一种α-烯烃与茂金属催化剂接触来聚合乙烯和至少一种α-烯烃 反应器压力为0.7至70巴，反应器温度为20℃至150℃，形成乙烯α-烯烃共聚物。 得到的乙烯α-烯烃共聚物的密度D可以为0.927g / cc或更低，熔体指数（I 2/2）为0.1至100dg / min，MWD为1.5至5.0 。 所得到的乙烯α-烯烃共聚物也可以具有满足以下关系的峰值熔融温度T max max第二熔融物：T最大第二熔体 D * 398-245。

公开(公告)号：US08617116B2

公开(公告)日：2013-12-31

申请号：US12412464

申请日：2009-03-27

申请人： Christopher Davey

发明人： Christopher Davey

IPC分类号： A61M5/32

CPC分类号： A61M39/0247 ,  A61M39/0208 ,  A61M2039/0261 ,  A61M2039/0273 ,  A61M2039/0279 ,  A61M2039/0291

摘要： The present invention comprises an implantable subcutaneous port for anchoring a transcutaneous treatment component. The implantable subcutaneous port comprises a body portion and one or more frangible lines formed within the body portion. The body portion is adapted for receiving the transcutaneous treatment component beneath the point of entry into the physiology of a patient and routing the transcutaneous treatment component. The body portion is produced from a deformable material and has an area footprint and defines a support wall through which the transcutaneous treatment component enters the body portion. Fracturing the one or more frangible lines formed within the body portion enables removal of the body portion from the physiology of a patient through a transcutaneous opening defining an area of less than thirty percent of the area footprint of the body portion.

摘要翻译： 本发明包括用于锚定经皮处理组件的可植入皮下端口。 可植入的皮下端口包括主体部分和形成在主体部分内的一个或多个易碎线。 身体部分适于在进入患者生理学的点之下接收经皮治疗组件，并路由经皮治疗组件。 身体部分由可变形材料制成并且具有面积足迹并且限定了经皮处理组件通过该支撑壁进入身体部分。 在身体部分中形成的一个或多个易碎线的断裂能够通过限定小于身体部分的面积足迹的面积的面积的经皮开口从身体部分的生理学去除身体部分。

公开(公告)号：US20100249712A1

公开(公告)日：2010-09-30

申请号：US12412464

申请日：2009-03-27

申请人： Christopher Davey

发明人： Christopher Davey

IPC分类号： A61M5/162

CPC分类号： A61M39/0247 ,  A61M39/0208 ,  A61M2039/0261 ,  A61M2039/0273 ,  A61M2039/0279 ,  A61M2039/0291

摘要： The present invention comprises an implantable subcutaneous port for anchoring a transcutaneous treatment component. The implantable subcutaneous port comprises a body portion and one or more frangible lines formed within the body portion. The body portion is adapted for receiving the transcutaneous treatment component beneath the point of entry into the physiology of a patient and routing the transcutaneous treatment component. The body portion is produced from a deformable material and has an area footprint and defines a support wall through which the transcutaneous treatment component enters the body portion. Fracturing the one or more frangible lines formed within the body portion enables removal of the body portion from the physiology of a patient through a transcutaneous opening defining an area of less than thirty percent of the area footprint of the body portion.

摘要翻译： 本发明包括用于锚定经皮处理组件的可植入皮下端口。 可植入的皮下端口包括主体部分和形成在主体部分内的一个或多个易碎线。 身体部分适于在进入患者生理学的点之下接收经皮治疗组件，并路由经皮治疗组件。 身体部分由可变形材料制成并且具有面积足迹并且限定了经皮处理组件通过该支撑壁进入身体部分。 在身体部分中形成的一个或多个易碎线的断裂能够通过限定小于身体部分的面积足迹的面积的面积的经皮开口从身体部分的生理学去除身体部分。

公开(公告)号：US20100016835A1

公开(公告)日：2010-01-21

申请号：US12174582

申请日：2008-07-16

申请人： Christopher Davey

发明人： Christopher Davey

IPC分类号： A61M25/04

CPC分类号： A61M25/04

摘要： The present invention is a modular implantable medical device that is used deliver materials or energy into a patient's physiology, or from one region of a patient's physiology to another. The device includes a port element with a passageway therethrough for directing and anchoring a conduit element in a desired location. Both elements can be adjusted during placement to maximize the safety, comfort, and efficacy of use. In one embodiment, the port element is comprised of two components such that the passage way is formed after the components are assembled. This modularity enables a large diameter section of the conduit to be advanced past the port location, and the port to be assembled about a smaller proximal section of the conduit, thereby establishing full contact between the port and conduit elements to anchor the device in an optimal position.

