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公开(公告)号:US06420473B1
公开(公告)日:2002-07-16
申请号:US09501866
申请日:2000-02-10
申请人: Ramireddy Chittamuru , George Reyes , Thomas P. Farrell , Charles F. Vesey , Dev K. Mehra , Hans-Ulrich Petereit , Klaus Lehmann
发明人: Ramireddy Chittamuru , George Reyes , Thomas P. Farrell , Charles F. Vesey , Dev K. Mehra , Hans-Ulrich Petereit , Klaus Lehmann
IPC分类号: C08J312
CPC分类号: A61K9/2893 , A61K9/2813 , A61K9/2846 , A61K47/02
摘要: A non-toxic, edible, enteric film coating, dry powder composition for use in making an aqueous enteric suspension which may be used in coating pharmaceutical tablets comprises a) an acrylic resin, said resin comprising i) from 20 to 85 percent by weight of at least one alkyl acrylate or alkyl methacrylate moiety, ii) from 80 to 15 percent by weight of at least one vinyl or vinylidene moiety having a carboxylic acid group capable of salt formation, and iii) from 0 to 30 percent by weight of at least one other vinyl or vinylidene moiety copolymerizable with i) and ii), b) an alkalizing agent capable of reacting with the acrylic resin such that, after reaction, 0.1 to 10 mole percent of the acidic groups in 1a-ii) are present in the salt form, and c) a detackifier.
摘要翻译: 可用于制备可用于包衣药物片剂的水性肠溶悬浮液的无毒,可食用的肠溶薄膜包衣干粉组合物包括a)丙烯酸树脂,所述树脂包含i)20至85重量% 至少一种丙烯酸烷基酯或甲基丙烯酸烷基酯部分,ii)80至15重量%的至少一个具有能够形成盐的羧酸基团的乙烯基或亚乙烯基部分,和iii)至少0至30重量% 可与i)和ii)共聚的另一个乙烯基或亚乙烯基部分,b)能够与丙烯酸类树脂反应的碱化剂,使得反应后,1a-ii)中的0.1〜10摩尔%的酸性基团存在于 盐形式,和c)防粘剂。
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公开(公告)号:US06274162B1
公开(公告)日:2001-08-14
申请号:US09480969
申请日:2000-01-14
IPC分类号: A61K4700
CPC分类号: A61K9/2873 , A01C1/06 , A23B9/14 , A23G3/343 , A23G2200/00 , A23P20/10 , A23P20/105 , A61K9/282 , A61K9/284 , A61K9/2853 , A61K9/286 , A61K9/2866
摘要: A dry film coating composition for forming a coating suspension for film coating pharmaceuticals, food, confectionery forms, agricultural seeds, and the like, comprises (1) a primary film former, the primary film former comprising low bloom strength gelatin, or hydroxyethyl cellulose, or a combination thereof, and (2) a secondary film former, or a plasticizer, or a surfactant, or a glidant, or a suspension aid, or a colorant, or a flavorant, or a combination thereof.
摘要翻译: 用于形成用于薄膜包衣的药物,食品,糖果形式,农业种子等的涂覆悬浮液的干膜涂料组合物包括(1)初始成膜剂,包含低绽放强度明胶或羟乙基纤维素的初级成膜剂, 或其组合,和(2)二次成膜剂,增塑剂或表面活性剂,助流剂,悬浮助剂或着色剂,香料或其组合。
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