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公开(公告)号：US20100255095A1
公开(公告)日：2010-10-07
申请号：US12528628
申请日：2008-02-23
IPC分类号： A61K9/24 , A61K31/216 , A61P3/06
CPC分类号： A61K9/2031 , A61K9/1641 , A61K9/2077 , A61K31/216
摘要： The invention relates to pharmaceutical compositions comprising unmicronized fenofibrate in admixture with a wetting agent and one or more pharmaceutically acceptable excipients, wherein the admixture is not comicronized before processing. The invention also relates to processes for the preparation of such compositions.
摘要翻译： 本发明涉及包含非微量非诺贝特与润湿剂和一种或多种药学上可接受的赋形剂混合的药物组合物，其中所述混合物在加工之前不被光晕化。 本发明还涉及制备这种组合物的方法。
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公开(公告)号：US08852635B2
公开(公告)日：2014-10-07
申请号：US12528628
申请日：2008-02-23
IPC分类号： A61K9/24 , A61K9/16 , A61K9/20 , A61K31/216
CPC分类号： A61K9/2031 , A61K9/1641 , A61K9/2077 , A61K31/216
摘要： The invention relates to pharmaceutical compositions comprising unmicronized fenofibrate in admixture with a wetting agent and one or more pharmaceutically acceptable excipients, wherein the admixture is not comicronized before processing. The invention also relates to processes for the preparation of such compositions.
摘要翻译： 本发明涉及包含非微量非诺贝特与润湿剂和一种或多种药学上可接受的赋形剂混合的药物组合物，其中所述混合物在加工之前不被光晕化。 本发明还涉及制备这种组合物的方法。
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公开(公告)号：US20110097414A1
公开(公告)日：2011-04-28
申请号：US12528627
申请日：2008-02-26
申请人： Roshan lal Sandal , Vikrant Thakkar , Ramakant Kashinath Gundu , Rahul Sudhakar Dabre , Narayanan Murali , Girish Kumar Jain
发明人： Roshan lal Sandal , Vikrant Thakkar , Ramakant Kashinath Gundu , Rahul Sudhakar Dabre , Narayanan Murali , Girish Kumar Jain
IPC分类号： A61K9/14 , A61K31/235
CPC分类号： A61K9/143 , A61K9/1635 , A61K9/1652 , A61K31/216
摘要： The present invention provides a pharmaceutical composition comprising adsorbate of fenofibrate or salt thereof or fenofibrate adsorbed on a pharmaceutically acceptable adsorbent and optionally one or more pharmaceutically acceptable excipients. The invention also relates to processes for the preparation of such compositions.
摘要翻译： 本发明提供药物组合物，其包含非诺贝特或其盐的吸附物或吸附在药学上可接受的吸附剂上的非诺贝特和任选的一种或多种药学上可接受的赋形剂。 本发明还涉及制备这种组合物的方法。
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4.发明申请Device For The Manufacture Of A Dosage Form With A Hole And Method Of Manufacture 审中-公开用于制造具有孔的剂型的装置和制造方法公开(公告)号：US20130059062A1
公开(公告)日：2013-03-07
申请号：US13582452
申请日：2011-03-07
CPC分类号： B30B15/065 , A61K9/2072
摘要： This invention is related to a device for the manufacture of a dosage form with a hole and method of manufacture. The dosage form may be a modified release dosage form comprising a core coated with a polymeric coat comprising one or more rate controlling polymers, said dosage form having a hole extending through the dosage form resulting in an inner radial surface and an outer radial surface, said core comprising at least one therapeutically active ingredient, characterized in that the inner radial surface is partially coated with said polymeric coat.
摘要翻译： 本发明涉及一种用于制造具有孔的剂型和制造方法的装置。 剂型可以是包含涂覆有包含一种或多种速率控制聚合物的聚合物涂层的芯的调释剂型，所述剂型具有延伸穿过剂型的孔，产生内径向表面和外径向表面，所述孔 芯包含至少一种治疗活性成分，其特征在于，所述内部径向表面部分地涂覆有所述聚合物涂层。
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