摘要翻译： 本发明是一种模块化可植入医疗装置，其用于将材料或能量输送到患者的生理学中，或从患者的生理学的一个区域传递到另一个。 该装置包括具有穿过其中的通道的端口元件，用于将导管元件引导并锚定在所需位置。 两个元素可以在放置期间进行调整，以最大限度地提高使用的安全性，舒适性和有效性。 在一个实施例中，端口元件由两个部件组成，使得在组件组装之后形成通道。 该模块化使得管道的大直径部分能够超过端口位置，并且待组装的端口围绕导管的较小近端部分，从而在端口和导管元件之间建立完全接触，以将装置锚定在最佳状态 位置。

公开(公告)号：US20160213909A1

公开(公告)日：2016-07-28

申请号：US15088409

申请日：2016-04-01

申请人： Christopher Davey

发明人： Christopher Davey

IPC分类号： A61M39/02 ,  A61B17/50

CPC分类号： A61M39/0247 ,  A61B17/50 ,  A61M39/0208 ,  A61M2039/0223 ,  A61M2039/0232 ,  A61M2039/0261 ,  A61M2039/0273 ,  A61M2039/0279 ,  A61M2039/0291

摘要： The present invention comprises a deformable, implantable subcutaneous port for anchoring a transcutaneous treatment component. A port body portion having a normal area port footprint is adapted by means of a port orifice for receiving and anchoring the transcutaneous treatment component beneath the point of entry into the physiology of a patient and for routing the transcutaneous treatment component. The port body portion is produced from a deformable material and has structure and/or composition that provides deformability characteristics of the port such that collapsing, folding, stretching, elongating and/or twisting the port body portion into a modified port shape having a reduced-size port profile enables removal of the port body portion from the physiology of a patient through a relatively small transcutaneous opening.

摘要翻译： 本发明包括一种用于固定经皮处理组件的可变形植入式皮下端口。 具有正常区域端口覆盖区的端口主体部分通过端口孔口适配，用于接收并锚固经皮肤处理部件在进入患者生理学的位置之下并用于路由经皮治疗部件。 端口主体部分由可变形材料制成并且具有提供端口的可变形特性的结构和/或组合物，使得端口主体部分的折叠，折叠，拉伸，拉伸和/或扭曲成具有减小的端口形状的修改端口形状， 通过相对较小的经皮开口，能够将口部主体部分从患者的生理学中去除。

公开(公告)号：US09302088B2

公开(公告)日：2016-04-05

申请号：US14090246

申请日：2013-11-26

申请人： Christopher Davey

发明人： Christopher Davey

IPC分类号： A61M39/02

CPC分类号： A61M39/0247 ,  A61M39/0208 ,  A61M2039/0261 ,  A61M2039/0273 ,  A61M2039/0279 ,  A61M2039/0291

摘要： The present invention comprises an implantable subcutaneous port for anchoring a transcutaneous treatment component. The implantable subcutaneous port comprises a body portion and one or more frangible lines formed within the body portion. The body portion is adapted for receiving the transcutaneous treatment component beneath the point of entry into the physiology of a patient and routing the transcutaneous treatment component. The body portion is produced from a deformable material and has an area footprint and defines a support wall through which the transcutaneous treatment component enters the body portion. Fracturing the one or more frangible lines formed within the body portion enables removal of the body portion from the physiology of a patient through a transcutaneous opening defining an area of less than thirty percent of the area footprint of the body portion.

