-
公开(公告)号：US20090130213A1
公开(公告)日：2009-05-21
申请号：US11979240
申请日：2007-10-31
申请人： Rajeev A. Jain , Stephen B. Ruddy , Kenneth lain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd
发明人： Rajeev A. Jain , Stephen B. Ruddy , Kenneth lain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd
IPC分类号： A61K9/10
CPC分类号： A61K9/5161 , A61K9/0056 , A61K9/145 , A61K9/146 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K9/2018 , A61K9/2054 , A61K9/2077 , A61K9/2081 , A61K9/5192
摘要： Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, or less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity.
摘要翻译： 公开了一种快速崩解的难溶性活性成分和至少一种药学上可接受的水溶性或水分散性赋形剂的固体口服剂型，其中所述难溶性活性成分颗粒在包含在剂型之前具有平均直径，或 小于约2000nm。 本发明的剂型具有将活性成分快速呈现和快速溶解在口腔中的优点。
-
公开(公告)号：US20080213371A1
公开(公告)日：2008-09-04
申请号：US12068706
申请日：2008-02-11
申请人： Rajeev A. Jain , Stephen B. Ruddy , Kenneth lain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd
发明人： Rajeev A. Jain , Stephen B. Ruddy , Kenneth lain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd
IPC分类号： A61K9/00 , A61K31/192
CPC分类号： A61K9/5161 , A61K9/0056 , A61K9/145 , A61K9/146 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K9/2018 , A61K9/2054 , A61K9/2077 , A61K9/2081 , A61K9/5192
摘要： Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, of less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity.
摘要翻译： 公开了一种快速崩解的难溶性活性成分和至少一种药学上可接受的水溶性或水分散性赋形剂的固体口服剂型，其中所述难溶性活性成分颗粒在包含在剂型中之前具有平均直径 小于约2000nm。 本发明的剂型具有将活性成分快速呈现和快速溶解在口腔中的优点。
-
公开(公告)号：US20120114754A1
公开(公告)日：2012-05-10
申请号：US13291873
申请日：2011-11-08
申请人： Rajeev A. Jain , Stephen B. RUDDY , Kenneth Iain CUMMING , Maurice Joseph Anthony CLANCY , Janet Elizabeth CODD
发明人： Rajeev A. Jain , Stephen B. RUDDY , Kenneth Iain CUMMING , Maurice Joseph Anthony CLANCY , Janet Elizabeth CODD
IPC分类号： A61K9/14 , A61K31/4422 , A61P29/00 , A61K31/192 , A61K31/4965 , B82Y40/00 , B82Y5/00
CPC分类号： A61K9/5161 , A61K9/0056 , A61K9/145 , A61K9/146 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K9/2018 , A61K9/2054 , A61K9/2077 , A61K9/2081 , A61K9/5192
摘要： Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water-dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, of less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity.
摘要翻译： 公开了一种快速崩解的难溶性活性成分和至少一种药学上可接受的水溶性或水分散性赋形剂的固体口服剂型，其中所述难溶性活性成分颗粒在包含在剂型之前具有平均直径， 小于约2000nm。 本发明的剂型具有将活性成分快速呈现和快速溶解在口腔中的优点。
-
公开(公告)号：US06316029B1
公开(公告)日：2001-11-13
申请号：US09572961
申请日：2000-05-18
申请人： Rajeev A. Jain , Stephen B. Ruddy , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd
发明人： Rajeev A. Jain , Stephen B. Ruddy , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd
IPC分类号： A61K914
CPC分类号： A61K9/0056 , A61K9/145 , A61K9/146 , A61K9/1617 , A61K9/1623 , A61K9/1652 , A61K9/2018 , A61K9/2054 , A61K9/2077 , A61K9/2081 , A61K9/5161 , A61K9/5192 , Y10S977/906
摘要： Disclosed is a rapidly disintegrating solid oral dosage form of a poorly soluble active ingredient and at least one pharmaceutically acceptable water-soluble or water-dispersible excipient, wherein the poorly soluble active ingredient particles have an average diameter, prior to inclusion in the dosage form, of less than about 2000 nm. The dosage form of the invention has the advantage of combining rapid presentation and rapid dissolution of the active ingredient in the oral cavity.
摘要翻译： 公开了一种快速崩解的难溶性活性成分和至少一种药学上可接受的水溶性或水分散性赋形剂的固体口服剂型，其中所述难溶性活性成分颗粒在包含在剂型之前具有平均直径， 小于约2000nm。 本发明的剂型具有将活性成分快速呈现和快速溶解在口腔中的优点。
-
公开(公告)号：US20130011447A1
公开(公告)日：2013-01-10
申请号：US13620570
申请日：2012-09-14
申请人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary G. Liversidge
发明人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary G. Liversidge
CPC分类号： A61K9/146 , A61K9/2054 , A61K9/2077
摘要： Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer.