摘要翻译： 本发明包括用于锚定经皮处理组件的可植入皮下端口。 可植入的皮下端口包括主体部分和形成在主体部分内的一个或多个易碎线。 身体部分适于在进入患者生理学的点之下接收经皮治疗组件，并路由经皮治疗组件。 身体部分由可变形材料制成并且具有面积足迹并且限定了经皮处理组件通过该支撑壁进入身体部分。 在身体部分中形成的一个或多个易碎线的断裂能够通过限定小于身体部分的面积足迹的面积的面积的经皮开口从身体部分的生理学去除身体部分。

公开(公告)号：US08075531B2

公开(公告)日：2011-12-13

申请号：US12174582

申请日：2008-07-16

申请人： Christopher Davey

发明人： Christopher Davey

IPC分类号： A61M5/32 ,  A61M31/00 ,  A61M25/16

CPC分类号： A61M25/04

摘要： The present invention is a modular implantable medical device that is used deliver materials or energy into a patient's physiology, or from one region of a patient's physiology to another. The device includes a port element with a passageway therethrough for directing and anchoring a conduit element in a desired location. Both elements can be adjusted during placement to maximize the safety, comfort, and efficacy of use. In one embodiment, the port element is comprised of two components such that the passage way is formed after the components are assembled. This modularity enables a large diameter section of the conduit to be advanced past the port location, and the port to be assembled about a smaller proximal section of the conduit, thereby establishing full contact between the port and conduit elements to anchor the device in an optimal position.

摘要翻译： 本发明是一种模块化可植入医疗装置，其用于将材料或能量输送到患者的生理学中，或从患者的生理学的一个区域传递到另一个。 该装置包括具有穿过其中的通道的端口元件，用于将导管元件引导并锚定在所需位置。 两个元素可以在放置期间进行调整，以最大限度地提高使用的安全性，舒适性和有效性。 在一个实施例中，端口元件由两个部件组成，使得在组件组装之后形成通道。 该模块化使得管道的大直径部分能够超过端口位置，并且待组装的端口围绕导管的较小近端部分，从而在端口和导管元件之间建立完全接触，以将装置锚定在最佳状态 位置。

公开(公告)号：US07828078B2

公开(公告)日：2010-11-09

申请号：US11886372

申请日：2006-03-23

申请人： Wojciech Andrew Berger ,  Robert A. Spalletta ,  Jerry A. Carter ,  Richard M. Pell ,  Marian Mazurkiewicz ,  Christopher Davey

发明人： Wojciech Andrew Berger ,  Robert A. Spalletta ,  Jerry A. Carter ,  Richard M. Pell ,  Marian Mazurkiewicz ,  Christopher Davey

IPC分类号： E21B7/04

CPC分类号： E21B7/18

摘要： The present invention is a self-contained, high-energy liquid rock-boring system that will bore a small-diameter access hole [5] several hundred meters through hard granite and other obstacles within minutes of deployment. It employs a land unit [100] platform subsystem [1000] with an energetic fluid fuel reservoir [1300] and a boring subsystem [3000] having a plurality of pulsejets [3100]. Each pulsejet [3100] repeatedly ignites the energetic fluid [7] causing a plurality of rapidly-expanding gas bubbles [3250] which create and force a plurality liquid slugs [10] ahead of them rapidly out through a nozzle [3260] causing the slugs [10] to impact against materials ahead of the nozzles [3260], boring an access hole [5]. The system also employs an umbilical subsystem [2000] connecting the boring [3000] and the platform subsystems [1000]. The system can be used to rapidly bore an access hole [5] to provide air and resources to trapped miners. Alternatively, the system may also be used to bore an access hole [5] to underground threatening targets to neutralize them.

摘要翻译： 本发明是一种独立的高能液体钻孔系统，它将在几分钟内通过硬质花岗岩和其他障碍物钻出数百米的小直径通孔[5]。 它使用具有多个脉冲喷射器的高能流体燃料储存器[1300]和钻孔子系统[3000]的陆地单元[100]平台子系统[1000]。 每个脉冲喷枪[3100]反复点燃能量流体[7]，导致多个快速膨胀的气泡[3250]，其产生并迫使其上的多个液体块塞10迅速通过喷嘴[3260]流出，从而导致lug塞 [10]冲击喷嘴之前的材料[3260]，钻孔进入孔[5]。 该系统还采用连接镗孔[3000]和平台子系统[1000]的脐带子系统[2000]。 该系统可用于快速钻孔进入孔[5]，为被困的矿工提供空气和资源。 或者，该系统还可以用于向地下威胁目标钻一个进入孔[5]以中和它们。

公开(公告)号：US20070066966A1

公开(公告)日：2007-03-22

申请号：US11242101

申请日：2005-10-03

申请人： Christopher Davey

发明人： Christopher Davey

IPC分类号： A61K9/22

CPC分类号： A61M39/0247 ,  A61M2039/0261

摘要： The device of the present invention includes a modular, implantable catheterization port that is composed of a body portion, an interior port and an exterior port. The interior and exterior ports are selectively attachable to the body portion such that the device can be assembled by a clinician at the skin entry site without compromising the position of other portions of the device within and outside of the patient. The device further includes a first skirt and a second skirt that surround the exterior port at its junction with the body portion. Both skirts are designed to gradually affix themselves into the surrounding tissues of the patient's body during the initial phase of healing. The first skirt is composed of a bio-absorbable material such that in subsequent phases of healing its connection to the surrounding tissues diminishes, leaving the second skirt to maintain a mature, secure, and permanent connection to the tissues. The bio-absorbable material can be selected prior to assembly in order to ensure that the first skirt is fully absorbed at the conclusion of the procedure, thus permitting an easy and less-invasive removal of the device from the patient.

摘要翻译： 本发明的装置包括由主体部分，内部端口和外部端口组成的模块化的可植入导管插入口。 内部和外部端口可选择性地附接到主体部分，使得该装置可以由临床医生在皮肤进入部位组装，而不会影响患者内外的装置的其他部分的位置。 该装置还包括第一裙部和第二裙部，该裙部围绕外部端口在其与主体部分的连接处。 两个裙子都设计成在愈合的初始阶段逐渐将自己贴在患者身体的周围组织中。 第一个裙子由生物可吸收材料组成，使得在随后的愈合阶段，其与周围组织的连接减少，留下第二个裙部保持与组织的成熟，牢固和永久的连接。 生物吸收材料可以在组装之前进行选择，以便确保第一裙部在手术结束时被完全吸收，从而允许从患者容易且较少侵入性地移除该装置。

公开(公告)号：US09427554B2

公开(公告)日：2016-08-30

申请号：US13293820

申请日：2011-11-10

申请人： Christopher Davey

发明人： Christopher Davey

IPC分类号： A61M5/32 ,  A61M25/04

CPC分类号： A61M25/04

摘要： The present invention is an implantable medical device that is used deliver materials or energy into a patient's physiology, or from one region of a patient's physiology to another. The device includes a port element with a passageway therethrough for directing and anchoring a conduit element in a desired location. The implantable port stabilizes an elongated conduit within human physiology for long-term use, and includes a support passageway formed through the port and extending between an upper surface and a lower surface of the port, wherein the support passageway is sized and shaped for receiving the elongated conduit slideably inserted therethrough. The device includes a tissue ingrowth scaffold fixedly disposed on at least a portion of at least one surface of the implantable port for positioning in contact with adjacent tissue.

摘要翻译： 本发明是一种植入式医疗装置，其用于将材料或能量输送到患者的生理学中，或从患者的生理学的一个区域传递到另一个。 该装置包括具有穿过其中的通道的端口元件，用于将导管元件引导并锚定在所需位置。 可植入端口将人体生理学中的细长管道稳定长期使用，并且包括通过端口形成并在端口的上表面和下表面之间延伸的支撑通道，其中支撑通道的尺寸和形状用于接收 可滑动地插入其中的细长导管。 该装置包括固定地设置在可植入端口的至少一个表面的至少一部分上的组织向内生长支架，用于与相邻组织接触。