摘要翻译： 描述了包含要施用的纳米颗粒剂的控释纳米颗粒制剂和用于在施用后延长试剂释放的速率控制聚合物。 该新型组合物在施用后释放约2至约24小时或更长时间的时间。
-
公开(公告)号：US20080248123A1
公开(公告)日：2008-10-09
申请号：US12078027
申请日：2008-03-26
申请人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary Liversidge
发明人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary Liversidge
IPC分类号： A61K9/14 , A61K31/551 , A61K31/5513 , A61K31/53 , A61K31/519 , A61K31/135 , A61K31/44 , A61K31/415 , A61K38/13 , A61K31/56 , A61K31/52 , A61P25/08 , A61P37/06
CPC分类号： A61K9/2077 , A61K9/146 , A61K9/2054
摘要： Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer.
摘要翻译： 描述了包含要施用的纳米颗粒剂的控释纳米颗粒制剂和用于在施用后延长试剂释放的速率控制聚合物。 该新型组合物在施用后释放约2至约24小时或更长时间的时间。
-
公开(公告)号：US20090297619A1
公开(公告)日：2009-12-03
申请号：US12483188
申请日：2009-06-11
申请人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary G. Liversidge
发明人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary G. Liversidge
IPC分类号： A61K9/14 , A61P37/02 , A61K31/55 , A61K31/5513 , A61K31/5517 , A61K31/53 , A61K31/519 , A61K31/135 , A61K31/437 , A61K31/4164 , A61K38/13 , A61K31/52 , A61K31/573
CPC分类号： A61K9/2077 , A61K9/146 , A61K9/2054
摘要： Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer.
摘要翻译： 描述了包含要施用的纳米颗粒剂的控释纳米颗粒制剂和用于在施用后延长试剂释放的速率控制聚合物。 该新型组合物在施用后释放约2至约24小时或更长时间的时间。
-
公开(公告)号：US08293277B2
公开(公告)日：2012-10-23
申请号：US09337675
申请日：1999-06-22
申请人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary Liversidge
发明人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary Liversidge
CPC分类号： A61K9/146 , A61K9/2054 , A61K9/2077
摘要： Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer.
摘要翻译： 描述了包含要施用的纳米颗粒剂的控释纳米颗粒制剂和用于在施用后延长试剂释放的速率控制聚合物。 该新型组合物在施用后释放约2至约24小时或更长时间的时间。
-
公开(公告)号：US08236352B2
公开(公告)日：2012-08-07
申请号：US10701064
申请日：2003-11-05
申请人： H. William Bosch , Niels P. Ryde , Rajeev A. Jain , Jon Swanson , Robert Hontz , John G. Devane , Kenneth Ian Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary G. Liversidge
发明人： H. William Bosch , Niels P. Ryde , Rajeev A. Jain , Jon Swanson , Robert Hontz , John G. Devane , Kenneth Ian Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary G. Liversidge
CPC分类号： A61K9/1623 , A61K9/0056 , A61K9/146 , A61K9/1617 , A61K9/1652 , A61K9/2018 , A61K9/2054 , A61K9/2077 , A61K9/2081
摘要： The present invention is directed to nanoparticulate compositions comprising glipizide. The glipizide particles of the composition preferably have an effective average particle size of less than about 2 microns.
摘要翻译： 本发明涉及包含格列吡嗪的纳米颗粒组合物。 组合物的格列吡嗪颗粒优选具有小于约2微米的有效平均粒度。
-
公开(公告)号：US20110300210A1
公开(公告)日：2011-12-08
申请号：US13102795
申请日：2011-05-06
申请人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary Liversidge
发明人： Jon Swanson , Rajeev A. Jain , Robert Hontz , John G. Devane , Kenneth Iain Cumming , Maurice Joseph Anthony Clancy , Janet Elizabeth Codd , Gary Liversidge
IPC分类号： A61K9/14 , A61K9/48 , A61K9/28 , A61K9/20 , A61K31/551
CPC分类号： A61K9/2077 , A61K9/146 , A61K9/2054
摘要： Described are controlled release nanoparticulate formulations comprising a nanoparticulate agent to be administered and a rate-controlling polymer which functions to prolong the release of the agent following administration. The novel compositions release the agent following administration for a time period ranging from about 2 to about 24 hours or longer.
摘要翻译： 描述了包含要施用的纳米颗粒剂的控释纳米颗粒制剂和用于在施用后延长试剂释放的速率控制聚合物。 该新型组合物在施用后释放约2至约24小时或更长时间的时间。
-
-
-
-
-
-
-
-
-
搜索结果
14 条记录 (耗时 0.032 秒)
